NFL Player News

Coach Kyle Shanahan hopes Wilson (calf) can return to practice Wednesday, Matt Barrows of The Athletic reports.

With Tevin Coleman (knee) unlikely to be activated from IR this week and Raheem Mostert about to join him due to a high left ankle sprain, Wilson would be in line for more touches when he can get past the calf injury that kept him in street clothes Sunday versus the Rams. If he participates in Wednesday's session, it'll mark Wilson's first non-DNP since last Wednesday's injury report. Elsewhere in the 49ers backfield, Jerick McKinnon and JaMycal Hasty are the only healthy bodies.

Coach Kyle Shanahan told Nick Wagoner of ESPN.com that Mostert has been diagnosed with a high left ankle sprain and "most likely" will be placed on injured reserve.

Mostert sat out Weeks 3 and 4 with a sprained MCL and now is poised to miss at least three more games due to the ankle issue that forced him out of Sunday's win against the Rams. Shanahan also mentioned Tevin Coleman (knee) is a "long shot" to be activated from IR this week, per Matt Barrows of The Athletic, leaving Jerick McKinnon, JaMycal Hasty and Jeff Wilson (calf) as the likely running backs available to the 49ers offense this coming Sunday at New England.

Akers played just a single snap during Sunday's 24-16 loss to San Francisco.

After head coach Sean McVay suggested the rookie was in line for an increased workload, Akers played a single snap Sunday and didn't touch the football. It was a bit surprising, but Los Angeles only had possession for 8:37 in the first half, and No. 1 back Darrell Henderson rushed just six times. The Rams never had an opportunity to find the offensive rhythm to enable them to turn to Akers. Making matters worse, Henderson impressed again with 14 rushes for 88 yards, and veteran running back Malcolm Brown looks locked into a consistent role as a trusted pass protector. While Akers remains an intriguing long-term fantasy asset, he's also far from a reliable option at this stage of the campaign.

Abdullah had two carries for seven yards and one reception for one yard on two targets in Sunday's loss to the Falcons. He also added three kick returns for an average of 24.3 yards.

Abdullah played on 16 of the offense's 56 snaps as he got more playing time than Mike Boone (five snaps) as Alexander Mattison's backup with Dalvin Cook sidelined with a groin injury with the Vikings needing to throw the ball after falling behind big early. Abdullah will likely return to a minimal role with Cook expected to return after Minnesota's Week 7 bye.

Boone lost a yard on his only carry in Sunday's loss to Atlanta, a critical loss on a fourth-and-goal play.

Boone played on just five of the offense's 56 snaps as Ameer Abdullah (16 snaps) got more playing time as Alexander Mattison's backup with Dalvin Cook sidelined with a groin injury. Abdullah is used more in the passing game, and the Vikings were playing from behind a large deficit most of the game. Boone likely will return to a minimal role with Cook expected to return after Minnesota's Week 7 bye.

Wilkins lost a yard on his only carry and didn't make a reception on the only pass targeted his direction in Sunday's win over the Bengals.

With the Colts needing to make up a large deficit early in the game, Indy turned to the passing game and Wilkins was largely out of the game plan. Wilkins had just four snaps on offense with Nyheim Hines getting 21 snaps. Wilkins gets more playing time when the Colts need someone to give Johnathan Taylor relief when running the ball, with Hines more involved in the passing game.

Hines had five receptions on six targets for 27 yards in Sunday's win over the Bengals.

Hines played 21 snaps on offense compared to just four snaps for Jordan Wilkins as the Colts turned to the passing game after falling behind early. Hines should continue to get more work as Jonathan Taylor's backup when the Colts need to pass, with Wilkins used more when Taylor needs a break carrying the ball.

Clement failed to corral his lone target in Sunday's 30-28 loss to the Ravens.

Clement played seven offensive snaps in the contest, his most since the Eagles' Week 1 loss to Washington, when Miles Sanders was sidelined with a hamstring injury. Sanders exited Sunday's contest midway through the third quarter with a knee injury that's expected to keep him out for 1-to-2 weeks, paving the way for Clement to see a slightly expanded workload Week 7 in a Thursday night matchup with the Giants. That said, Boston Scott is likely to operate as the lead option in the Eagles' backfield committee while Sanders is out, so Clement probably can't be counted on to take on double-digit touches if the game proves to be reasonably competitive throughout.

Moss (toe) is active for Monday's game against the Chiefs.

Moss, who last suited up Week 2, will return to the Bills' backfield mix Week 6 and is set to work in tandem with Devin Singletary on Monday, with the team having deactivated T.J. Yeldon for the contest.

Coach Doug Pederson said that the Eagles would likely use a running-back-by-committee Thursday against the Giants if starter Miles Sanders (knee) is unavailable, with Scott presumably stepping in as the lead option, Tim McManus of ESPN.com reports.

Sanders exited Sunday's loss to the Ravens with a knee injury, and while the Eagles are still waiting on the results of an MRI before confirming his status for Thursday's divisional game, Chris Mortensen of ESPN relays that the 23-year-old is expected to be sidelined for 1-to-2 weeks. After Sanders left the Week 6 contest following his 74-yard run midway through the third quarter, Scott out-touched the Eagles' other active running back, Corey Clement, by a 5-0 margin, though Clement had a reception nullified by a penalty. With that in mind, Scott profiles as the top candidate to absorb the bulk of Sanders' work, likely leaving Scott and Jason Huntley to handle smaller supporting roles as part of a committee.