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D.J. Reed CB | DET
Lions' D.J. Reed: Working through rib injury
Reed (ribs) was a limited participant in Wednesday's practice.
Reed presumably picked up the injury during the Lions' 31-24 win over the Jets in Week 3, when he played 62 of 66 defensive snaps (93.9 percent) and finished with eight tackles (five solo) and one pass defense. He'll have two more chances to increase his practice participation to full and avoid an injury designation for Sunday's road game against the Panthers.
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Frankie Luvu LB | WAS
Commanders' Frankie Luvu: Estimated as limited participant Wednesday
Luvu (groin) was estimated as a limited participant on the Commanders' official injury report Wednesday.
Luvu has not been able to practice at all since straining his groin back in Week 1 at Philadelphia, but it looks like he may now be trending in the right direction. If he can actually practice Thursday or Friday, he'll at least have a chance to return to game action Sunday versus the Colts.
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Tylan Wallace WR | CLE
Browns' Tylan Wallace: Won't play against Pittsburgh
Wallace (knee) has been ruled out for Thursday's game against the Steelers.
A knee injury prevented Wallace from practicing all week, so the sixth-year pro will observe Thursday's game from the sidelines, which means Isaiah Bond and Malachi Corley are both in line to see a slight uptick in offensive snaps. Wallace's next opportunity to play is Week 5 against the Jets on Sunday, Oct. 11.
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Mykel Williams DE | SF
49ers' Mykel Williams: Opens practice window
The 49ers opened Williams' (knee) 21-day practice window Wednesday to return from the reserve/PUP list, Matt Maiocco of NBC Sports Bay Area reports.
Williams spent his first practice back with the 49ers as a limited participant. The team has until Oct. 21. to add the linebacker to the 53-man roster, or he will remain on the reserve/PUP list for the remainder of the 2026 season. Williams is still recovering from a torn ACL he suffered in November 2025 but could suit up for game day as soon as Week 5.
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Grant Delpit SAF | CLE
Browns' Grant Delpit: Logs full practice Wednesday
Delpit (shoulder) was a full participant in Wednesday's practice session.
Delpit was able to play through a shoulder issue during the Browns' 21-18 win over the Panthers on Sunday, and the seventh-year pro will do the same for Thursday's AFC North clash. He's played every single defensive snap through three regular-season games, accumulating 12 tackles (eight solo), including 1.0 sacks and one pass defense in that span.
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Mo Alie-Cox TE | IND
Colts' Mo Alie-Cox: Misses practice with illness
Alie-Cox (illness) did not participate at practice Wednesday.
The nature of Alie-Cox's ailment is unknown, so it's not clear whether his availability for Week 4 is in any jeopardy. If he can return to practice Thursday or Friday, he'll put himself in a good position to suit up Sunday at Washington.
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DeVonta Smith WR | PHI
Eagles' DeVonta Smith: Listed as DNP on Wednesday
Smith missed Wednesday's walkthrough due to a hamstring injury.
Smith also kicked off last week with a DNP on the Eagles' first practice report due to a hamstring issue, only to progress to full and no designation ahead of Monday's road matchup with the Bears. In the end, though, his status bears watching in the coming days to ensure he's also good to go for Sunday's contest against the Rams.
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Azeez Al-Shaair LB | HOU
Texans' Azeez Al-Shaair: Considered week-to-week
Coach DeMeco Ryans said Wednesday that Al-Shaair is "week-to-week" with the groin injury he suffered during Sunday's game at Indianapolis, Jonathan M. Alexander of the Houston Chronicle reports.
Al-Shaair was able to return to action in Week 3 after checking out of the game with the groin injury, but his outlook for Week 4 is now up in the air. He'll probably have to practice in full Thursday or Friday to avoid carrying an injury designation into the weekend.
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Tyson Campbell CB | CLE
Browns' Tyson Campbell: Good to go for TNF
Campbell (knee) was a full participant in Wednesday's practice.
Campbell opened the week with back-to-back DNPs before fully practicing Wednesday, putting him on track to play in Thursday's AFC North showdown against the Steelers. With Campbell back in the fold, Mekhi Blackmon will revert to a depth role in the secondary for Week 4. Campbell has 12 tackles (seven solo) through two regular-season games.
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Marvin Mims WR | DEN
Broncos' Marvin Mims: Practices fully Wednesday
Mims (foot) was a full participant in Wednesday's practice.
Mims has missed the last two games with a foot injury, but his full practice Wednesday puts him track to play Sunday against the 49ers. Mims ran just nine routes in Week 1 against the Chiefs and is likely to remain in a bit role behind Jaylen Waddle, Courtland Sutton and Pat Bryant at wide receiver.