McCaffrey took 23 carries for 140 yards and a touchdown while corralling four of six targets for 41 yards in Sunday's 42-38 win over the Bears.

McCaffrey shouldered a heavier load on offense with star TE George Kittle (ankle) missing in action Sunday, resulting in a season-high 140 rushing yards from CMC. The 29-year-old's scamper to the end zone in the second quarter brought him up to an even 10 rushing scores on the year. McCaffrey has reached double-digit rushing touchdowns three times in his storied career, accomplishing the feat twice as a member of the 49ers. The versatile tailback's modest receiving totals on SNF puts a potential 1,000-1,000 season in jeopardy, as he would need 110 receiving yards in Week 18 in order to accomplish the incredible feat for the second time in his career. Fantasy managers should expect a heavy dose of the fantasy stud against the Seahawks with the NFC's No. 1 seed and a first-round bye on the line in the regular-season finale.

Sampson rushed the ball 11 times for 27 yards in Sunday's 13-6 win over the Steelers. He added three receptions on three targets for zero yards.

Sampson was able to return from a two-game absence, and he immediately led Cleveland's backfield with 14 touches. That translated to limited production, as he was inefficient as both a rusher and receiver. However, Sampson will likely retain a significant role for a more favorable Week 18 matchup against the Bengals.

Sanders rushed the ball eight times for 21 yards in Sunday's 13-6 win over the Steelers. He added one reception on two targets for 10 yards.

Sanders worked closely behind Dylan Sampson in the Cleveland backfield, logging nine touches to Sampson's 14. Sanders was unable to get much going on the ground, with his longest rush going for only six yards. He should maintain a split in the Browns' backfield heading into a Week 18 matchup against the Bengals, though his fantasy appeal remains minimal.

Singletary rushed the ball eight times for 45 yards and a touchdown in Sunday's 34-10 win over the Raiders. He added four receptions on four targets for 25 yards.

Tyrone Tracy slightly outpaced Singletary in touches, but Singletary had the more favorable fantasy role. He got the Giants' offense moving early, ripping off a 29-yard run before punching in a one-yard score one player later on the team's second possession. Singletary was also more involved as a pass catcher, logging a season-high four receptions while also topping 80 yards from scrimmage for the second time in his last four games. He should have the chance to end the season in strong form in a favorable Week 18 matchup against the Cowboys while working in a split out of the backfield with Tracy.

Tracy rushed the ball 14 times for 62 yards in Sunday's 34-10 win over the Raiders. He added one reception on two targets for minus-5 yards.

Tracy led the Giants' backfield in rushing attempts and was fairly efficient with his opportunity. Two of his carries went for at least 10 yards, the longer of which was a 23-yard scamper that pushed the team into field-goal range on their first possession of the second half. However, Tracy missed out on opportunities to Devin Singletary, both as a receiver and near the goal line, to limit his fantasy appeal. Nevertheless, Tracy has at least 60 yards on the ground in six of his last seven games heading into an exploitable Week 18 matchup against the Cowboys.

Hull tallied two carries for three yards during Sunday's 34-26 victory versus Tennessee.

Hull had a minimal workload for the fifth week in a row, while fellow backup running back Audric Estime saw an increased workload with a team-high 14 carries for 94 yards. These two have filled in for the Saints' depleted backfield with Devin Neal (hamstring) and Kendre Miller (knee) on IR while RB1 Alvin Kamara (knee) is still sidelined. The 25-year-old Hull has now totaled 17 carries for 36 yards across five appearances this season. He should once again see sparse usage in New Orleans' regular-season finale versus Atlanta.

Jeanty rushed the ball 16 times for 60 yards in Sunday's 34-10 loss to the Giants. He added two receptions on two targets for 13 yards.

Jeanty couldn't duplicate his Week 16 heroics and was extremely inefficient for most of the game. He delivered long runs of 24 and 14 yards in the second half to bolster his stat line, the former of which came with four minutes remaining in the game and the Raiders down three scores. Jeanty enters a Week 18 matchup against the Chiefs needing 112 rushing yards to reach 1,000 for his rookie season, though he's hit that mark only twice in 16 games to this point.

Barkley rushed 19 times for 68 yards and was not targeted as a receiver in Sunday's 13-12 win over Buffalo.

Barkley failed to break away from the Bills' athletic linebacking corps and was held to 3.6 yards per tote Sunday. The 28-year-old failed to extend his modest scoring streak to four games, culminating in a mediocre fantasy performance by the superstar's standards. It was also the first time this season that Barkley did not receive a target, but the workhorse still commanded 19 of Philadelphia's 23 backfield carries. Barkley and his 280-1,140-7 rushing line will attempt to finish off a solid, yet underwhelming, regular season against the Commanders in Week 18.

Johnson rushed five times for 15 yards and caught three of four targets for 33 yards in Sunday's 13-12 loss to the Eagles.

Johnson was able to tote the rock a season-high five times while corralling multiple passes for the eighth time in nine games. The running back has proven to be a reliable pass catcher for Buffalo, but unless he reaches the end zone, he doesn't have much fantasy utility in shallow leagues.

Tucker rushed two times for eight yards in Tampa Bay's loss to Miami on Sunday.

Tucker failed to reel in his lone target in the passing game. Tucker has been handling goal-line duties for the Bucs. Part of a three-way committee in the backfield, Tucker carries extremely minimal fantasy value ahead of a Week 18 date with the Panthers. He's a touchdown-or-bust proposition with Bucky Irving healthy.