Brown (illness) did not practice Wednesday.

Brown will have two more opportunities to retake the practice field before Cincinnati is forced to decide whether to assign him an official injury designation for Week 18. The starting running back is coming off his most productive game of the season, having carried the ball 22 times for 101 yards and two touchdowns while adding three catches for 40 yards during the Bengals' win over the Cardinals in Week 17. If able to suit up Week 18, Brown will get a chance to close out the 2025 campaign strong with a home matchup against Cleveland.

Dowdle (toe) practiced fully Wednesday, Darin Gantt of the Panthers' official site reports.

Dowdle was held out of Tuesday's walkthrough due to what coach Dave Canales called a sore toe, per Gannt. However, Dowdle's return to all activity one day later indicates the absence likely was maintenance-based more than anything. Since the Panthers' Week 14 bye, Dowdle has turned 45 touches into 160 yards from scrimmage and one TD, while fellow RB Chuba Hubbard notched 90 total yards and no TDs on 23 touches during that span. Expect a similar breakdown of reps between the two Saturday at Tampa Bay with a potential playoff berth on the line.

Cowboys head coach Brian Schottenheimer said Davis (eye) will be limited in practice Wednesday, Joe Hoyt of The Dallas Morning News reports.

Davis and starting running back Javonte Williams (shoulder) will both be listed as limited on Dallas' first injury report of Week 18, potentially paving the way for rookie Jaydon Blue to get involved on offense during Sunday's regular-season finale against the Giants. With Williams having been forced out early versus Washington on Christmas Day in Week 17, Davis went off for 103 rushing yards on 20 carries while failing to secure either of his two targets. Davis will stand to handle a significant workload versus New York in the event that he is cleared to play Sunday but Williams is not.

Coach Brian Schottenheimer said Williams (shoulder) will be listed as limited on Wednesday's practice report, Joe Hoyt of The Dallas Morning News reports.

The same can be said for No. 2 RB Malik Davis (eye), meaning rookie Jaydon Blue is the only healthy backfield option on the active roster at the moment. Williams himself didn't return to last Thursday's win at Washington after his four-yard TD run in the second quarter, finishing Week 17 with 13 carries for 54 yards and the score. The state of the Cowboys' ground game thus is in flux ahead of Sunday's regular-season finale at the Giants.

Dowdle (toe) is participating in practice Wednesday, Mike Kaye of The Charlotte Observer reports.

Dowdle missed Tuesday's walk-through practice due to a sore toe, so it's encouraging to see him already back on the field as at least a limited participant. As long as Dowdle is able to continue practicing in some capacity Thursday, it will bode well for his chances of being cleared to face the Buccaneers on Sunday, a contest that may determine the winner of the NFC South title. Dowdle exploded onto the scene midway through the 2025 regular season and revitalized Carolina's rushing game, but he's since been in a slump, having averaged just 47.3 rushing yards per game across his last seven appearances.

Hall (knee) won't practice Wednesday.

The same applies to Isaiah Davis (concussion), which leaves Kene Nwangwu and Khalil Herbert as the Jets' healthiest running backs as Sunday's season finale against the Bills approaches. Hall was forced out of the team's Week 17 loss the Patriots with a knee injury, an issue he downplayed later, per Rich Cimini of ESPN.com. However, with Hall set to log a DNP on Wednesday, his status will now need to be monitored ahead of Week 18 action.

Davis (concussion) will not practice Wednesday, Zack Rosenblatt of The Athletic reports.

Davis remains in the concussion protocol after being injured in Sunday's loss to the Patriots. Kene Nwangwu and Khalil Herbert would be options to handle backup duties behind Breece Hall against the Bills if Davis is unable to play.

Chestnut played all 20 of his snaps on special teams in Sunday's 34-26 loss to the Saints.

Chestnut has been active for all 16 of the Titans' games to date but has remained an afterthought on offense when Tennessee has had both Tony Pollard and Tyjae Spears available out of the backfield. For the season, Chestnut has logged just 11 carries (for 40 yards) and has drawn just two catchless targets.

Mullings gained four yards on his lone carry in Sunday's 34-26 loss to the Saints.

Mullings took the field for the just one of the Titans' 74 snaps on offense in the loss, carrying the ball on the final play of the game as Tennessee wound out the clock. Since being activated from injured reserve in late November, the rookie sixth-round pick out of Michigan has suited up in six straight games but has logged just three carries for seven yards. He's seen most of his playing time on special teams while Tony Pollard and Tyjae Spears have worked ahead of him at running back.

San Francisco general manager John Lynch said Wednesday that McCaffrey (back) is trending in the right direction to play Saturday against the Seahawks, Cam Inman of The San Jose Mercury News reports.

McCaffrey could not practice Tuesday due to back stiffness, leaving him two more opportunities to retake the practice field in advance of Saturday night's showdown against Seattle, the winner of which will clinch the NFC West title and the No. 1 playoff seed in the NFC. The 49ers may in part simply be taking a cautious approach to McCaffrey's health due to both his importance as the focal engine of the team's offense and the fact that he's handled 20-plus touches in five consecutive games. McCaffrey previously played through this back injury early December, but he hadn't been listed on San Francisco's injury reports in Week 16 and Week 17.