Fantasy Football Week 4 Start 'Em & Sit 'Em Quarterbacks: Dak Prescott dominates the slate, plus sleepers

Prescott just had his best game of the season in Week 3 against Baltimore with 33.9 Fantasy points, and hopefully that's a sign of things to come. He should stay hot in Week 4 at the Giants, and he has a great history in this NFC East rivalry. In his past five games against the Giants, Prescott is averaging 265.4 passing yards with 11 total touchdowns and four interceptions. He threw for 404 yards, four touchdowns, one interception, and a rushing touchdown, the last time he played the Giants in 2023.

Mayfield suffered his first bad game of the season in Week 3 against Denver when he scored just 10.5 Fantasy points, but he should bounce back in Week 4 against the Eagles. Jordan Love and Kirk Cousins both had at least 241 passing yards and two touchdowns against Philadelphia, and Mayfield destroyed the Eagles in the playoffs last season with 337 passing yards, three touchdowns and no interceptions, along with 16 rushing yards.

Smith has faced the Lions in each of the past two seasons in Detroit, and he's combined for 648 passing yards, four touchdowns and no interceptions, along with 69 rushing yards and a touchdown, in those two outings. I'm expecting another solid performance against the Lions in Week 4, and this should be Smith's best game to date since he's yet to score more than 19.9 Fantasy points. I'm trusting Smith as a low-end starter in all leagues.

Darnold looks awesome right now in Kevin O'Connell's offense, and he's scored at least 23.9 Fantasy points in each of his past two games against the 49ers and Texans, with six passing touchdowns over that span. This week, he's taking on a Packers defense that has more interceptions (seven) than touchdowns allowed (five), but Green Bay is also ninth in passing yards allowed to quarterbacks with 742. I'm buying this hot start by Darnold, and he's worth using as a low-end starter in all leagues.

Purdy looks like he'll get some help this week with Deebo Samuel (calf) and George Kittle (hamstring) back at practice, but Purdy didn't need them in Week 3 at the Rams when he passed for 292 yards and three touchdowns, along with 41 rushing yards. Aaron Rodgers and Geno Smith combined for 608 passing yards and three touchdowns against the Patriots in the past two games, and Purdy should be considered a low-end starter this week. Hopefully, Brandon Aiyuk steps up with his first big game of the season, and we'll see what happens with Jauan Jennings now that everyone is healthy. But I expect Purdy to keep it rolling in this matchup with New England in Week 4.

Stafford pulled off a great comeback win in Week 3 against the 49ers, but he only scored 14.8 Fantasy points in the 27-24 victory. He's now scored 16.7 Fantasy points or less in three games this season, and it's tough to trust him in this matchup with the Bears when he's without Puka Nacua (knee) and Cooper Kupp (ankle). Chicago has yet to allow multiple touchdowns to any quarterback this year, including matchups with C.J. Stroud and Anthony Richardson over the past two games.

Lawrence continued his lackluster play in Week 3 at Buffalo with 11.4 Fantasy points, and he's now scored 13.3 Fantasy points or less in all three games this season. It will be tough to trust him in Week 4 at Houston even though the Texans just allowed four passing touchdowns against Sam Darnold in Week 3. In his last five games against Houston, Lawrence has passed for an average of 258.2 yards with three total touchdowns and five interceptions.

Rodgers played great against the Patriots in Week 3 with 25 Fantasy points, and he's now scored at least 19.1 Fantasy points in two games in a row. But Denver is actually a tough matchup, and the Broncos have yet to allow a quarterback to pass for 175 yards or multiple touchdown passes in a game this season against Geno Smith, Justin Fields and Baker Mayfield. I would only start Rodgers in Superflex and two-quarterback leagues in Week 4.

The Saints defense has been tough on opposing quarterbacks so far this season, and in the past two weeks, New Orleans has held Dak Prescott and Jalen Hurts to a combined one touchdown and three interceptions. Now, that duo passed for a combined 604 yards, but neither scored more than 15 Fantasy points. Cousins has topped 15 Fantasy points just once this year, and he's not worth trusting in this matchup in anything more than Superflex and two-quarterback leagues.

Richardson got off to a hot start in Week 1 against Houston with 30.1 Fantasy points, but the past two weeks against Green Bay and Chicago have been tough. He's combined for just 16.9 Fantasy points against the Packers and Bears, and he's struggled to throw the ball in those outings with a combined five interceptions. It won't get easier for him against the Steelers, who have allowed just two touchdowns with four interceptions against Kirk Cousins, Bo Nix and Justin Herbert. Hopefully, this is a game where Richardson gets his production on the ground, but he might not post a big stat line in this matchup. I would lower expectations for Richardson if you start him this week in one-quarterback leagues.