Carter rushed the ball 18 times for 51 yards and a touchdown in Sunday's 22-21 loss to the Titans. He added five receptions on five targets for 22 yards.

Carter was expected to step into an expanded role with both James Conner (foot) and Trey Benson (knee) sidelined, though it was unclear exactly how touches would be distributed. Carter resoundingly served as the lead back for Arizona, accounting for 23 total touches, while Emari Demercado and Bam Knight combined for nine. He wasn't particularly efficient with the touches, though he did manage to find the end zone on a one-yard plunge early in the first quarter. Carter's involvement as a receiver was also particularly notable, as Demercado was projected to take over duties as the primary pass catcher out of the backfield. Carter looks to have reliable volume heading into a Week 6 matchup against the Colts, though this situation could remain fluid.

Henderson carried the ball six times for 24 yards and caught two of three targets for three yards in Sunday's 23-20 win over Buffalo.

Henderson finished as New England's leading rusher as part of a three-player committee, but it was Rhamondre Stevenson who cashed in both of the team's short rushing scores Sunday. The latter also coughed up his third fumble of the season, which could cut into Stevenson's playing time even after making two trips to the end zone. That potential scenario could open up more touches for Henderson going forward, though so far he has seen his fantasy value thwarted by the three-way timeshare. Until he has an uptick in usage, the second-round rookie will be stuck as a deep-league option.

Stevenson took seven carries for 14 yards, two touchdowns and a lost fumble while adding two receptions for 13 yards in Sunday's 23-20 win over the Bills.

Stevenson led New England's three-headed backfield with his seven carries Sunday, rewarding fantasy managers with a pair of trips to the end zone. The bad news for the veteran rusher was that his ball security woes continued with his third lost fumble in as many games. Stevenson's case of fumblitis didn't cost his team a shot at victory like it did in Week 3 against the Steelers. That said, it wouldn't be surprising if the Patriots lean more heavily on TreVeyon Henderson and Antonio Gibson going forward if Stevenson is unable to correct his turnover issues.

Cook rushed the ball 15 times for 49 yards in Sunday's 23-20 loss to the Patriots. He did not catch his only target.

Cook endured his worst game of the season both as a rusher and receiver. His longest rush of the day went for only nine yards, and he also went without a catch for the first time on the campaign. Positively, Cook still dominated opportunity out of Bills' backfield, with Ray Davis and Ty Johnson combining to see only four rushing attempts with zero targets. Cook should have a strong chance of bouncing back in Week 6 against Atlanta.

Miller accrued 10 rushes for 41 yards and hauled in his only target for eight yards during Sunday's 26-14 victory against the Giants.

Miller logged double-digit carries for the second week in a row. While he wasn't as productive as the Week 4 loss to Buffalo, the third-year running back paced the Saints in rushing attempts for the first time this season. He finished with two more carries than RB1 Alvin Kamara, who has had a very slow start to the season. Kamara's slump has opened more and more opportunities for Miller, including a season-high 39 percent of offensive snaps Sunday. If Kamara continues to struggle, then Miller could be in line for even more carries during the Week 6 matchup versus New England on Sunday, Oct. 12.

Rodriguez took five carries for seven yards and was not targeted as a receiver in Sunday's 27-10 win over the Chargers.

Jacory Croskey-Merritt (14-111-2) stole the show on offense in Sunday's victory, leaving nothing but scraps for the rest of Washington's backfield committee. Rodriguez still finished second in running back touches ahead of Jeremy McNichols (1-6-0), but neither backup made a fantasy impact behind Croskey-Merritt's huge performance. With his teammate breaking out in impressive fashion, Rodriguez should remain waiver-wire fodder in Week 6 against the Bears.

Charbonnet rushed nine times for 36 yards and a touchdown while catching one of two targets for 12 yards in Sunday's 38-35 loss to Tampa Bay.

Charbonnet finished with one less carry than Kenneth Walker (10-86-0) in the loss, but it was the former who punched in Seattle's only rushing score of the contest. The 24-year-old Charbonnet received seven fewer carries than the starter in his return from a foot injury in Week 4, but Sunday's near-even split in touches indicates a potential timeshare moving forward. If that trend holds true, then Charbonnet would see a slight bump in value at Walker's expense heading into next Sunday's tilt against the Jaguars.

Montgomery rushed the ball 18 times for 65 yards and a touchdown in Sunday's 37-24 win over the Bengals. He added one reception on one target for six yards while also completing one pass for three yards and a score.

Montgomery made his initial impact in the game as a passer, taking a direct snap and delivering a three-yard touchdown pass to Brock Wright early in the second quarter. He got going as a rusher in the second half, racking up 12 carries for 62 yards -- highlighted by an eight-yard touchdown run midway through the third quarter. While it wasn't his most efficient performance, Montgomery bounced back from a poor Week 4 showing while logging a season-high 18 carries.

Harvey rushed four times for 12 yards and brought in all three targets for 18 yards in the Broncos' 21-17 win over the Eagles on Sunday. He also returned four kickoffs for 83 yards.

Harvey remained the clear No. 2 RB behind J.K. Dobbins, who logged 20 carries. Harvey did continue enjoying a bigger role in the passing game than his veteran teammate, but he was at his most productive in his returner role. As long as Dobbins remains healthy and productive, Harvey projects to remain in the same complementary role that's afforded him 8.6 touches per contest heading into a Week 6 matchup against the Jets in London next Sunday.

Walker took 10 carries for 86 yards while catching one pass for no gain in Sunday's 38-35 loss to Tampa Bay.

Walker led Seattle in both carries and rushing production in Week 5, but it was backfield mate Zach Charbonnet (9-36-1) who cashed in the team's only rushing score in the loss. The touch distribution was far closer this time around compared to last week's seven-carry difference in the latter's return from injury, confirming the timeshare that exists when both runners are at full strength. Both players are worthy of flex spots in Week 6, even in a timeshare, with Walker being the preferred option for his early-down usage.