NFL Player News

With CeeDee Lamb (quadriceps) healthy and cleared to play Sunday night against the Packers, Pickens will handle his normal role as Dallas' WR2.

Lamb exploded for 17 catches in Week 4, but the Cowboys made a concerted effort to get Pickens more involved last Thursday night against the Bucs, as he secured nine of 13 targets for 130 yards and a touchdown. Lamb suffered a quad bruise late in the game, and it allowed Pickens to be the clear WR1 and target hog while Lamb nursed his injury on the sideline. Pickens has weekly monster box-score upside, and he can still go off for a big line even with Lamb past his bruised thigh.

Harris (hamstring) has been ruled out for Sunday's game against the Chiefs.

Harris didn't practice this week, after making an early exit from the Week 5 loss to Denver. With Ladd McConkey (foot) and Quentin Johnston (chest) now returning from injuries, the team's WR room is in better shape than a week ago even without Harris.

Dulin (hamstring) has been ruled out ahead of Sunday's game against the Titans, Joel A. Erickson of The Indianapolis Star reports.

Dulin was unable to participate in any Week 6 prep sessions. The wide receiver will miss a second consecutive game as he focuses on recovering from his hamstring issue. Deion Burks is set to be the No. 4 wide receiver for the Colts again.

Kirk (calf) remained limited in Friday's practice, Harrison Rich of the San Francisco Chronicle reports.

Kirk had his 21-day practice window opened Thursday, as he's eyeing a potential return from injured reserve Monday night against the Commanders. The 49ers will make a decision on his potential activation Saturday, so there will be a better idea of his Week 6 availability in the next 24 hours. Kirk's return would be a boost to an injury-ravaged San Francisco wideout room.

Burks (shoulder) remained limited in Friday's practice.

Stefon Diggs (hamstring) upgraded to limited after being DNP on Thursday, and Terry McLaurin got a veteran's rest day after returning from his hamstring injury last Sunday. Burks caught two of five targets for 26 yards in last Sunday's 27-27 tie with the Giants.

Moore (ankle) has been ruled out for Sunday night's game against the Cowboys, Wes Hodkiewicz of the Packers' official site reports.

Moore was held out of practice all week due to an ankle injury that he picked up during the Packers' Week 5 win against the Bears. The injury is severe enough for him to be sidelined for Sunday's game, so Bo Melton, Kaleb Johnson and Matthew Golden figure to be the top candidates to take over return duties on kickoffs and punts. Moore's next opportunity to play is Week 7 against the Lions on Sunday, Oct. 25.

Evans (ribs/Achilles) was a non-participant at Friday's practice, Harrison Rich of the San Francisco Chronicle reports.

Evans was spotted working on the side at the start of Friday's session, but with no activity for a second day in a row, he now has just one more chance to mix into drills Saturday before the 49ers potentially tag him with a designation ahead of Monday's game against the Commanders. There's more cause for concern this week due to the 49ers adding 'Achilles' next to his name on the injury report, and head coach Kyle Shanahan has termed the new issue "soreness," according to Nick Wagoner of ESPN.com.

Diggs (hamstring) was limited at Friday's practice.

This marks Diggs' first notable on-field work since Week 4 prep as he deals with a hamstring injury, which held him out of a Week 5 tie with the Giants. Both Diggs and No. 1 WR Terry McLaurin (hamstring), who was given a veteran's rest day Friday, are tending to health concerns at the moment, and Saturday's practice likely will be key to determine if either of them get designations for Monday's game in San Francisco.

Thornton (hamstring) won't be activated from injured reserve for Sunday's game against the Bills, Sam Warren of The Athletic reports.

Thornton has been a full practice participant for two weeks, and he can practice for one more week before the Raiders have to make a decision on activating him from IR or leaving him there for the rest of the year. He'll likely be activated, but it isn't clear there's a role for him in the offense.

Nailor (concussion) doesn't have an injury designation for Sunday's game at Las Vegas, Sam Warren of The Athletic reports.

Nailor cleared concussion protocol after missing a Week 5 loss to the Patriots. He hasn't done much with his routes this year, but the lack of alternatives in Las Vegas should keep him in a role as the No. 2 or 3 wide receiver. Cody White has made a case for more playing time in recent weeks, benefitting from red-zone usage and then Nailor's absence.