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Yandy Diaz DH | TB
Rays' Yandy Diaz: Keeps up hot hitting in win
Diaz 3-for-4 with an RBI and a run scored in Wednesday's 6-1 win over the Reds.
It was Diaz's third three-hit attack of the campaign and his eighth multi-hit effort. There had been some initial concern that the first baseman's production might take a hit in 2026 with the Rays moving back to pitcher-friendly Tropicana Field, but Diaz has quelled those fears to this point. Through 108 plate appearances, he's slashing a potent .340/.426/.489 with seven extra-base hits, 18 RBI, 13 runs scored and one stolen base.
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Tanner Bibee SP | CLE
Guardians' Tanner Bibee: Saddled with tough loss Wednesday
Bibee (0-3) took the loss Wednesday, allowing two runs on five hits and two walks over six innings as the Guardians were downed 2-0 by the Astros. He struck out three.
A two-run home run by Yordan Alvarez on Bibee's ninth pitch of the game proved to be the only offense either team would produce, but the right-hander shook it off and stuck around long enough to record his second straight quality start on 95 pitches (59 strikes). Bibee's ratios are still inflated by an eight-run disaster in Atlanta on April 12, but he's given up three runs or fewer in five of his six starts to begin the season, posting a 4.45 ERA, 1.45 WHIP and 26:11 K:BB through 30.1 innings. He'll look for his first win of 2026 in his next trip to the mound, which is set to come at home early next week against the Rays.
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Miguel Andujar DH | SD
Padres' Miguel Andujar: Not in Wednesday's lineup
Andujar is not in the Padres' starting lineup against the Rockies on Wednesday.
Andujar has been productive at the plate to open the season, with the 31-year-old slashing .308/.345/.423 with one steal and two RBI over 55 plate appearances. He'll be on the bench for the start of Wednesday's contest, with Gavin Sheets serving as the designated hitter and Nick Castellanos filling in at first base.
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Yordan Alvarez DH | HOU
Astros' Yordan Alvarez: Stays hot with 11th homer
Alvarez went 3-for-4 with a two-run home run in Wednesday's 2-0 win over the Guardians.
Alvarez took Tanner Bibee deep in the first inning after a Carlos Correa double to lead off the game, and that proved to be the only offense either pitching staff would allow on the afternoon. Alvarez has quickly erased the stink of a disappointing, injury-marred 2025 season, and through his first 26 games in the current campaign, he leads the majors with 11 homers and 26 RBI to go along with a sizzling .347/.466/.779 slash line.
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Freddy Fermin C | SD
Padres' Freddy Fermin: Sitting Wednesday
Fermin is not in the Padres' starting lineup against the Rockies on Wednesday.
With Fermin opening Wednesday's game on the bench, Luis Campusano will serve behind home plate and bat eighth while catching pitches from Walker Buehler. Fermin has struggled at the plate this season, slashing .194/.333/.278 with two RBI and nine runs scored over 45 plate appearances.
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Enyel De Los Santos RP | HOU
Astros' Enyel De Los Santos: Pockets third save
De Los Santos gave up a hit and a walk over 1.1 scoreless innings Wednesday to record his third save of the season in a 2-0 win over the Guardians. He struck out one.
The journeyman righty wrapped up the combined shutout on 24 pitches (16 strikes), although De Los Santos did make things interesting by putting the tying runner on base in the ninth inning with two outs. He's converted three straight save chances since April 14, emerging as the preferred closing option for manager Joe Espada while the Astros continue to navigate the absence of Josh Hader (bicep), but De Los Santos' 3.86 ERA, 1.18 WHIP and 8:3 K:BB through 9.1 innings this season don't suggest he'll have a long-term spot in the team's high-leverage crew.
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Amed Rosario 3B | NYY
Yankees' Amed Rosario: Drawing sixth straight start
Rosario will start at third base and bat fifth in Wednesday's game against the Red Sox.
Though he'll remain in the lineup for a sixth straight game while Ryan McMahon takes a seat, Rosario has largely been the beneficiary of the Yankees facing five left-handed starters during that stretch. The 30-year-old has been productive in his part-time role this season, slashing .250/.302/.500 with three home runs, nine RBI and five runs over 53 plate appearances.
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Ryan McMahon 3B | NYY
Yankees' Ryan McMahon: Out against lefty again
McMahon is out of the lineup for Wednesday's game against the Red Sox.
McMahon is on the bench for the fifth time in six games while the Yankees navigate a stretch that's been heavy on matchups with left-handed starting pitchers. Amed Rosario will get the nod at third base in McMahon's stead Wednesday while southpaw Ranger Suarez takes the hill for Boston.
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Peter Lambert SP | HOU
Astros' Peter Lambert: Fans eight in impressive outing
Lambert (1-1) picked up the win in Wednesday's 2-0 victory over the Guardians, allowing three hits and three walks over six scoreless innings. He struck out eight.
The 29-year-old right-hander fanned eight batters for a second straight start since being called up to plug a hole in the Astros' injury-ravaged rotation. Lambert racked up 32 called or swinging strikes among his 96 pitches (61 total strikes) Wednesday, and the former Rockie seems to be enjoying pitching at sea level on a consistent basis. After producing a 1.84 ERA and 0.99 WHIP in 14.2 innings for Triple-A Sugar Land to begin the season, Lambert's given Houston a 3.27 ERA, 1.27 WHIP and 16:4 K:BB over his first 11 big-league frames. He lines up to make his next start on the road early next week in Baltimore.