Kirilloff (shoulder) says he's back to full baseball activities, but the Twins will wait several more days to see if he's healthy enough to send him on a rehab assignment, Dan Hayes of The Athletic reports.

Kirilloff received a cortisone injection for his strained right shoulder in early August, and he's been able to ramp up his baseball work over the past couple weeks. It sounds like he could return in early September if he begins a rehab assignment by early next week.

Isaac, who was promoted to High-A Bowling Green on Tuesday, hit his first home run at that level Thursday against Winston-Salem.

Arguably the best first base prospect in the minors, Isaac has yet to face much resistance in pro ball, save for the fact he has a .672 OPS in 91 plate appearances against same-handed pitchers compared to a .907 OPS in 295 plate appearances against righties. The 6-foot-3, 240-pound 19-year-old will need to keep mashing at each level of the minors, given his lack of defensive versatility, but he has at least 70-grade raw power and has a 20.7 percent strikeout rate while being young for Single-A and High-A.

Casas is not in the lineup for Thursday's tilt in Houston, Christopher Smith of The Springfield Republican reports.

Casas is not dealing with any known injury, but it's odd to see him not starting versus a right-hander, especially after he just missed two games over the weekend with a tooth infection. Justin Turner is at first base Thursday, with Masataka Yoshida in the designated hitter spot.

Abreu is not in the lineup for Thursday's game versus the Red Sox, Matt Kawahara of the Houston Chronicle reports.

Abreu started Wednesday in his first game back off the injured list, but he'll yield to Jon Singleton on Thursday. The veteran first baseman had missed a couple weeks of action with a nagging back issue.

Raley is out of the lineup for Wednesday's game against the Rockies, Marc Topkin of the Tampa Bay Times reports.

The lefty-hitting Raley will retreat to the bench while the Rockies bring southpaw Austin Gomber to the hill Wednesday. The Rays will roll out a starting outfield of Randy Arozarena, Jose Siri and Josh Lowe from left to right while Harold Ramirez serves as the team's designated hitter.

Schanuel is out of the lineup for the first game of Wednesday's doubleheader with the Reds.

Schanuel will take a seat for the first time since his promotion from Double-A Rocket City on Friday. He started at first base and served as the Angels' leadoff man in each of the past four games, going 4-for-15 with four base hits, two walks and four runs. The lefty-hitting Schanuel's absence from the lineup for the first game of the day comes with southpaw Andrew Abbott on the hill for Cincinnati, but so long as he can retain a regular spot atop the order versus righties, the 21-year-old rookie could be an excellent source of runs while batting in front of Shohei Ohtani and Mike Trout.

Houston activated Abreu (back) from the 10-day injured list Wednesday. He'll start at first base and bat sixth in the Astros' game against the Red Sox.

Abreu will return to action after missing about two weeks due to lower-back inflammation. He was in a 3-for-35 rut at the dish prior to the IL stint and has struggled to a .234/.291/.343 batting line in 464 total plate appearances overall this season.

Calhoun is out of the lineup for Wednesday's game against the Dodgers, Joe Noga of The Cleveland Plain Dealer reports.

Calhoun will hit the bench Wednesday while Guardians manager Terry Francona stocks up on right-handed bats to counter Dodgers southpaw Clayton Kershaw. Gabriel Arias will step in at first base in place of Calhoun, who has slugged home runs in both of his last two starts.

Diaz went 3-for-5 with a double, two RBI and two runs scored in Tuesday's 12-4 victory over the Rockies.

Diaz now has multiple hits in five consecutive contests, going 11-for-25 during that stretch. While the first baseman hasn't homered since Aug. 6, it's hard to complain about his .407 batting average in the 13 games since then.

Manzardo (shoulder) was activated from Triple-A Columbus' 7-day injured list Wednesday.

Manzardo went 0-for-8 with a walk, one RBI and a run scored over three games while rehabbing with the Guardians' Arizona Complex League affiliate. He's now clear to make his Columbus debut following a trade that sent him from the Rays organization. A strong showing with the Clippers could make him an option for a late-season call-up to Cleveland.