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Daniel Scott SAF | IND
Colts' Daniel Scott: Won't play against Las Vegas
Scott has been ruled out for Sunday's game against the Raiders due to a knee injury, James Boyd of The Athletic reports.
Scott was held out of practice all week due to a knee injury, and his next opportunity to play will be Week 6 against the Cardinals on Sunday, Oct. 12. He's mostly served on special teams, but in his absence, Rodney Thomas will serve as the top depth option at safety behind Nick Cross and Camryn Bynum.
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Christian Izien SAF | DET
Buccaneers' Christian Izien: Won't play at Seattle
Coach Todd Bowles said Friday that Izien (quadriceps) is out for Sunday's game against the Seahawks, Scott Smith of the Buccaneers' official site reports.
Izien will sit out for a second straight game as he continues to recover from a quad injury he picked up in Week 3 versus the Jets. In his absence, Kaevon Merriweather could see an uptick in reps in the secondary in Week 5.
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Tershawn Wharton DE | CAR
Panthers' Tershawn Wharton: Ruled out for Week 5
Wharton (toe) has been ruled out for Sunday's game against the Dolphins.
Wharton returned from a hamstring injury last Sunday against the Patriots and is now dealing with a toe issue that will cause him to miss his third game of the season. Jaden Crumedy should see elevated defensive snaps against Miami.
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Dorian Strong CB | BUF
Bills' Dorian Strong: Not playing vs. New England
Strong has been ruled out for Sunday's game against the Patriots due to a neck injury.
Strong was unable to participate in the last two practices of the week due to a neck injury, and the rookie sixth-rounder will miss his first game of the season as a result. Ja'Marcus Ingram and Cam Lewis are in line to see more rotational work at corner behind Tre'Davious White and Christian Benford due to Strong's absence. Strong will aim to return to practice next week and be available for the Bills' Week 6 road clash against the Falcons on Monday, Oct. 13.
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Shemar Stewart DE | CIN
Bengals' Shemar Stewart: Out for Week 5
Stewart (ankle) has been ruled out for Sunday's game against the Lions.
Stewart will miss his third consecutive game with the ankle injury. Myles Murphy has been seeing increased reps at edge rusher in Stewart's absence.
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Michael Jurgens G | MIN
Vikings' Michael Jurgens: Will not play Sunday
Jurgens (hamstring) has been ruled out for Sunday's game against the Browns.
With both Jurgens and starting center Ryan Kelly (concussion) out against Cleveland, Blake Brandel appears to be the next man up at the position.
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Ryan Kelly C | MIN
Vikings' Ryan Kelly: Ruled out for Week 5
Kelly (concussion) has been ruled out for Sunday's game against the Browns.
Kelly exited early last Sunday against the Steelers, and Michael Jurgens filled in at center, but Jurgens has also been ruled out against Cleveland due to a hamstring injury. Blake Brandel figures to draw the start in Week 5.
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John Ridgeway DT | NO
Saints' John Ridgeway: Questionable for Sunday vs. Giants
Ridgeway (shoulder) is officially listed as questionable for Sunday's game versus the Giants.
Ridgeway was a full participant at practice both Thursday and Friday, so he may be on the 'probable' end of the questionable designation. If he's able to suit up for the first time in 2025 in Week 5, he projects to fill a rotational role on the defensive line.
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Malik Turner WR | SF
Malik Turner: Goes back to practice squad
Turner reverted to the 49ers' practice squad Friday, per the NFL's transactions log.
Turner played just six of San Francisco's 86 offensive snaps Thursday, as Demarcus Robinson (73), Kendrick Bourne (70) and Marquez Valdes-Scantling (46) dominated in that category. With the 49ers still dealing with a ton of injuries at wide receiver, Turner could again be a candidate for elevation in Week 6 at Tampa Bay.