Mayfield completed 29 of 33 pass attempts for 379 yards and two touchdowns while rushing five times for 15 yards in Sunday's 38-35 win over the Seahawks.

Mayfield flirted with perfection in a masterful performance that saw him miss just four pass attempts while committing zero turnovers. The 30-year-old was especially sharp in the clutch when he led a pair of five-play drives that took up a little over one minute of game clock to give Tampa Bay the 10 points needed to secure victory. The loss of star WR Mike Evans (hamstring) hasn't hampered Mayfield and the passing offense, as the signal-caller is averaging 334.0 passing yards with a pair of touchdowns in the two games sans Evans. Mayfield will look to build off of the momentum of his cleanest outing when the Buccaneers host the 49ers next Sunday.

DeVito (coach's decision) is inactive for Sunday's game against the Bills and will serve as the emergency third quarterback.

As the emergency third quarterback, DeVito will not be allowed to see the field unless Drake Maye and Joshua Dobbs were to leave the game due to injury, illness or ejection.

Jones completed 20 of 29 passes for 212 yards with two touchdowns and no interceptions and added one rush for two yards in the Colts' 40-6 win over the Raiders on Sunday. He also committed a fumble recovered by Indianapolis.

Jones' solid, efficient stat line was a fitting microcosm of what's come to define his body of work early in his Colts tenure, as the veteran signal-caller once again turned in a mistake-free effort that complemented the exploits of Jonathan Taylor and the defense perfectly. Jones worked with a tight circle of five targets overall, tossing his pair of touchdowns to Tyler Warren (11 yards) and Michael Pittman (four yards). Jones has completed a sharp 71.3 percent of his passes and posted a 6:2 TD:INT through his first five games at the helm of Indianapolis' offense, and he's added another three scores on the ground. Jones next takes aim at the Cardinals' defense in a Week 6 home clash.

Murray (foot) returned to Sunday's game versus the Titans, Adam Schefter of ESPN reports.

Murray made a brief exit in the third quarter due to a foot injury but was able to get back on the field in short order. He'll look to build upon the 194 yards on 19-for-25 passing and 25 yards and a TD on four carries that he'd put together at the time of his departure.

Murray sustained a foot injury during Sunday's game against the Titans, Tyler Drake of ArizonaSports.com reports.

Murray walked to the locker room in the third quarter after bungling a snap off his facemask that resulted in a lost fumble. Jacoby Brissett will direct the Cardinals offense for as long as Murray is sidelined. At the time of his exit, Murray had completed 19 of 25 passes for 194 yards, no touchdowns and no interceptions and rushed four times for 25 yards and one TD.

Stroud completed 23 of 27 passes for 244 yards, four touchdowns and no interceptions in Sunday's 44-10 win over the Ravens. He added one rush for 30 yards.

Stroud faced a thinned version of the Baltimore defense that was missing Kyle Hamilton (groin), Marlon Humphrey (calf) and Chidobe Awuzie (hamstring) in its secondary alone. He took advantage of the good spot, throwing more than three touchdowns for only the second time in his career while completing three passes of at least 20 yards. Stroud was ultimately pulled early in the fourth quarter due to the game being a blowout, but it was a positive fantasy performance and also a good showing for the Houston offense overall.

Rush completed 14 of 20 passes for 179 yards, no touchdowns and three interceptions in Sunday's 44-10 loss to the Texans.

Rush led the Ravens on a decent first drive that resulted in a field goal, completing all five of his pass attempts for 59 yards. Things imploded from there, however, as the Ravens turned in consecutive three-and-outs to end the first half before Rush threw three picks in the final two quarters. The one positive is that Rush was able to complete a long pass to Zay Flowers, salvaging the star receiver's fantasy day. Rush could be lined up for a Week 6 start against the Rams, pending Lamar Jackson's (hamstring) recovery.

Hurts completed 23 of 38 passes for 280 yards with two touchdowns and no interceptions and added two rushes for three yards in the Eagles' 21-17 loss to the Broncos on Sunday.

Despite the Broncos' standout secondary and the fact they held a lead for a significant portion of the game, the Eagles curiously took a pass-centric approach Sunday, affording Saquon Barkley a scant six carries. Hurts recorded season highs in completions, pass attempts and passing yards, while also recording multiple touchdown tosses for the third consecutive game by connecting with Dallas Goedert (two yards) and Barkley (47 yards) in the second and third quarters, respectively. However, Hurts also took a season-high six sacks, and he threw incomplete on back-to-back plays from the Broncos' 29-yard line to finish the game. Hurts was also much less involved than usual as a runner, but he draws an excellent matchup on a short week when the Eagles visit the Giants on Thursday night to kick off Week 6.

Prescott completed 18 of 29 passes for 237 yards and four touchdowns in Sunday's 37-22 win over the Jets. He added 28 rushing yards on seven carries.

For the second straight game, Prescott chucked multiple TDs without having CeeDee Lamb (ankle) on the field, this time hitting Jake Ferguson twice and George Pickens and Javonte Williams once each. Prescott has a 7:0 TD:INT over the last two contests, and Sunday's performance may have been even more impressive considering four of the Cowboys' five starting offensive linemen were sidelined. The veteran QB figures to keep rolling in Week 6 against a Panthers defense that just gave up three passing TDs to Tua Tagovailoa.

Dart completed 26 of 40 passes for 202 yards and two touchdowns with two interceptions in Sunday's 26-14 loss to the Saints. He added 55 rushing yards on seven carries and also lost a fumble.

The rookie's second career NFL start didn't go as well as his first, as Dart put the ball on the ground in the third quarter with his team down only 16-14, and then threw two picks in the fourth quarter while trying to mount a comeback. Dart leaned heavily on short routes in his first game working without Malik Nabers (knee), with tight end Theo Johnson catching both his TDs and Johnson, No. 2 tight end Daniel Bellinger and running back Cam Skattebo combining for 16 receptions. Dart will need to clean up his turnovers in Week 6 if the Giants are going to have any hope of upsetting the NFC East-leading Eagles.