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Latavius Murray RB | BUF
Ravens' Latavius Murray: Doubtful for Thursday
Murray (ankle) is listed as doubtful for Thursday's game in Miami, Adam H. Beasley of Pro Football Network reports.
Murray didn't practice at all this week and now is all but certain to miss a third straight game. Devonta Freeman has been filling in as the starter, with Le'Veon Bell and Ty'Son Williams working in reserve. Murray's next chance to play will come 10 days later against the Bears on Nov. 21.
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Jamaal Williams RB | NO
Lions' Jamaal Williams: Misses practice after bye
Williams (thigh) didn't practice Wednesday, but did some running off to the side during the portion that was open to the media, Tim Twentyman of the Lions' official site reports.
After playing through chest and hip issues earlier in the year, Williams missed Week 8 with a thigh injury that's apparently still bothering him after on the heels of a Week 9 bye. If he can't play this Sunday in Pittsburgh, the Lions will turn to Jermar Jefferson and/or Godwin Igwebuike behind lead back D'Andre Swift.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Not at practice
Kamara wasn't spotted at practice Wednesday, Katherine Terrell of The Athletic reports.
The Saints will release their first official Week 10 injury report later Wednesday, at which time it will be known whether the star running back is banged up, getting rest or missing practice for another reason. Kamara and the Saints head on the road to face Tennessee this Sunday.
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D'Ernest Johnson RB | TEN
Browns' D'Ernest Johnson: Could get another start
Johnson will make another start in the event teammate Nick Chubb (illness) isn't reinstated from the reserve/COVID-19 list before Sunday's game in New England, Scott Petrak of the Elyria Chronicle-Telegram reports.
Johnson's previous start, Week 7 against Denver, yielded 22 carries for 146 yards and a touchdown and two catches for 22 yards on a 69-percent snap share, while backups Demetric Felton and John Kelly combined for just four carries and three targets. A full repeat of the Week 7 outing is a lot to ask in New England, but Johnson will have a busy afternoon if Chubb doesn't end up playing. In order to suit up, Chubb needs to return negative tests on back-to-back days, after initially testing positive for COVID-19 on Tuesday.
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Clyde Edwards-Helaire RB | KC
Chiefs' Clyde Edwards-Helaire: Returns to practice
The Chiefs designated Edwards-Helaire (knee) for return from injured reserve Wednesday, Adam Teicher of ESPN.com reports.
Edwards-Helaire will thus resume practicing Wednesday while opening a 21-day window for the Chiefs to either reinstate him to the active roster or place him on IR for the rest of the season. The target date for a game appearance presumably is this Sunday in Las Vegas or Week 11 against Dallas, considering the Chiefs have a bye on tap Week 12. Fill-in starter Darrel Williams has been functional for both the Chiefs and fantasy managers thanks to his pass catching and blocking, but he's averaging only 3.6 yards per carry for the season and 3.5 since taking on the starting role.
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Antonio Gibson RB | NE
Football Team's Antonio Gibson: Remains limited after bye
Gibson (shin) was a limited participant at Wednesday's practice, Nicki Jhabvala of The Washington Post reports.
Gibson played through a stress fracture in his shin in each of Washington's five games before a Week 9 bye, racking up 77 touches for 301 yards from scrimmage and three touchdowns. In the same time span, change-of-pace back J.D. McKissic totaled a 50-325-1 line, respectively. Gibson appears to be operating under similar practice limitations from before the midseason respite, so his status should continue to be watched to ensure he's out there on game days.
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Rhamondre Stevenson RB | NE
Patriots' Rhamondre Stevenson: Misses Wednesday's practice
Stevenson (concussion) didn't practice Wednesday, Zack Cox of NESN.com reports.
Nor did lead back Damien Harris, with both players still in the NFL's concussion protocol. According to Cox, Stevenson and Harris were spotted taking part in conditioning work on a separate field during Wednesday's session, but until they are cleared to practice, Brandon Bolden and J.J. Taylor are the team's only available options at running back.
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Damien Harris RB | BUF
Patriots' Damien Harris: Sidelined Wednesday
Harris (concussion) didn't practice Wednesday, Zack Cox of NESN.com reports.
Along with Harris, Rhamondre Stevenson was sidelined for the Patriots' first Week 10 practice, as both players remain in the NFL's concussion protocol. According to Cox, the two running backs were spotted taking part in conditioning work on a separate field Wednesday, but until one or both are cleared to practice, Brandon Bolden and J.J. Taylor are the Patriots' only available options at the position.
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Zack Moss RB | CIN
Bills' Zack Moss: Not practicing Wednesday
Moss remains in the NFL's concussion protocol and won't practice Wednesday, Alaina Getzenberg of ESPN.com reports.
The running back still has two more opportunities to gain clearance to practice in advance of Sunday's game against the Jets, but Moss's absence from on-field work to begin the week suggests he's not a lock to play this weekend. If Moss sits out, Devin Singletary would likely have a clear path to a lead role out of the Buffalo backfield.
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Demetric Felton RB | WAS
Browns' Demetric Felton: Week 10 status TBD
Coach Kevin Stefanski said Wednesday that he does not have any updates on the status of Felton (illness) for Week 10, Nate Ulrich of the Akron Beacon Journal reports.
Stefanski said the same of Nick Chubb (illness), as both he and Felton tested positive for COVID-19 on Tuesday. As a result, both running backs now reside on the reserve/COVID-19 list and will need to log two negative test results at least 24 hours apart before being cleared to return to action. Kareem Hunt (calf) has already been ruled out for Sunday's contest against the Patriots, so D'Ernest Johnson could once again be poised for a valuable role as the lead in Cleveland's backfield.