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Caleb Williams QB | CHI
Bears' Caleb Williams: Won't practice Wednesday
Coach Ben Johnson said Williams (hamstring) won't take part in Wednesday's practice, Courtney Cronin of ESPN reports.
Because the Bears play on Monday Night Football in Week 3, they won't be filing an official injury report until Thursday, but when it comes to Wednesday's unofficial session, both Williams and No. 2 QB Tyson Bagent (concussion) will be non-participants. Williams' lack of on-field work in the wake of the strained right hamstring that he suffered this past Sunday against the Vikings doesn't come as a surprise, but Johnson relayed to Sean Hammond of the Chicago Tribune that he hasn't ruled out Williams from playing Monday against the Eagles. In the end, Case Keenum is the healthiest signal-caller on Chicago's active roster and seems the best bet to get the nod under center this week.
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Jayden Daniels QB | WAS
Commanders' Jayden Daniels: Out for Week 3, set for more tests
Commanders head coach Dan Quinn confirmed that Daniels will be out for Sunday's game against the Seahawks, but the quarterback remains without a precise timeline for a return while he continues to receive more medical opinions on his left elbow injury, Ben Standig of The Team 980 Washington D.C. reports.
Per Zach Selby of the Commanders' official site, Daniels is set to meet with another arm specialist Wednesday, and the team isn't expected to provide a formal timeline until the quarterback concludes the information-gathering process for his dislocated left elbow. Marcus Mariota will direct the Washington offense in Week 3, and he could be in line for additional starts beyond that if Daniels needs more extended time to recover from his injury. After dislocating the same elbow last November, Daniels missed four weeks, then was shut down for the season after aggravating the injury in his first game back in action.
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Jaxson Dart QB | NYG
Giants' Jaxson Dart: Set for season-ending surgery
Dart is expected to undergo knee surgery that will end his 2026 season but lead to a full recovery heading into 2027, Ian Rapoport and Mike Garafolo of NFL Network report.
According to Adam Schefter of ESPN, medical tests on Dart's left knee have revealed that his ACL is intact, but the second-year quarterback sustained damage to his MCL, PCL and meniscus after taking a big hit from two defenders on the Giants' seventh play of Monday's 28-6 loss to the Rams. Schefter adds that the meniscus is the primary concern for Dart, who was initially believed to have sustained only an MCL sprain before follow-up tests showed more damage than anticipated. With surgery on tap for Dart, the Giants will move forward with Jameis Winston as their new starting quarterback beginning with this Sunday's game against the Titans.
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Mac Jones QB | SF
49ers' Mac Jones: Sees limited action in Week 2
Jones did not attempt a pass and lost two yards on two end-of-game kneel-down plays during Sunday's 35-13 victory over the Dolphins.
The 49ers had no trouble building a comfortable lead throughout the contest, leading to Jones coming in to mop up over the final two series. The 28-year-old is coming off a sound 2025 campaign, throwing for 2,151 yards, 13 touchdowns and six interceptions while completing a career-best 69.6 percent of his attempts. While Jones is considered one of the better backup quarterbacks in the NFL, his fantasy ceiling is virtually non-existent as long as Brock Purdy is healthy.
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Bailey Zappe QB | NYJ
Bailey Zappe: Replaced by Levis on practice squad
The Jets cut Zappe from the practice squad Tuesday, Eric Allen of the team's official site reports.
Zappe lost out to Cade Klubnik for a spot on the 53-man roster at the end of training camp, and the former's short tenure with the Jets is over after the team signed Will Levis to the practice squad. Zappe has appeared in 15 regular-season games (nine starts) since 2022 and should catch on with a team in need of quarterback depth on the practice squad.
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Sam Darnold QB | SEA
Seahawks' Sam Darnold: Will practice Wednesday
Darnold (glute) will practice Wednesday, according to Ian Rapoport of NFL Network.
The Seahawks quarterback has been trending toward a quicker return than initially expected after coach Mike Macdonald said Sunday that Darnold was ahead of schedule in his recovery. With the QB set to get back on the practice field, he hasn't yet been ruled out for Week 3 against Washington. Darnold's level of practice participation during the week should provide more clarity on whether he's on track to return Sunday, or whether Drew Lock will be in line for another start.
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Tua Tagovailoa QB | ATL
Falcons' Tua Tagovailoa: Turns in full practice
Tagovailoa (oblique) was a full participant in Tuesday's practice, Tori McElhaney of the team's official site reports.
Tagovailoa took part in his first full practice since Sept. 9, after he sustained an oblique injury a day later that kept him from playing in either of the Falcons' first two games of the season. The 28-year-old had been poised to direct the offense in Week 1, but he'll now have to settle for the No. 2 role with Michael Penix (knee) getting cleared to make his 2026 debut as the team's starting quarterback Thursday versus the Packers.
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Case Keenum QB | CHI
Bears' Case Keenum: Could get Week 3 start
Keenum could start Monday's game against the Eagles with both Caleb Williams (hamstring) and Tyson Bagent (concussion) potentially unavailable, Courtney Cronin of ESPN.com reports.
A healthy inactive as the emergency No. 3 quarterback in the Bears' 9-3 loss to the Vikings this past Sunday, Keenum may suddenly be called upon to make his first NFL start since 2023. Head coach Ben Johnson noted Monday that he didn't expect Williams to practice this week but wasn't willing to officially rule him out yet from playing against the Eagles. That would line Bagent up to receive all the first-team reps in practice, but his surprise placement in the NFL's five-step concussion protocol Tuesday puts him at risk of joining Williams in street clothes in Week 3. While he represents an experienced fallback plan, the 38-year-old Keenum would likely be limited to a game-manager role as a starter, which could hinder the fantasy prospects of the Bears' pass catchers but lead to increased volume for running backs D'Andre Swift and Kyle Monangai.
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Jameis Winston QB | NYG
Giants' Jameis Winston: Extended starting opportunity awaits
Winston could be in line for an extended run as the Giants' starting quarterback after Jaxson Dart sustained a more serious knee injury than anticipated in Monday's 28-6 loss to the Rams, Ian Rapoport and Mike Garafolo of NFL Network report.
After exiting in the first quarter Monday, Dart received a preliminary diagnosis of a sprained MCL, an injury that typically entails a multi-week absence. Unfortunately for Dart, follow-up tests Tuesday seemingly revealed additional damage to his knee that could potentially lead to season-ending surgery. Dart will likely receive additional medical opinions before a treatment plan and recovery timeline is established, but with an extended absence on tap, the door is open for Winston to direct the New York offense beginning with Sunday's game versus Tennessee. Winston averaged a healthy 8.6 yards per attempt between two starts and one brief appearance off the bench with the Giants a season ago, but he was highly inefficient in relief of Dart in his 2026 debut Monday, completing just 11 of 27 passes for 111 yards, no touchdowns and an interception.
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Jaxson Dart QB | NYG
Giants' Jaxson Dart: May need season-ending surgery
Dart is facing the possibility of season-ending surgery after further testing Tuesday revealed that the left knee injury he sustained in Monday's 28-6 loss to the Rams is worse than originally anticipated, Adam Schefter of ESPN reports.
The Giants had previously been optimistic that Dart would avoid an extended absence after initial scans following Monday's game suggested that he sustained an MCL sprain in his knee, but follow-up tests appear to have revealed more significant damage. Dart is likely to seek out additional medical opinions before deciding on a treatment plan for his injury, but if surgery is deemed necessary, he would likely be lost for the remainder of the 2026 campaign. Jameis Winston is poised to direct the Giants offense in Week 3 versus the Titans and could be in line for an extended run as the team's starting quarterback.