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Andrew Kittredge RP | BAL
Orioles' Andrew Kittredge: Returns from 15-day IL
The Orioles activated Kittredge (knee) from the 15-day injured list Wednesday.
Kittredge is ready to make his season and Orioles debuts after recovering from arthroscopic knee surgery in early March. The veteran reliever is lined up to serve in a setup role, although he could be eased into high-leverage situations.
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Forrest Whitley RP | TB
Astros' Forrest Whitley: Activated from injured list
The Astros activated Whitley (knee) from the 15-day injured list Wednesday, Matt Kawahara of the Houston Chronicle reports.
Whitley has dealt with two separate knee injuries this season that have limited him to only one appearance with the Astros. He tossed two perfect innings with four strikeouts during his most recent rehab assignment and is ready to rejoin the Houston bullpen.
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Daniel Lynch IV RP | KC
Royals' Daniel Lynch: Getting first start of season
Lynch is slated to start Wednesday's game against the Giants in San Francisco, Jaylon T. Thompson of The Kansas City Star reports.
Lynch has 54 career MLB starts on his ledger, but he's made all but three of his 36 appearances out of the bullpen since the 2024 season and has pitched exclusively in relief so far in 2025. The recent moves of Cole Ragans (groin) and Seth Lugo (finger) to the injured list will temporarily create an opening in the rotation, and Lynch could serve as the Royals' No. 5 starter until one of two injured hurlers is activated. Lynch has maxed out at two innings out of the bullpen this season and hasn't recorded more than four outs in an appearance since May 3, so the Royals could look to cap him at around 40-to-50 pitches Wednesday and treat the game as more of a bullpen day. Taylor Clarke and Angel Zerpa should be relatively fresh out of the bullpen and would likely be capable of giving the Royals multiple innings, if needed.
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Casey Lawrence RP | SEA
Mariners' Casey Lawrence: Excels in bulk relief
Lawrence (1-2) took the loss Tuesday against the White Sox after allowing one run on six hits and no walks while striking out two in five innings.
Lawrence made his season debut with the Mariners after inking a minor-league contract with the club earlier this month, and he gave them five strong innings as a bulk reliever. The White Sox scratched a run across in the third inning and that proved to be the difference after the Mariners were shut out by Adrian Houser and the bullpen. Five innings tied for Lawrence's longest outing this season and he now has a 4.08 ERA, 1.53 WHIP and 7:1 K:BB in 17.2 innings this season.
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Jordan Leasure RP | CHW
White Sox's Jordan Leasure: Earns first save of 2025
Leasure earned his first save of the season in Tuesday's win over the Mariners after tossing a scoreless ninth inning. He allowed one hit and no walks while striking out two.
Leasure worked around a two-out double from Donovan Solano to close out the game for his first save this season and third save of his career. He's now punched out eight batters in his last four innings and has compiled five holds and a save in May. For the season, Leasure owns a 3.86 ERA, 1.47 WHIP and 24:8 K:BB in 16.1 innings.
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Brennan Bernardino RP | COL
Red Sox's Brennan Bernardino: Thrives in tough spot
Bernardino allowed one hit over 1.2 scoreless innings in Tuesday's 2-0 win over the Mets. He did not record a walk or a strikeout.
Bernardino was needed unexpectedly after starter Walker Buehler was tossed for arguing balls and strikes in the middle of an at-bat against Juan Soto in the third inning. Bernardino threw a couple pitches that were not close for a walk that was charged to Buehler. The lefty then got the next two hitters before pitching around a leadoff double in the fourth to extend a scoreless run to nine innings dating back to April 29.
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Justin Slaten RP | BOS
Red Sox's Justin Slaten: Extends scoreless stretch
Slaten retired all five batters faced to earn a hold in Tuesday's 2-0 win over the Mets.
Slaten entered the middle of the seventh inning with a runner at first base and induced a double-play grounder to squelch the threat. He then got three harmless groundouts in the eighth. Slaten endured a three-game hiccup at the end of April/beginning of May (six runs, 2.1 innings), but the right-hander has been on point since. Tuesday's work extended a scoreless streak to 7.2 innings, during which he hasn't allowed a hit or a walk.
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Tommy Kahnle RP | BOS
Tigers' Tommy Kahnle: Secures sixth save
Kahnle earned the save in Tuesday's win over the Cardinals, tossing a perfect ninth inning while picking up a strikeout.
Kahnle was called upon for the save after Will Vest pitched the eighth inning against the heart of the Cards' order. Kahnle retired the side on 12 pitches for his first save since April 30. Kahnle leads the team with six saves this season, but Vest leads the team in May with two saves. They both have been effective in the role, as the Tigers continue to roll with a committee. Kahnle has had an excellent season, posting a 1.37 ERA, 0.81 WHIP and 20:6 K:BB in 19.2 innings.
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Kenley Jansen RP | DET
Angels' Kenley Jansen: Earns 10th save
Jansen allowed a run on two hits and struck out two over one inning to earn the save in Tuesday's 7-5 win over the Athletics.
Jansen gave up a run in a save situation for the first time this season, but he had a three-run cushion to work with. He's had a heavy workload of late, pitching four of the last five days, which may explain his struggles Tuesday. The 37-year-old is up to 10 saves while adding a 5.28 ERA, 1.37 WHIP and 15:3 K:BB across 15.1 innings. Should a save situation arise Wednesday, Ryan Zeferjahn, Brock Burke or Hector Neris could be options to step in, as it's unlikely Jansen will be asked to pitch three days in a row.
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Brant Hurter RP | DET
Tigers' Brant Hurter: Getting start in bullpen game
Hurter will start Wednesday against the Cardinals in what's expected to be a bullpen game for the Tigers, Chris McCosky of The Detroit News reports.
Hurter frequently served as a bulk reliever for the Tigers in the second half of 2024, but he's occupied a more traditional relief role through the first two months of this season after missing out on a spot in the Opening Day rotation. The 26-year-old southpaw has pitched well over his 13 appearances, compiling a 2.35 ERA and 0.96 WHIP across 23 frames. He hasn't tossed more than 30 pitches in an appearance since April 26, so Hurter may not be asked to work deep enough into Wednesday's start to qualify for a win.