Ewers (coach's decision) is inactive for Sunday's game against the Chargers but will serve as the emergency third QB.

It's a role that the Texas product has been playing all season behind Tua Tagovailoa and Zach Wilson. Ewers would need those two to get sick, injured or ejected to have a chance to play.

Milroe (coach's decision) is inactive for Sunday's matchup with the Jaguars but will serve as the emergency third quarterback.

Milroe would need starter Sam Darnold and backup Drew Lock to get injured, sick or ejected to have a chance to play. The Alabama product and 2025 third-round pick has yet to attempt a pass in his pro career.

Richardson is inactive for Sunday's game against the Cardinals after sustaining an eye injury while doing pregame work with resistance bands, Joel A. Erickson of The Indianapolis Star reports.

The Colts haven't provided word on the severity of the injury, but Richardson was apparently in enough discomfort that the team elected to make him inactive for the first time this season. Richardson had suited up as starting quarterback Daniel Jones' top backup for each of the first five games and saw action late in blowout wins in Weeks 3 and 5, but rookie Riley Leonard is now slated to handle the No. 2 role Sunday.

Richardson is inactive for Sunday's game against the Cardinals, Amanda Foster of the Colts' official site reports.

Per Ian Rapoport of NFL Network, Richardson sustained an unspecified injury during warmups, so the quarterback isn't a healthy inactive for the contest. Riley Leonard is thus slated to serve as Daniel Jones' top backup Sunday.

DeVito (coach's decision) is inactive for Sunday's game against the Saints but will serve as the emergency third quarterback.

DeVito will remain as the Patriots' emergency third quarterback, meaning he will only see the field in New Orleans if Drake Maye and Joshua Dobbs were to depart due to injury, illness or ejection.

Brissett is starting Sunday's game at Indianapolis with Kyler Murray (foot) inactive, Darren Urban of the Cardinals' official site reports.

Brissett has been preparing to lead the Cardinals offense Week 6 due to Murray's foot injury, which was described as a mid-foot sprain by Ian Rapoport of NFL Network on Saturday evening that may require more than one week on the sideline. With Murray confirmed to be out this Sunday, Brissett will earn a start for the fifth different team in his 10-year career. He went 1-4 last season as a member of the Patriots, when he completed 79 of 135 passes (58.5 percent) for 696 yards, two touchdowns and one interception, had 12 carries for 51 yards and no TDs and fumbled three times (one lost) in those nods.

Murray (foot) is listed as inactive Sunday at Indianapolis.

Murray made a brief exit due to a foot injury Week 5 against the Titans and then didn't practice Wednesday or Thursday before returning in a limited capacity Friday and earning a questionable designation for Week 6. Both Adam Schefter of ESPN and Ian Rapoport of NFL Network reported Saturday evening that Murray wasn't expected to play Sunday, and Rapoport even noted the quarterback is dealing with a mid-foot sprain that may require more than one week on the sideline. For as long as Murray is unavailable, Jacoby Brissett will direct the Cardinals offense.

McCarthy (ankle) was able to get in some "good work" on the field during the Vikings' Week 6 bye, but he's still not considered 100 percent healthy and is uncertain to be available for the team's Week 7 game against the Eagles, Tom Pelissero of NFL Network reports.

Peliserro notes that McCarthy will reclaim starting quarterback duties for the Vikings once he's considered ready for game action, but the second-year signal-caller still has a few hurdles to clear before stepping back in under center for Minnesota. McCarthy is expected to be ready to practice in some fashion during the upcoming week for the first time since suffering a right high-ankle sprain in a Sept. 14 loss to Atlanta, but he'll need to prove that his mobility isn't affected by the injury and that he's "comfortable from an operational perspective" in order to gain clearance to play, according to Pelissero. Meanwhile, Carson Wentz -- who started each of the past three games -- could be limited in practice this week while he tends to an injury to his non-throwing shoulder, leaving the Vikings' quarterback situation unsettled coming out of the bye.

Smith will remain the Raiders' starting quarterback for Sunday's game against the Titans after Las Vegas had "no serious discussion" about benching the signal-caller following the team's four-game losing streak, Tom Pelissero of NFL Network reports.

Much of the team's struggles over the past four games have fallen on Smith's shoulders, as the veteran quarterback has thrown eight interceptions and has taken 12 sacks over that stretch. Poor offensive line play hasn't helped Smith, and he'll be further handicapped Sunday by the continued absence of star tight end Brock Bowers (knee), who is set to miss a second straight game. Though the Raiders aren't yet prepared to turn the offense over to backup Kenny Pickett, the idea of a change under center could gain some momentum if Smith is unable to deliver a clean outing against the Titans, who rank in the bottom 10 of the league in both yards and points allowed per game.

Purdy (toe), who has been ruled out ahead of Sunday's game at Tampa Bay, has "a chance" to play Week 7 against the Falcons, Adam Schefter of ESPN reports.

Purdy will miss his second straight game -- and fourth so far this season -- this Sunday due to a lingering toe injury. The quarterback didn't practice at all this week, but he did do some work off to the side, so he appears to at least be making some progress toward a return. Nonetheless, Purdy's status remains up in the air for next week, though Schefter's report does provide some optimism about Purdy's ability to get back on the field. For as long as Purdy remains out, Mac Jones -- who is dealing with knee and oblique injuries but is expected to play this Sunday -- will likely remain San Francisco's starter behind center.