NFL Player News

Jacobs (shoulder) was listed as a limited participant at Wednesday's practice.

Jacobs played through his shoulder issue in Sunday's loss to the Texans, leading the Raiders backfield with 15 carries for 66 yards and two catches for 15 yards. With no reported setbacks in that contest, his limitations Wednesday were likely maintenance-related.

Zenner will be a part of a "running back by committee" Thursday versus the 49ers, Darren Urban of the Cardinals' official site reports.

Although the team has ruled out Chase Edmonds (hamstring), No. 1 back David Johnson is considered questionable due to his lingering ankle injury. If coach Kliff Kingsbury opts to hold Johnson out for a second game in a row, Zenner is expected to rotate in with newcomer Kenyan Drake and Alfred Morris. In his first appearance with the Cardinals in the Week 8 loss to New Orleans, Zenner notched one carry for zero yards and one reception (on one target) for 13 yards while playing 19 offensive snaps.

Drake will be a part of the offense Thursday against the 49ers with David Johnson (ankle) listed as questionable and Chase Edmonds (hamstring) ruled out for the contest, Darren Urban of the Cardinals' official site reports. "We're going to get him in the game in some packages," coach Kliff Kingsbury said of Drake.

Dealt from Miami on Monday, Drake hasn't had much time to acclimate to Arizona's scheme, but with a need out of the backfield, Kingsbury has given assurances the newcomer will play a role in his first chance to do so. His snap count may depend on the availability of Johnson, who returned to the practice field Wednesday for the first time since Oct. 18. If Johnson ultimately is deemed inactive Thursday, Drake will be in a "running back by committee" with Zach Zenner and Alfred Morris.

Mostert (knee) is listed as questionable for Thursday's game in Arizona.

Mostert and Matt Breida (ankle) followed the same regimen this week, practicing in a limited capacity Monday and Wednesday while sitting out Tuesday's walkthrough at Levi's Stadium. Both running backs are questionable, which could allow Jeff Wilson to serve as the No. 2 behind top option Tevin Coleman.

Breida (ankle) is listed as questionable for Thursday's game at Arizona, Eric Branch of the San Francisco Chronicle reports.

Brieda managed only two limited practices this week due to the tender ankle, but that might be enough for him to earn an active status once Thursday arrives. If so, he likely will be limited behind lead back Tevin Coleman, especially with fellow reserve Jeff Wilson healthy at the moment. The 49ers will release their list of inactives about 90 minutes before Thursday's 8:20 p.m. ET kickoff.

Edmonds (hamstring) has been ruled out for Thursday's game against the 49ers, Josh Weinfuss of ESPN.com reports.

Edmonds is nursing a hamstring injury that could sideline him for multiple weeks, so his absence Thursday doesn't come as much of a surprise. With the status of No. 1 running back David Johnson (ankle) still up in the air, Arizona's backfield may consist of Kenyan Drake, Zach Zenner and Alfred Morris in Week 9.

Snell (knee) didn't practice Wednesday.

Top back James Conner (shoulder) also didn't practice Wednesday, but Jaylen Samuels -- now recovered from a knee scope -- was able to practice fully and has been declared ready to return to action Sunday against the Colts, per Brooke Pryor of ESPN.com. If Snell is able to play Sunday against the Colts, he would work in a complementary role behind Conner (if available) and/or Samuels.

Sanders (shoulder) said that he expects to suit up for Sunday's game against the Bears, Les Bowen of the Philadelphia Daily News reports.

Sanders was unable to practice Wednesday, but noted that he'll likely be back on the field for Thursday's session in some capacity. During Sunday's win over the Bills, the rookie running back reportedly aggravated a shoulder injury that dates back to his time at Penn State. While it's certainly good news that the 22-year-old has avoided a significant injury, the Eagles could take a cautious approach with him ahead of a Week 10 bye. If Sanders ends up sitting against the Bears, Darren Sproles (quadriceps) -- if cleared to play -- and Boston Scott would be candidates for change-of-pace roles behind Jordan Howard.

Conner (shoulder) didn't practice Wednesday.

The same applies to Benny Snell (knee), while Jaylen Samuels (knee) -- who didn't play in Monday's win over the Dolphins -- practiced fully Wednesday. Per Brooke Pryor of ESPN.com, Conner is dealing with an AC joint injury in his right shoulder, which puts his Week 9 status up in the air for now. If Conner is out or limited this weekend against the Colts, Samuels would be in line to see an expanded role on offense.

McCaffrey was limited at Wednesday's practice due to a knee injury, Jourdan Rodrigue of The Athletic reports.

After the session, coach Ron Rivera expressed "no concern" about McCaffrey's health, according to Rodrigue. It still bears watching as the week goes on, but there doesn't seem to be much worry about McCaffrey's availability for Sunday's game against the Titans.