Kamara (ankle) is questionable for Sunday's game against New England, Ross Jackson of WWL Louisiana reports.

Early reports suggested Kamara hurt his ankle during Wednesday's practice, but he clarified Thursday that the injury initially occurred during a win over the Giants on Sunday. That may also explain why Kendre Miller took on so much of the rushing workload, especially late in the game. This week, Kamara was a limited practice participant Wednesday through Friday, with Mike Triplett of NewOrleans.Football suggesting that the veteran RB is on track to play. There is some risk that Kamara's workload looks more like Week 5 than Weeks 1-4, but he'll presumably still start if he's declared active ahead of the 1:00 p.m. ET kickoff.

Williams (concussion) won't play Sunday against the 49ers, Greg Auman of Fox Sports reports.

Williams was evaluated for a concussion and cleared to return during Tampa Bay's Week 5 win over the Seahawks, but he experienced concussion symptoms after Thursday's practice and was subsequently placed in concussion protocol. Despite the absence of Bucky Irving (foot/shoulder) against Seattle, Williams' contributions were limited to kickoff returns on special teams. Williams' next chance to play will come Oct. 20 against the Lions.

Goodson (groin) has been ruled out for Sunday's game against the Cardinals, Amanda Foster of the Colts' official site reports.

Goodson will miss a second consecutive game due to the groin injury he sustained in Week 4 against the Rams. DJ Giddens will continue to work as the primary backup to workhorse running back Jonathan Taylor.

Dowdle will start Sunday's game against the Cowboys, as David Newton of ESPN.com reports that Chuba Hubbard (calf) has been ruled out.

Dowdle was outstanding in Hubbard's absence against the Dolphins in Week 5, as the former rushed for a career-high 206 yards in a 27-24 Panthers win. Dowdle should continue to hold a near-monopoly on Carolina's backfield touches against his former team, the Cowboys, with Trevor Etienne and DeeJay Dallas on hand to provide depth.

Hubbard (calf) has been ruled out for Sunday's game against Dallas.

Hubbard missed every practice for a second straight week, leaving Rico Dowdle as the leader of Carolina's backfield after his 206-yard rushing performance in last Sunday's win over the Dolphins. Dowdle gets another favorable matchup this coming Sunday, facing his former team in a game that's tied for the second-highest over/under (49.5) of Week 6.

Nwangwu (hamstring) doesn't carry an injury designation into Sunday's game against the Broncos, Rich Cimini of ESPN.com reports.

Nwangwu upgraded to full practice participation Friday to avoid an injury designation for Sunday's game in London. He's set to reclaim primary kickoff return duties on special teams in what will be Nwangwu's first action since Week 1.

Hubbard (calf) wasn't taking part in individual drills during the early stages of practice Friday, Mike Kaye of The Charlotte Observer reports.

Hubbard didn't practice Wednesday or Thursday, and with the running back trending toward another DNP on Friday, David Newton of ESPN.com notes that it doesn't look promising with regard to Hubbard's status for Sunday's game against the Cowboys. If he ends up deemed out for the contest, the stage would be set for Rico Dowdle to work as Carolina's lead back versus his former team.

Demercado has been the second running back in Arizona's rotation in practice, and head coach Jonathan Gannon said Demercado won't face additional punishment for his costly fumble in this past Sunday's loss to the Titans, Theo Mackie of the Arizona Republic reports.

Demercado appears set to reprise his change-of-pace role behind Michael Carter against the Colts on Sunday, which resulted in only thee touches for Demercado against Tennessee, one of which should have been a 72-yard touchdown run but instead resulted in a fumble at the goal line. Arizona could lean more on its backfield of Carter, Demercado and Bam Knight if starting quarterback Kyler Murray (foot) isn't available.

Carter has consistently been the first running back in Arizona's rotation in practice, suggesting he'll maintain the lead role Sunday against the Colts, Theo Mackie of the Arizona Republic reports.

Carter turned 23 touches into 73 yards from scrimmage and a touchdown in the Cardinals' Week 5 loss to the Titans. Head coach Jonathan Gannon said Emari Demercado won't be punished for his costly Week 5 fumble, so Demercado likely will continue to mix in for passing situations, while Bam Knight is on hand as the third-string backfield option with James Conner (foot) and Trey Benson (knee) on injured reserve. Conner's out for the season, while Benson won't be back any earlier than Week 10 against the Seahawks.

Tracy rushed four times for six yards and wasn't targeted in Thursday's 34-17 win over the Eagles.

Tracy returned from a two-game absence due to a shoulder injury but ceded the vast majority of backfield opportunities to Cam Skattebo, who turned 21 touches into 110 yards from scrimmage and three touchdowns. Tracy was on the field for 21 offensive snaps compared to only four for Devin Singletary, but Skattebo led the backfield with 49 snaps in addition to getting the lion's share of rushing opportunities. With Skattebo finding success in a workhorse role, Tracy likely will be relegated to a change-of-pace role moving forward.