Smith (1-0) retired both batters he faced to earn the extra-inning win over the Astros on Wednesday.

Smith got the last two outs of the ninth inning, and Emmanuel Clase closed out the game in the 10th after the Guardians grabbed the lead. Aside from giving up two runs in back-to-back outings in mid-April, Smith has been one of the Guardians' many successful relievers early in the year after winning a job in the bullpen out of spring training. He's pitched to a 2.45 ERA, 1.09 WHIP and 22:6 K:BB over his first 14.2 major-league innings, and he's added two holds.

The Twins optioned Boushley to Triple-A St. Paul on Thursday, Betsy Helfand of the St. Paul Pioneer Press reports.

Minnesota will wait until shortly before Friday's series opener versus the Red Sox to announce a corresponding roster move, but Boushley will head back to Triple-A just one day after being called up. He didn't appear in long relief Wednesday in the Twins' 10-5 win over the White Sox.

The Orioles designated Ramirez for assignment Thursday, Matt Weyrich of The Baltimore Sun reports.

Ramirez is the roster casualty as the Orioles bring back Kyle Bradish (elbow) from the 15-day injured list to start Thursday's contest versus the Yankees. The 28-year-old reliever holds an 8.74 ERA over eight relief appearances this season between the Mets and Orioles.

Clase earned the save over the Astros on Wednesday, striking out one over a perfect 10th inning.

Clase entered the contest with a one-run lead in the bottom of the 10th and needed only five pitches to retire the side and secure his ninth save of the season. The right-hander has now converted each of his last five save attempts (over nine appearances), posting a 10:1 K:BB over that stretch. He now sports a pristine 0.55 ERA following Wednesday's scoreless appearance.

Holmes earned the save Wednesday, allowing one hit with three strikeouts over 1.2 scoreless innings against Baltimore.

Holmes capped off an excellent game by the Yankees pitching staff, as they yielded three hits and no runs as a whole. Individually, Holmes logged three strikeouts for the first time all year and his 1.2 innings of work marked his longest outing of the campaign. He's yet to allow an earned run during 15 innings and is tied for the MLB lead in saves with 10.

Wentz worked around a hit and a walk to pitch a scoreless inning of relief and earn a hold in Wednesday's 4-1 win over the Cardinals. He struck out one.

Wentz has pitched well all season in relief, and he now has his first hold to show for it. The lefty has a miniscule 0.79 ERA across 11.1 innings and he's struck out 14. The move to the bullpen has done wonders for Wentz, as he struggled mightily as a starter last year, posting a 6.80 ERA and 1.68 WHIP across 105.2 innings. He figures to stick in a relief role moving forward.

Rodriguez cleared waivers Wednesday and was sent outright to Triple-A Worcester, Chris Cotillo of The Springfield Republican reports.

Rodriguez was designated for assignment Sunday after posting a 6.55 ERA and 1.55 WHIP across 11 innings with the Red Sox. The 32-year-old southpaw will now officially remain with the organization, but he will not have the benefit of a 40-man roster spot and will likely need to show significant improvement in the minors before getting another shot in Boston.

Yankees manager Aaron Boone said Wednesday that Burdi (hip) could head out on a minor-league rehab assignment soon, Gary Phillips of the New York Daily News reports.

Placed on the 15-day injured list April 19 with right hip inflammation, Burdi doesn't look as though he'll be in store for an especially lengthy stint on the shelf. Burdi struck out eight over 6.1 scoreless innings out of the bullpen prior to being placed on the IL.

Orioles manager Brandon Hyde said he's not sure whether Kimbrel (back) will be available to pitch Wednesday versus the Yankees, Danielle Allentuck of TheBaltimoreBanner.com reports.

Hyde said something similar prior to Tuesday's game and Kimbrel did not appear in that contest. It's possible the skipper is just practicing some gamesmanship here so that the Yankees have less information to work with, but either way it doesn't sound like there will be clarification prior to Wednesday's game. If Kimbrel is indeed unavailable again, Yennier Cano and Danny Coulombe are candidates for saves.

Lange earned the save in Wednesday's 4-1 win over the Cardinals, recording two strikeouts and a walk over 1.1 scoreless innings.

Lange struck out Willson Contreras for the final out in the eighth inning before closing the door in the ninth, working around a two-out walk to Paul Goldschmidt for his second save this season. Jason Foley was likely unavailable Wednesday after pitching three of the last four days, though Lange has continued to pitch well in a set-up role -- he's held opponents scoreless in his last 7.2 innings, allowing just two hits and two walks while striking out nine in that span. The 28-year-old right-hander lowered his ERA to 0.75 with a 1.17 WHIP 16:9 K:BB across 12 innings this season.