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Darius Cooper WR | PHI
Eagles' Darius Cooper: Another touchdown in Week 5
Cooper caught two of three targets for 71 yards and a touchdown during Sunday's 19-17 loss to the Jaguars.
Cooper was able to reach paydirt again Sunday, securing a 62-yard touchdown on a deep pass from quarterback Jalen Hurts in the second quarter. The wide receiver has taken advantage of a larger workload in the last two weeks with DeVonta Smith (hamstring) sidelined, reeling in five of 10 targets for 104 yards and three touchdowns in Smith's absence. On the year, Cooper has caught seven of 13 targets for 137 yards and four scores over five contests.
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Sam LaPorta TE | DET
Lions' Sam LaPorta: Leads air attack in lopsided victory
LaPorta brought in all five of his targets for 88 yards and a touchdown in the Lions' 45-21 win over the Cardinals on Sunday.
The athletic tight end was a constant presence in the air attack during the high-scoring victory, and he finished with a season-high yardage total that also set the pace for the Lions on the afternoon. LaPorta also contributed his third touchdown of the campaign -- and his second in as many games -- with a 38-yard grab in the second quarter. LaPorta has his two highest yardage tallies of the season in the last two games, which affords him plenty of momentum heading into the Week 6 bye that precedes a Week 7 divisional showdown at home against the Packers on Sunday, Oct. 25.
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Jaylen Waddle WR | DEN
Broncos' Jaylen Waddle: Makes just two catches Sunday
Waddle corralled two of five targets for 19 yards and also had a nine-yard carry during Sunday's 23-17 road win against the Chargers.
Waddle has hit once (8-138-0 on 10 targets in Week 2 against the Jaguars) and otherwise hasn't done much (10-66-1 on 21 targets) in his other four appearances in his first campaign with the Broncos. It didn't help any of Denver's skill-position players that QB Bo Nix's 27 passes went for only 123 yards, and a quick turnaround to face the Seahawks defense Thursday isn't a recipe for Waddle or any of his teammates to turn around their fortunes to begin the 2026 season.
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Fernando Mendoza QB | LV
Raiders' Fernando Mendoza: Sees first NFL action in Week 5 loss
Mendoza completed six of eight passes for 48 yards without a touchdown or turnover in Sunday's 45-17 loss to the Patriots. He added three yards on his only carry.
With the game out of hand, Raiders coach Klint Kubiak elected to give Mendoza his first pro snaps on the team's final drive of the game, and the first overall pick in the 2026 draft acquitted himself well in a low-pressure situation, with his longest completion going for 16 yards to Tre Tucker. Mendoza even led Las Vegas into the red zone, but he came up just short on a fourth-and-4 from New England's 14-yard line as he scrambled for the sticks. It was only a matter of time until Mendoza replaced Kirk Cousins under center on a permanent basis, but a switch may not be imminent with the veteran QB having led the team to a 3-2 record. Mendoza has at least given his coach some early confidence that he'll be ready when the time comes.
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George Kittle TE | SF
49ers' George Kittle: Five short catches in Week 5 win
Kittle (illness) caught five of six targets for 24 yards in Sunday's 32-29 win over the Seahawks.
Kittle had an uncharacteristic third-down drop on San Francisco's opening drive but caught his other five targets to finish second on the 49ers in receiving yards despite playing through an illness. Mike Evans easily led the team with seven catches for 113 yards and a touchdown on 10 targets in Sunday's win. Kittle will have an extra day to recover before the Commanders come to town for Monday Night Football in Week 6.
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Emanuel Wilson RB | SEA
Seahawks' Emanuel Wilson: Posts TD, fumble on 22 touches
Wilson rushed 20 times for 61 yards and a touchdown in Sunday's 32-29 loss to the 49ers. He also caught both of his targets for 11 yards and lost a fumble.
Wilson followed up his two-touchdown performance in Week 4 against the Chargers with a two-yard rushing score in the first quarter against the 49ers, but he proceeded to lose a fumble in the second quarter. Fellow running back George Holani also lost a fumble and Sam Darnold threw two interceptions in a sloppy performance from Seattle's offense. Zach Charbonnet (knee) isn't expected to be activated from the reserve/PUP list ahead of Thursday's game against the Broncos, while Jadarian Price (chest) remains on IR, so Wilson is poised to remain Seattle's lead back in Week 6.
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Brock Purdy QB | SF
49ers' Brock Purdy: Tosses two TDs to improve to 5-0
Purdy completed 19 of 29 passes for 189 yards, two touchdowns and one interception in Sunday's 32-29 win over the Seahawks. He also rushed five times for six yards and threw a successful two-point conversion.
Seattle's talented defense made life tougher for Purdy than it had been up to this point, as he committed his first turnover since Week 1 and took his first three sacks of the season. Purdy nonetheless did enough to keep the 49ers undefeated. He threw a two-yard touchdown pass to Mike Evans in the first quarter and a seven-yard touchdown pass to Brandin Cooks in the fourth, the latter of which Purdy followed up with a two-point conversion to Evans. The Seahawks responded with a field goal to tie the game at 29-29, but Purdy led the 49ers into position for Eddy Pineiro's go-ahead 44-yard field goal with 1:56 remaining. San Francisco's defense delivered the game-winning stop as Purdy and the 49ers improved to 5-0 heading into a Week 6 MNF home game against the Commanders.
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Kirk Cousins QB | LV
Raiders' Kirk Cousins: Gives way to Mendoza late in rout
Cousins completed 19 of 28 passes for 243 yards and a touchdown in Sunday's 45-17 loss to the Patriots.
The lopsided result owed much more to the fact that the Raiders defense couldn't stop Drake Maye than it did to Cousins' performance, but it still provided coach Klint Kubiak with an opportunity to give Fernando Mendoza his first snaps in the NFL on the team's final drive. Las Vegas has lost two straight games with Cousins under center after a 3-0 start, and while the veteran QB has a more than respectable 12:4 TD:INT and 65.1 percent completion rate in his five starts, he was always going to be a placeholder until the first overall pick in the 2026 draft was deemed ready to take over. A switch at quarterback may not be imminent, but the clock is ticking on Cousins' tenure as the starter heading into a Week 6 battle with the Bills.
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Bo Nix QB | DEN
Broncos' Bo Nix: Switch in play callers falls flat
Nix was 16-for-27 passing for 123 yards, one touchdown and no interceptions, took four carries for 10 yards and fumbled twice (one lost) during Sunday's 23-17 victory at the Chargers.
With head coach Sean Payton taking over play-calling duties from offensive coordinator Davis Webb in Week 5, the decision didn't exactly light a fire under Nix and the Broncos offense. Nix settled for his fewest passing yards of the season, but he at least tossed a TD pass (to WR Courtland Sutton) for a fifth game in a row to kick off the campaign, giving him a 6:3 TD:INT so far. Nix may have a tough time producing better results on a short week when Denver hosts the defending champion Seahawks on Thursday night.
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Will Campbell OT | NE
Patriots' Will Campbell: Likely dealing with sprained knee
Campbell is believed to have suffered a sprained knee during Sunday's 45-17 win over Las Vegas, Ian Rapoport of NFL Network reports.
Campbell sustained the injury in the first half, and he will undergo an MRI on Monday to confirm the diagnosis. The 22-year-old will likely miss action moving forward, and in his absence, Caleb Lomu is a top candidate to fill in as the team's starting left tackle.