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Drew Lock QB | SEA
Seahawks' Drew Lock: Tosses three touchdowns in win
Lock completed 19 of 26 passes for 235 yards with three touchdowns and no interceptions in Sunday's 31-7 victory over Arizona.
Lock didn't make it too hard on himself, looking for superstar wide receiver Jaxon Smith-Njigba early and often. The duo connected for an 82-yard score in the first quarter before later adding touchdowns of seven and 12 yards in the second half. Lock has tossed four touchdowns over the first two weeks, all of which have been to Smith-Njigba. The quarterback has completed 35 of 48 passes for 422 yards with four scores so far this season, and he could be asked to start another contest Week 3 versus the Commanders while Sam Darnold (hip) continues to recover.
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Denzel Boston WR | CLE
Browns' Denzel Boston: Scores another long TD in upset win
Boston caught five of seven targets for 95 yards and a touchdown in the Browns' 23-19 win over Tampa Bay on Sunday.
Boston's big play was a 55-yard touchdown late in the third quarter to pull the Browns even with the Bucs at 16-16. The rookie wideout caught a deep crosser and spun off several would-be tackles and dashed to the end zone. It was Boston's second long touchdown in as many weeks to begin his pro career. Through two games, the second-round pick has seven catches for 154 yards and two scores on 11 targets. He's shaping up as a boom-or-bust fantasy WR4 headed into next Sunday's home date with the Panthers.
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Jake Ferguson TE | DAL
Cowboys' Jake Ferguson: Bounces back with two TDs in win
Ferguson caught all four of his targets for 43 yards and two touchdowns in the Cowboys' 37-20 win over the Commanders on Sunday.
After a quiet Week 1 against the Giants in which he caught just two passes for six scoreless yards, Ferguson bounced back with a pair of red-zone touchdowns against Washington. His four targets were still just fourth on the team, tied with Javonte Williams and behind CeeDee Lamb (nine), George Pickens (eight) and Ryan Flournoy (six) on a day Dak Prescott attempted 31 passes. Ferguson is shaping up as a touchdown-or-bust fantasy tight end headed into Week 3 versus Baltimore.
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Jacoby Brissett QB | BAL
Cardinals' Jacoby Brissett: Ineffective against Seattle
Brissett completed 17 of 28 passes for 95 yards with a touchdown and an interception while also adding a seven-yard rush in Sunday's 31-7 loss to Seattle.
Brissett struggled to push the ball down the field against the Seahawks' vaunted secondary, and as a result, he was limited to just 5.4 yards per completion. The quarterback was able to connect with tight end Trey McBride for a two-yard score to open the second quarter, but that was the only bright spot on the day for the 33-year-old. He attempted to find wide receiver Michael Wilson deep down the left sideline in the third quarter, but Julian Love jumped in front of it for his the safety's second interception of the year. Brissett has proven to be more than capable of producing positive results for fantasy managers in his time with the Cardinals, and his next chance to get back on track will come Week 3 against the 49ers on the road.
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Marvin Harrison Jr. WR | HOU
Cardinals' Marvin Harrison: Blanked in Week 2
Harrison failed to catch his only target in Sunday's 31-7 loss to the Seahawks.
Harrison was held without a reception for the second time in three regular-season contests dating back to Week 17 of the 2025 campaign. The wide receiver has now gone four straight regular-season games without recording multiple receptions, and quarterback Jacoby Brissett clearly prefers other options like tight end Trey McBride and fellow wideout Michael Wilson over Harrison again in 2026. It's hard to be confident in the 24-year-old former first-round pick heading into the team's Week 3 matchup with San Francisco.
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De'Von Achane RB | MIA
Dolphins' De'Von Achane: Inefficient start against stacked fronts
Achane rushed 20 times for 74 yards while catching three of six targets for 19 yards in Sunday's 35-13 loss to the 49ers.
Achane racked up 23 touches after touching the ball 11 times in Week 1, but the speedster has struggled to find running room while consistently facing stacked boxes. He is averaging a meager 3.5 yards per rushing attempt heading into a Week 3 home game against the Chiefs, which is a departure from Achane's excellent efficiency in previous seasons, as he averaged 5.7 yards per carry last season and has a career mark of 5.6 YPC. Defenses are daring Malik Willis and Miami's underwhelming wide-receiver room to beat them, and Miami's offense hasn't been up to the task during the team's 0-2 start.
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Ladd McConkey WR | LAC
Chargers' Ladd McConkey: Three grabs in Week 2 loss
McConkey (ribs) secured all three targets for 35 yards in the Chargers' 26-14 loss to the Raiders on Sunday.
McConkey gained clearance from his questionable tag due to a rib injury to suit up, and the third-year wideout tied for the team lead in receptions while finishing second in receiving yards. However, it was a lackluster and mistake-filled day overall for the Chargers passing attack, so McConkey's numbers should also be viewed in that context. McConkey should play a critical role as Los Angeles looks to avoid what would be an alarming third straight loss to open the season in a Week 3 road showdown against the Bills next Sunday.
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Michael Wilson WR | ARI
Cardinals' Michael Wilson: Two catches in loss
Wilson caught two of seven targets for 18 yards in Sunday's 31-7 loss to the Seahawks.
Wilson and the rest of the Cardinals' offense never got going Sunday, but he still finished second on the team in targets behind tight end Trey McBride (10) in the contest. Wilson continues to be quarterback Jacoby Brissett's favorite option at wide receiver, garnering 14 targets over the first two games of the regular season. The 26-year-old will look to find paydirt for the first time in 2026 when Arizona travels to face the 49ers in Week 3.
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Christian McCaffrey RB | SF
49ers' Christian McCaffrey: Scores twice to reach 100 career TDs
McCaffrey rushed 10 times for 23 yards and two touchdowns while catching both of his targets for 43 yards in Sunday's 35-13 win over the Dolphins.
McCaffrey opened the scoring with a one-yard touchdown run in the first quarter and added another one-yard touchdown run in the third quarter. The two-touchdown performance brought McCaffrey's career regular-season touchdown total up to 100. Exactly half of those touchdowns have come with the 49ers, as McCaffrey joins Marshall Faulk and Randy Moss as the only players to score at least 50 touchdowns apiece for multiple teams, per ESPN Insights. McCaffrey should continue to contribute as both a runner and a pass catcher in Week 3 against the Cardinals.
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Ashton Jeanty RB | LV
Raiders' Ashton Jeanty: Handles 25 touches in Week 2 upset
Jeanty rushed 21 times for 48 yards and brought in four of seven targets for 15 yards in the Raiders' 26-14 win over the Chargers on Sunday.
Jeanty was the unquestioned leader of the Raiders' ground attack once again, and although he had to scratch and claw for every yard, the second-year back helped keep the Bolts' defense honest. Jeanty also finished second in receptions and tied for the team lead in targets, underscoring how central he is to what Las Vegas does on offense. Jeanty and his teammates will be gunning for a third consecutive victory to open the season when they tangle with the equally surprising Saints on the road next Sunday.