NBA picks: Cade Cunningham included in Thunder vs. Pistons same-game parlay for Wednesday, Feb. 25
The two best teams in the NBA meet Wednesday when the Thunder visit the Pistons, and we've built a three-leg same-game parlay for the contest

The Detroit Pistons are sitting at the top of the Eastern Conference as one of the breakout teams of the 2025-26 NBA season, but they struggled in Monday's loss against the San Antonio Spurs, one of the West's best teams. The Pistons have another big test in front of them on Wednesday, Feb. 25 when they host the defending champion Oklahoma City Thunder. The Thunder have won three in a row, most recently taking down the Raptors 116-107 on Tuesday.
Shai Gilgeous-Alexander and Jalen Williams remain out for the Thunder. SGA has been out since early February, while Williams returned from an extended absence for a few games before aggravating a hamstring issue. He's been out for the last four contests. Oklahoma City is also going to be without Ajay Mitchell and Isaiah Hartenstein, while Chet Holmgren and Alex Caruso are being listed as doubtful on the second night of a back-to-back. On Detroit's side, Isaiah Stewart continues to serve his suspension.
We've built a three-leg same-game parlay for this potential NBA Finals preview with odds from DraftKings Sportsbook and recommendations from the SportsLine Projection Model. It simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered Week 19 on a sizzling 38-18 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.
Thunder vs. Pistons same-game parlay picks
- Thunder +10.5
- Cade Cunningham Over 24.5 points
- Jalen Duren Over 11.5 rebounds
Thunder +10.5
Oklahoma City has managed to stay afloat despite the absences of SGA and Williams, thanks to a deep roster with contributors at every level. Cason Wallace and Isaiah Joe have exploded over the last few games, and both are good to go tonight. Oklahoma City is 15-13 ATS on the road but Detroit is just 11-13 ATS as a home favorite this season. The SportsLine model has the Thunder covering in 51% of simulations despite the long injury report.
Cade Cunningham Over 24.5 points
After going for 42 points against the Knicks, Detroit's MVP candidate has cooled down substantially. Cunningham logged 18 points against the Bulls and 16 points against the Spurs, struggling mightily from the field in the latter contest. Even though Oklahoma City's defense is No. 1 in defensive rating and opponent field goal percentage, the Thunder are essentially punting on this game with most of their top rotation players sitting out. Cunningham is projected for 24.6 points in the SportsLine props model.
Jalen Duren Over 11.5 rebounds
The Thunder do have a weakness, and it's on the glass. They rank 23rd in opponent rebounds, and Duren should feast in this matchup after logging 27 rebounds over the last two games. The SportsLine props model has him at 13.4 rebounds on Wednesday and he'll benefit with Hartenstein and Holmgren both missing this contest.
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