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Sauce Gardner CB | IND
Colts' Sauce Gardner: Achilles appears intact
Gardner is believed to have suffered a calf strain during Sunday's contest against the Texans, Tom Pelissero of NFL Network reports.
Gardner's Achilles appears to be intact, a fortunate report after the cornerback needed assistance returning to the locker room. Mekhi Blackmon will likely finish Sunday's game as the primary outside cornerback with Gardner being ruled out, but the starting corner may not be absent as long as initially feared.
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Jalen Milroe QB | SEA
Seahawks' Jalen Milroe: Serving as emergency QB
Milroe (coach's decision) is inactive for Sunday's matchup with the Vikings.
The quarterback has been playing this role for much of the season as he remains behind Sam Darnold and Drew Lock on the depth chart. Milroe has only played on three offensive snaps as a rookie.
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Christian Darrisaw OT | MIN
Vikings' Christian Darrisaw: Inactive for Week 13
Darrisaw (foot) is inactive for Sunday's game against the Seahawks.
Darrisaw will miss his third game of the season due to injury. The left tackle was only able to log a single limited practice this week on Friday, and it appears that was not sufficient for him to be able to suit up Sunday. Justin Skule will likely get the start at left tackle in Darrisaw's absence.
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Kyren Williams RB | LAR
Rams' Kyren Williams: Hurts ankle in Week 13
Williams exited Sunday's game at Carolina due to a right ankle injury, Adam Grosbard of The Orange County Register reports.
The Rams' medical staff examined Williams' right leg after his five-yard carry late in the first half before escorting him to the locker room. After halftime, the team deemed him questionable to return. Blake Corum is on hand to pace Los Angeles' backfield for as long as Williams is off the field.
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Adam Thielen WR | PIT
Vikings' Adam Thielen: Healthy scratch Week 13
Thielen (coach's decision) is inactive for Sunday's game against the Seahawks.
The veteran wide receiver's role in the offense has noticeably dipped since the Vikings' Week 6 bye, and Thielen will be an observer for Sunday's road game in Seattle. His absence means Tai Felton and Myles Price will be the rotational wideouts for the Vikings behind Justin Jefferson, Jordan Addison and Jalen Nailor. Thielen's next opportunity to play is Week 14 against the Commanders on Sunday, Dec. 7, though he's unlikely to play in that game unless there is an injury to the Vikings' wide receiver corps.
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Jack Conklin OT | CLE
Browns' Jack Conklin: Enters concussion protocol
Conklin (concussion) has been ruled out for the rest of Sunday's game against the 49ers, Chris Easterling of the Akron Beacon Journal reports.
Conklin was evaluated by medical staff in the first half, and with the confirmation of a concussion, the veteran offensive lineman will not return to Sunday's game. KT Leveston will remain at right tackle the rest of the way.
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Israel Abanikanda RB | DAL
Israel Abanikanda: Signs with Dallas
The Cowboys signed Abanikanda to the practice squad Sunday.
Abanikanda was cut from the Packers' practice squad Sept. 8 and was a free agent throughout the 2025 season before Sunday's signing. The signing likely is due to Phil Mafah (shoulder) and Miles Sanders (knee) being on injured reserve, and fifth-round rookie Jaydon Blue's (coach's decision) consistent role as a healthy scratch.
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Kyren Williams RB | LAR
Rams' Kyren Williams: Departs Sunday's game
Williams went to the locker room Sunday at Carolina with an apparent leg injury, Adam Grosbard of The Orange County Register reports.
Williams removed himself from the game with 2:34 remaining in the first half following a five-yard run, after which trainers were examining his right leg. The exact nature of the issue isn't known, but he had seven carries for 39 yards and didn't haul in either of his two targets before his exit. Blake Corum will take over the Rams backfield for as long as Williams is sidelined.