Gray (knee) is active for Sunday's game against the Lions, Dan Salomone of the Giants' official site reports.

Gray was activated off the Giants' reserve/PUP list Saturday, and the third-year running back has been cleared to make his 2025 regular-season debut Sunday. He will serve as the team's RB3 behind Tyrone Tracy and Devin Singletary.

Vaki (ankle) is active for Sunday's game against the Giants.

Vaki will once again be the primary depth option behind Jahmyr Gibbs and David Montgomery at the running back position. The rookie has climbed the depth chart by being a strong kick return option as well as running back, and if Gibbs or Montgomery were to go down, Vaki would be next up for the Lions' offense.

Reynolds (coach's decision) is inactive for Sunday's game against the Giants.

Reynolds will be a healthy scratch for consecutive weeks, with the team seemingly continuing to try rookie running back Sione Vaki at third-string running back and as the second kick returner. The Lions will once again roll with Jahmyr Gibbs, David Montgomery, Sione Vaki and Jacob Saylors at running back for Sunday's game.

Herbert (coach's decision) is inactive for Sunday's game against the Ravens.

Herbert was unavailable the past two games due to a groin injury but will be inactive again Sunday despite being recovered from the injury. Kene Nwangwu will instead serve as the No. 3 tailback behind Breece Hall and Isaiah Davis.

Nwangwu (hamstring) is active for Sunday's game against Baltimore.

Nwangwu was limited in the last two practices of Week 12 prep due to a hamstring injury, but he has been given the green light to play Sunday after going through pregame warmups. Nwangwu will mostly contribute on special teams as a returner on kickoffs, but he will also will serve as the Jets' No. 3 RB behind Breece Hall and Isaiah Davis due to Khalil Herbert (coach's decision) being inactive.

Mullings (ankle) is active for Sunday's game against the Seahawks.

Mullings was activated off injured reserve Saturday in anticipation for Sunday's contest, his first game since Week 3 against the Colts. The rookie sixth-rounder has worked his way back from an ankle injury he sustained in that Week 3 loss and will take his place behind Tony Pollard and Tyjae Spears as the third running back for the Titans' offense.

Ali (coach's decision) is inactive for Sunday's matchup with the Jets.

The running back remains behind Derrick Henry, Justice Hill and Keaton Mitchell on the depth chart. Ali has recorded 535 yards on kickoff returns this year, though he appears to be behind Mitchell for that role at the moment.

Ouzts (elbow/personal) is active for Sunday's game against the Titans.

Outzts was a full participant in Friday's practice after missing the first two sessions of the week due to a personal matter and elbow injury. The rookie fifth-rounder has ultimately been cleared to play Sunday, and the converted fullback will continue to give the Seahawks a blocking presence out of the backfield.

Mitchell (coach's decision) is inactive for Sunday's matchup with the Colts, Matt McMullen of the Chiefs' official site reports.

The running back made his season debut last Sunday against the Broncos but only played on seven of 70 offensive snaps. Mitchell is a healthy scratch even with Isiah Pacheco still out due to a knee issue. Kareem Hunt and Brashard Smith got most of Kansas City's offensive snaps at the running back spot a week ago.

Wilson is slated to lead the Packers backfield Sunday versus the Vikings with Josh Jacobs (knee) inactive, Mike Spofford of the Packers' official site reports.

The decision on Jacobs came down to a pregame warmup, which he didn't pass. Wilson thus will be the top running back for Green Bay in Week 12. In the three contests in which he earned double-digit touches this season, he averaged 12.3 touches for 72.3 yards from scrimmage per game while scoring one rushing TD. Chris Brooks and practice-squad elevation Pierre Strong are on hand for the snaps that don't go to Wilson.