Herbert rushed twice for five yards and didn't catch his only target in Sunday's 42-10 loss to the Patriots.

Top two running backs Breece Hall (knee) and Isaiah Davis (concussion) exited in the second half, but Kene Nwangwu finished with six carries to Herbert's two. Both depth options could play expanded roles in Week 18 against the Bills if Hall and Davis are held out.

Nwangwu rushed six times for 31 yards and wasn't targeted in Sunday's 42-10 loss to the Patriots. He also returned four kickoffs for 114 yards.

Breece Hall (knee) and Isaiah Davis (concussion) both exited in the second half, opening the door for Nwangwu and Khalil Herbert to take on larger roles. Nwangwu's contributions are usually limited to special teams, and Sunday's six carries marked a new career high for the 27-year-old running back. He could see an expanded role again in Week 18 against the Bills if Hall and Davis aren't available.

Ali had two catches for eight yards on three targets Saturday against the Packers.

Ali was shut out of the rushing rotation Saturday as Derrick Henry and Keaton Mitchell took all the carries among running backs. He had three targets, though, which was a respectable share considering Baltimore only threw the ball 20 times. Ali seems to have carved out a role as a pass-catching specialist out of the backfield, but he has just six carries for 24 yards on the season.

Williams had two carries for 10 yards in Sunday's 13-6 win over the Steelers in Week 17. He also returned one kickoff for 25 yards.

Dylan Sampson's return from an ankle injury left Williams has the third back behind Sampson and Raheim Sanders. Williams was added to Cleveland's 53-man roster a few weeks ago, while the Browns coped with injuries, and he has carved out a minor role in the backfield. The most significant of those injuries was to Quinshon Judkins (ankle/leg) last week, but with everyone else healthy, Williams isn't likely to see a much bigger workload in Week 18 against the Bengals.

Spears rushed the ball six times for two yards in Sunday's 34-26 loss to the Saints. He added one reception on two targets for minus-2 yards.

Spears saw a significant uptick in usage in Week 16 and tallied 105 yards from scrimmage. However, he returned to a complementary role in Week 17, earning only seven touches compared to 20 for Tony Pollard. Spears was also shut down as both a rusher and receiver, and he's now been held below five rushing yards in four of his last seven games.

Monangai handled eight carries for 38 yards and caught three of four targets for nine yards in Sunday's 42-38 loss to the 49ers.

Monangai and D'Andre Swift (9-54-2) both averaged well over 4.0 yards per carry against the 49ers' porous run defense Sunday, but the latter's pair of rushing touchdowns gave the veteran counterpart of Chicago's backfield duo the fantasy edge in Week 17. Monangai has cooled off a bit since exploding on the scene midseason, averaging 44.5 rushing yards per game with no touchdowns over his last four contests. That said, the seventh-round rookie remains a featured piece on offense for Chicago heading into a Week 18 matchup against the Lions.

Swift took nine carries for 54 yards and a pair of touchdowns while adding two receptions on three targets for 25 yards in Sunday's 42-38 loss to the 49ers.

Swift actually finished with fewer carries and less yardage than in his quiet fantasy outing against the Packers in Week 16, but he was able to do far more with less against the 49ers on Sunday Night Football. The 26-year-old averaged 6.0 yards per carry while scoring multiple rushing touchdowns for the second time over his last three starts. Swift and backfield mate Kyle Monangai (11 touches for 47 yards) split work evenly as they have been doing for most of the season, with the veteran outshining the rookie this time around. Fantasy managers can confidently start both of Chicago's talented backs in the regular-season finale against the Lions.

McCaffrey took 23 carries for 140 yards and a touchdown while corralling four of six targets for 41 yards in Sunday's 42-38 win over the Bears.

McCaffrey shouldered a heavier load on offense with star TE George Kittle (ankle) missing in action Sunday, resulting in a season-high 140 rushing yards from CMC. The 29-year-old's scamper to the end zone in the second quarter brought him up to an even 10 rushing scores on the year. McCaffrey has reached double-digit rushing touchdowns three times in his storied career, accomplishing the feat twice as a member of the 49ers. The versatile tailback's modest receiving totals on SNF puts a potential 1,000-1,000 season in jeopardy, as he would need 110 receiving yards in Week 18 in order to accomplish the incredible feat for the second time in his career. Fantasy managers should expect a heavy dose of the fantasy stud against the Seahawks with the NFC's No. 1 seed and a first-round bye on the line in the regular-season finale.

Sampson rushed the ball 11 times for 27 yards in Sunday's 13-6 win over the Steelers. He added three receptions on three targets for zero yards.

Sampson was able to return from a two-game absence, and he immediately led Cleveland's backfield with 14 touches. That translated to limited production, as he was inefficient as both a rusher and receiver. However, Sampson will likely retain a significant role for a more favorable Week 18 matchup against the Bengals.

Sanders rushed the ball eight times for 21 yards in Sunday's 13-6 win over the Steelers. He added one reception on two targets for 10 yards.

Sanders worked closely behind Dylan Sampson in the Cleveland backfield, logging nine touches to Sampson's 14. Sanders was unable to get much going on the ground, with his longest rush going for only six yards. He should maintain a split in the Browns' backfield heading into a Week 18 matchup against the Bengals, though his fantasy appeal remains minimal.