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Samaje Perine RB | CIN
Bengals' Samaje Perine: Efficient in Week 1 win
Perine rushed five times for 20 yards and caught all three targets for 30 yards in a 33-27 win over Tampa Bay on Sunday.
Perine was the only Bengals running back besides starter Chase Brown (16-56-1 rushing line) to record a carry, and the former also finished with Cincinnati's third-highest receiving yardage total. Perine fell off quite a bit as a pass catcher last year, finishing with just 17 receptions for 87 yards over 15 games, so his usage in that capacity Sunday was promising in terms of his potential fantasy value. The Bengals next make a trip to Houston, and though the Texans were one of the league's best defenses last year, they gave up 409 total yards to Buffalo on Sunday.
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Tyler Allgeier RB | ARI
Cardinals' Tyler Allgeier: Robust workload in Week 1 win
Allgeier rushed 17 times for 61 yards and brought in both targets for nine yards in the Cardinals' 26-14 win over the Chargers on Sunday.
Allgeier lived up to his No. 1 slotting on the Week 1 depth chart, outpacing Jeremiyah Love by six carries and matching the rookie's reception total, albeit on two fewer targets. Allgeier did scuffle for rushing yards all afternoon long, but the veteran back helped keep the Chargers defense honest and proved capable of leading the ground attack. Love should be in line for a progressive boost in volume as the season unfolds, and there's no doubt as to which player between him and Allgeier has the higher ceiling; nevertheless, the latter should continue to see plenty of opportunity during a Week 2 home divisional clash with the defending champion Seahawks next Sunday.
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Keaton Mitchell RB | LAC
Chargers' Keaton Mitchell: Unimpressive in Chargers debut
Mitchell rushed four times for nine yards in a Week 1 loss to Arizona on Sunday. He added 47 yards on two kickoff returns.
Mitchell had a long rush of eight yards but combined for just three yards on his other three carries. While he also contributed in the return game, it was a bland Chargers debut for the 24-year-old, who joined Los Angeles as a free agent in March. The Chargers' run game as a whole was largely stifled Sunday, as Omarion Hampton -- the only other RB on the team to log a carry -- finished with a mediocre 43 yards on 12 carries, though he did score a touchdown. Mitchell will look to make more of an impression in Week 2 versus Las Vegas next Sunday.
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Ray Davis RB | BUF
Bills' Ray Davis: Handles one touch in Week 1
Davis rushed one time for three yards in Buffalo's 36-31 win over the Texans on Sunday.
Frank Gore actually out-snapped Davis 10-5 behind James Cook, as both Davis and Gore rushed one time for three yards. If something were to ever happen to Cook, it looks like Gore could actually have a bigger role than expected, making Davis a shakier bench stash in fantasy.
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Mike Washington Jr. RB | LV
Raiders' Mike Washington: Impresses on seven carries in win
Washington rushed seven times for 41 yards in the Raiders' 27-13 win over the Dolphins on Sunday.
After Ashton Jeanty dealt with an ankle sprain for the previous month, it was unclear if the Raiders would dial things back with their star running back. Jeanty went on to handle a full workload, rushing 23 times for 102 yards, while also leading the team in catches and receiving yards with a 6-45-2 line. Washington looked good on his seven chances, but it's clear Jeanty is healthy, making Washington a mere bench stash in fantasy.
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Woody Marks RB | HOU
Texans' Woody Marks: Splits snaps 50-50 with Montgomery
Marks rushed nine times for 42 yards and caught his lone target for a two-yard loss in the Texans' 36-31 loss to the Bills on Sunday.
While David Montgomery stole the headlines with three total touchdowns, Montgomery wasn't exactly efficient with his 20 carries, turning them into just 60 yards (3.0 YPC). Marks averaged 4.7 yards per carry with his nine attempts and actually out-snapped his veteran backfield mate 40 to 39 and ran 20 routes to Montgomery's 14, proving the 50-50 split talk from the summer to be true in the season opener. Marks remains an elite fantasy bench stash with some standalone value as an RB3 during bye weeks.
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Brian Robinson Jr. RB | ATL
Falcons' Brian Robinson: Handles nine carries in Week 1
Robinson rushed nine times for 31 yards in the Falcons' 20-13 loss to the Steelers on Sunday.
As expected, Robinson spelled Bijan Robinson and was a non-factor in the passing game, as Bijan out-carried him 21 to nine and out-targeted Brian 10 to zero. Brian has no standalone fantasy value but is a preferred bench stash as the next man up in the Atlanta backfield.
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Jordan Mason RB | MIN
Vikings' Jordan Mason: Scores short TD in Week 1 win
Mason rushed 15 times for 59 yards and a touchdown but wasn't targeted in Sunday's 39-22 win over the Packers.
Mason had three more carries than Aaron Jones, and neither of Minnesota's top two running backs recorded a catch. Jones and Mason each had a short touchdown run as the Vikings compiled 22 unanswered fourth-quarter points, with Mason's coming on a one-yard run with 4:48 to play. Mason set a career high with six rushing touchdowns during the 2025 regular season while rushing for 758 yards in his first year with the Vikings following a three-year stint in San Francisco. Jones and Mason are expected to split carries again in Week 2 at Chicago.
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MarShawn Lloyd RB | GB
Packers' MarShawn Lloyd: Leading rusher in ineffective RB room
Lloyd rushed 13 times for 37 yards and didn't catch his lone target in Sunday's 39-22 loss to the Vikings.
Lloyd worked ahead of Chris Brooks (seven carries for 29 yards) in a Packers backfield that struggled to generate much in the absence of Josh Jacobs (personal), who is on the Commissioner's Exempt List. Jordan Love threw 42 passes compared to 20 combined carries for Lloyd and Brooks, even though Green Bay led for most of the game prior to being outscored 22-0 in the fourth quarter. Lloyd looks poised to handle double-digit touches again in Week 2 against the Jets.
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Ashton Jeanty RB | LV
Raiders' Ashton Jeanty: Two TDs in Week 1 win
Jeanty rushed 23 times for 102 yards and secured all six targets for 45 yards and two touchdowns in the Raiders' 27-13 win over the Dolphins on Sunday.
Jeanty shook off the ankle injury that had plagued him for weeks leading into Week 1 by handling a voluminous workload with impressive efficacy. He set the pace for the Raiders in both rushing and receiving yards on the afternoon, and he shared the team lead in receptions as well. The 2025 first-round pick's pair of receiving scores were each from 13 yards out and transpired in the second and third quarters. With his health apparently no longer in question and Las Vegas' offense looking crisp in its first game under head coach Klint Kubiak's scheme, Jeanty's prospects are bright heading into a Week 2 road matchup against the Chargers next Sunday.