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Ben Yurosek TE | MIN
Vikings' Ben Yurosek: Tagged as questionable vs. New Orleans
Yurosek (ankle) is listed as questionable for Sunday's game against the Saints.
Yurosek opened the regular season on injured reserve due to an ankle injury. His 21-day window to return from IR opened Wednesday, and while he's tagged as questionable for Sunday's NFC North showdown, the positive news is that Yurosek was a full participant in all three practices during Week 5 prep. If he's cleared to make his 2026 regular-season debut, then he would operate alongside Gavin Bartholomew in a rotational role at tight end behind starter T.J. Hockenson.
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Andrew Wingard SAF | ARI
Cardinals' Andrew Wingard: Won't play against Detroit
Wingard (knee) has been ruled out for Sunday's game against the Lions, Bo Brack of GoPHNX.com reports.
Wingard was held out of practice all week due to a bone bruise in his knee, which he sustained against the Giants in Week 4. Wydett Williams figures to start alongside Budda Baker at safety due to the absence of Wingard, whose next chance to play is Week 6 against the Rams on Sunday, Oct. 18.
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Francisco Mauigoa LB | NYJ
Jets' Kiko Mauigoa: Won't play against Cleveland
Mauigoa (quadriceps) has been ruled out for Sunday's game against the Browns, Brian Costello of the New York Post reports.
Mauigoa was held out of practice all week due to a quadriceps injury, which will force him to miss a third consecutive game. Jamien Sherwood and Demario Davis will continue to operate as the Jets' starting linebackers in the absence of Mauigoa, whose next chance to play is Week 6 against the Patriots on Sunday, Oct. 18.
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Savion Williams WR | GB
Packers' Savion Williams: Will stay on IR for Week 5
Williams (ankle) has been ruled out for Sunday's game against the Bears, Wes Hodkiewicz of the Packers' official site reports.
Williams opened the regular season on IR due to a high-ankle sprain that he suffered late in training camp. He was designated to return from IR on Wednesday and was a limited participant in practice all week, and while the second-year wideout is not yet quite ready to make his 2026 regular-season debut, his next chance to do so is Week 6 against the Cowboys on Sunday, Oct. 18. Williams would be in line for WR3 duties behind Matthew Golden and Christian Watson in his return, given the fact that Jayden Reed (neck, IR) is out for the rest of 2026.
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George Holani RB | SEA
Seahawks' George Holani: Tagged as questionable for Week 5
Holani (ribs/knee) is listed as questionable for Sunday's game against the 49ers, Bob Condotta of The Seattle Times reports.
A rib injury limited Holani's practice participation all week, and he's now working through a knee issue that popped up on Friday's injury report. Emanuel Wilson has stepped into the RB1 role in the absence of Jadarian Price (chest, IR), and if Holani is not cleared to play, then Velus Jones and Robert Henry would be in line for larger rotational roles out of the backfield behind Wilson.
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Tre Harris WR | LAC
Chargers' Tre' Harris: Set to be Bolts' WR1 against Denver
Harris' workload should be larger against the Broncos on Sunday, as Quentin Johnston (chest) has been ruled out and Ladd McConkey (foot, questionable) may not play, Alex Insdorf of BoltBeat.com reports.
Rookie fourth-rounder Brenen Thompson (quadriceps) has also been ruled out alongside Johnston. McConkey faces an uphill battle to play Sunday after sitting out of practice all week, and he may operate under a snap count if he's given the green light to suit up. That puts Harris -- who has seen five targets or more in three of four games this season -- in position to work in an elevated role against a Broncos defense that will be without both starting outside cornerbacks Riley Moss (ribs) and Patrick Surtain (ankle).
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Pat Bryant WR | DEN
Broncos' Pat Bryant: Officially placed on IR
Bryant (ankle) was placed on the Broncos' injured reserve Friday.
Because of his placement on IR due to an ankle injury, Bryant will be required to miss at least the next four games. The earliest he can return is Week 9 against the Panthers, but with the Broncos on bye for Week 10, the second-year wide receiver could be held out until Week 11 against the Raiders in late November. Troy Franklin figures to step into the WR3 role behind Courtland Sutton and Jaylen Waddle for as long as Bryant is sidelined.
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Mason Taylor TE | NYJ
Jets' Mason Taylor: Green light to return for Week 5
Taylor (thumb) does not carry an injury designation into Sunday's game against the Browns, Daniel Oyefusi of ESPN.com reports.
Taylor strung together a trio of full practices, and the second-year rookie has been cleared to return Sunday from a two-game absence due to a thumb injury. He saw just three targets through the first two games of the regular season, whereas rookie TE Kenyon Sadiq has turned 18 targets from QB Geno Smith into a 12-143-1 receiving line across four games. That said, both of the Jets tight ends could find success against a Browns defense that ranks in the bottom-10 in the league in fantasy points allowed to tight ends.
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Marcus Mariota QB | WAS
Commanders' Marcus Mariota: Won't suit up for Week 5
Mariota (knee) has been ruled out for Sunday's game against the Giants.
Mariota was held out of practice all week while recovering from a right knee injury that he aggravated against the Colts in Week 4. The good news for the Commanders is that Jayden Daniels (left elbow) has been cleared to return for Week 5, and with Mariota sidelined, rookie seventh-rounder Athan Kaliakmanis will operate as the backup QB behind Daniels. The next opportunity for Mariota to return is Week 6 against the 49ers on Monday, Oct. 19.
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Rachaad White RB | WAS
Commanders' Rachaad White: Officially cleared for Week 5
White (shoulder) does not carry an injury designation ahead of Sunday's game against the Giants.
A shoulder injury prevented White from playing against the Colts in Week 4, but the fifth-year running back has been cleared to return for Week 5 after logging three consecutive limited practices. Jacory Croskey-Merritt (groin) has also been cleared to play Sunday, so White and Austin Ekeler both figure to operate in rotational roles out of the backfield.