Manager Aaron Boone said after Wednesday's 4-1 loss to Minnesota that Goldschmidt was unavailable off the bench due to a right knee injury, Max Goodman of NJ.com reports.

The Yankees are still in the process of evaluating Goldschmidt's injury, but the Yankees believe that the veteran first baseman is dealing with a low-grade sprain, per Brendan Kuty of The Athletic. Boone suggested that a stint on the injured list could be in the offing for Goldschmidt, which would likely result in Ben Rice settling in as New York's everyday first baseman and Austin Wells regaining the primary catcher role.

Mountcastle went 2-for-3 with a solo home run and a walk in Wednesday's 4-3 win over the Mariners.

Mountcastle tied the game with a 394-foot leadoff blast in the seventh inning and recorded his first multi-hit effort since returning from the injured list Friday. Since being reinstated, he's gone 4-for-17 with two homers and a 2:5 BB:K while starting in five consecutive games. On the season, the 28-year-old is slashing .245/.283/.368 with four homers, 17 RBI, 21 runs scored, and one stolen base across 219 plate appearances.

Busch went 1-for-3 with a solo home run and two total RBI in Wednesday's 4-1 win over the Blue Jays.

Busch got the scoring started with a home run against Toronto starter Kevin Gausman in the top of the third inning, his 23rd of the season, then chipped in a sac fly later in the game. The first baseman continues to mash against right-handed pitching with a .924 OPS and all but two of his long balls in those matchups. Busch's 23 home runs and 67 RBI are also both already career highs.

Pasquantino went 2-for-5 with a double, a home run and four RBI in Wednesday's 8-7 loss to the Nationals.

The first baseman did his best to get the Royals back into the game after they fell behind 5-0 in the top of the first inning, driving in Kansas City's first run with a groundout in the bottom of the first and then adding a three-run shot off Jake Irvin in the fourth. Pasquantino has three homers and 11 RBI in the last four games, and over 19 contests since his last day off July 22, he's batting .240 (18-for-75) with seven of his 22 long balls on the season, plus 23 of his 80 RBI.

Lowe went 1-for-3 with two walks and a grand slam in Wednesday's 8-7 win over the Royals.

He got the fireworks started by hooking a Seth Lugo curveball over the fence in the right-field corner in the first inning. It was Lowe's first homer since July 19, ending a 20-game power drought, and his 16th of the season. The veteran first baseman still has some work to do to put his slump behind him, however -- in 23 contests since the All-Star break, he's batting only .160 (12-for-75) with three doubles, two long balls and seven RBI.

Kurtz is not in the Athletics' starting lineup against the Rays on Wednesday.

Kurtz will begin Wednesday's game on the bench after starting in the Athletics' last 14 games, with Tyler Soderstrom shifting over to first base and batting in the cleanup spot. Over that 14-game span, Kurtz has gone 13-for-50 (.260) with 10 runs, two doubles and three RBI.

Toro is absent from the lineup for Wednesday's contest in Houston.

After starting at first base in each of the first two games of the series, Toro will begin Wednesday's festivities on the bench. Romy Gonzalez is handling first base and batting sixth for the Red Sox.

Rodriguez (elbow) underwent ulnar nerve transposition surgery Tuesday, Alex Stumpf of MLB.com reports.

Rodriguez is currently on the 60-day injured list and will not return this season, as he faces a multi-month rehab. Rodriguez last saw the field in early June but was injured while throwing a ball to second base in warmups between innings. He played in 18 games for the Pirates this season, slashing .173/.246/.250 with four doubles, two RBI, five runs scored and a 5:14 BB:K across 57 plate appearances.

Goldschmidt is not in the lineup for Wednesday's game versus the Twins.

Goldschmidt had started both of the first two games of the series, but his playing time versus right-handers has been trending down in the second half. The Yankees will turn to Ben Rice at first base and Austin Wells at catcher in the series finale against Minnesota.

Santana is absent from the lineup for Wednesday's contest versus the Marlins.

It's the third time in the last four games Santana has been out of the lineup and the sixth time across the last 10 tilts versus right-handed pitching that the 39-year-old has sat out. C.J. Kayfus is handling first base for the Guardians on Wednesday.