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Trent Williams OT | SF
49ers' Trent Williams: Suiting up Sunday
Williams (knee) is active for Sunday's matchup with the Saints, Briana Jeannel of the 49ers' official site reports.
The starting left tackle was listed as a non-participant in practice Wednesday and Thursday before logging a limited session Friday, though his absences were described as rest days and not injury related. Williams has started every game he's played in since joining the 49ers in 2020.
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Jameis Winston QB | NYG
Giants' Jameis Winston: Again serving as emergency QB
Winston (coach's decision) is inactive for Sunday's game against the Cowboys but is serving as the Giants emergency quarterback.
First-round rookie Jaxson Dart will again work as the backup to starter Russell Wilson, with Winston continuing to suit up as the emergency No. 3 quarterback. Wilson struggled in his Giants debut last week, and Dart could get an opportunity if those struggles continue Sunday. Winston, however, can only take the field in Dallas if both Wilson and Dart are injured.
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Raheim Sanders RB | CLE
Browns' Raheim Sanders: Sitting out in Week 2
Sanders (coach's decision) is inactive for Sunday's game against the Ravens.
Sanders suited up as the Browns' No. 3 running back in the team's 17-16 loss to the Bengals in the season opener and was able to make an impact in his limited snaps, finishing with three yards and a touchdown on three carries. However, with rookie second-round pick Quinshon Judkins (not injury related) having been reinstated from the commissioner's exempt list and added back to the 53-man roster after turning in full practices Thursday and Friday, Sanders will slide to fourth on the depth chart at running back and won't dress Sunday. Unless the Browns lose Judkins, Jerome Ford or Dylan Sampson to an injury in a given week, inactive statuses could start to become the norm for Sanders, an undrafted rookie out of South Carolina.
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Trey Palmer WR | NO
Saints' Trey Palmer: Healthy scratch Week 2
Palmer (coach's decision) is inactive for Sunday's game against the 49ers.
Palmer was claimed off waivers by the Saints in late August after failing to make the Buccaneers' 53-man roster at the end of training camp. However, the 2023 sixth-rounder has been a healthy scratch in each of the first two games of the regular season, and he's unlikely to see the field unless Chris Olave, Rashid Shaheed, Brandin Cooks, Devaughn Vele or Mason Tipton were to miss time. Palmer's next opportunity to suit up is Week 3 against the Seahawks on Sunday, Sept. 21.
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Jordan Watkins WR | SF
49ers' Jordan Watkins: Pro debut pushed back
Watkins (coach's decision) is inactive for Sunday's game at New Orleans, Briana Jeannel of the 49ers' official site reports.
Watkins didn't suit up Week 1 due to a lingering high-ankle sprain, but after capping Week 2 prep with a full practice Friday, the rookie fourth-round pick was cleared ahead of Sunday's contest. However, he'll be a healthy scratch while Jauan Jennings (shoulder), Ricky Pearsall, Kendrick Bourne, Marquez Valdes-Scantling and Skyy Moore handle WR snaps. Watkins' next chance to make his pro debut is Sunday, Sept. 21 against the Cardinals.
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Quinn Ewers QB | JAC
Dolphins' Quinn Ewers: Emergency QB for Week 2
Ewers (coach's decision) is inactive and will serve as the Dolphins' emergency third-string quarterback for Sunday's game against the Patriots.
Ewers will be Miami's emergency QB3 for a second consecutive week. That means he would only see the field Sunday if both Tua Tagovailoa and Zach Wilson were to leave the game due to injury, illness or ejection.
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Kalel Mullings RB | TEN
Titans' Kalel Mullings: Inactive Sunday
Mullings (ankle) is inactive for Sunday's game against the Rams, Jim Wyatt of the Titans' official site reports.
The running back injured his ankle on a punt return during Tennessee's season-opening loss to the Broncos and proceeded to miss practice in the week leading up to this contest. With Tony Pollard and Julius Chestnut leading the Titans' backfield, Jordan Mims, who was elevated Saturday from the practice squad, will step in as the third option.
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Jaydon Blue RB | PHI
Cowboys' Jaydon Blue: Inactive for second straight game
Blue (coach's decision) is inactive for Sunday's game against the Giants.
The rookie fifth-round draft pick will have to wait at least one more week to make his NFL debut, as Dallas will proceed with Javonte Williams and Miles Sanders as its lone active running backs for the second straight game. Though Williams looks to be locked in as Dallas' lead back after producing two touchdowns and 64 total yards on 17 touches in the Week 1 loss to the Eagles, Blue could eventually unseat Sanders -- who committed a costly fumble in the opener -- for the No. 2 role as the season unfolds.
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Jaire Alexander CB | PHI
Ravens' Jaire Alexander: Healthy scratch Week 2
Alexander (coach's decision) is inactive for Sunday's game against the Browns.
Alexander was able to practice in full Thursday and Friday after being limited in Wednesday's session due to a lingering knee issue that caused him to miss time during training camp in August. He played just 33 of 85 defensive snaps during the Ravens' Week 1 loss to the Bills, so an extra week of rest could be what Alexander needs to be fully healthy, and his next chance to play is Week 3 against the Lions on Monday, Sept. 22. Chidobe Awuzie will likely step in as the Ravens' second starting outside corner opposite Nate Wiggins in Alexander's absence.
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Curtis Samuel WR | BUF
Bills' Curtis Samuel: Inactive again
Samuel (coach's decision) is inactive for Sunday's game against the Jets.
Samuel was also a healthy scratch in Week 1, so it may take an injury to a fellow WR to get him back on Buffalo's game-day roster. Khalil Shakir, Keon Coleman, Joshua Palmer, Elijah Moore and Tyrell Shavers are the Bills' available wide receivers versus the Jets.