The Lions elevated Jefferson from the practice squad to the active roster ahead of Monday night's game against the 49ers.

Jefferson will be elevated for a second straight week and serve as the Lions' fourth-string running back behind Jahmyr Gibbs, Craig Reynolds and Sione Vaki. Jefferson played 12 snaps (five on offense, seven on special teams) during the Lions' Week 16 win over the Bears and logged three carries for 13 yards while hauling in his lone target for 10 yards.

Sanders (ankle), who remains on IR, will practice this week and could play in Sunday's Week 18 season finale against Atlanta, David Newton of ESPN.com reports.

Panthers head coach Dave Canales indicated Monday that Sanders was cleared to return to the field last week and said the veteran running back will practice this week. While Canales didn't state that Sanders will play Sunday against the Falcons, the head coach also didn't rule hm out. Sanders hasn't logged game action since hurting his ankle Week 10 against the Giants and landing on IR a few weeks later. If Sanders does suit up Sunday, he'd be added to a Carolina running-back room that recently lost Chuba Hubbard (calf/knee) and currently consists of Raheem Blackshear, Mike Boone and Velus Jones.

Hubbard (calf/knee), who is on IR, won't need any surgery in the offseason, David Newton of ESPN.com reports.

Hubbard put together a career-best season for the Panthers, rushing for 1,195 yards and 10 touchdowns on 250 carries while adding 171 yards and one touchdown on 43 receptions. However, the 25-year-old will finish the campaign on IR after suffering a Grade 2 calf strain late in the season. Since Hubbard won't need surgery on either the calf or the knee, he's likely to be ready to play by the start of the 2025 campaign. He's expected to be Carolina's top running back next season after signing a four-year contract extension this November.

Kamara (groin) wants to play Sunday versus Tampa Bay, but that decision will be left up to the Saints' medical staff, Katherine Terrell of ESPN.com reports.

Kamara has sat out each of New Orleans' past two games due to an adductor injury. The star running back didn't practice at all last week, and he'd almost certainly have to return in at least a limited capacity this week in order to have any chance of suiting up Sunday. Kendre Miller currently is in the concussion protocol, so Clyde Edwards-Helaire, Jamaal Williams and Jordan Mims could form the Saints backfield Week 18 if neither Kamara nor Miller is able to play.

Pollard (ankle/illness) might play Sunday against Houston, Jim Wyatt of the Titans' official site reports.

Pollard missed Sunday's loss to Jacksonville due to both an ankle injury and the flu. Tyjae Spears took over as the Titans' starting RB for the contest, but he suffered a concussion in the third quarter and is uncertain to be able to suit up Week 18. Though Tennessee has long been eliminated from playoff contention, Pollard could return to action for the season finale. However, if both Pollard and Spears don't suit up, the Titans backfield could be led by Julius Chestnut and Joshua Kelley.

Chiefs head coach Andy Reid said Monday that Pacheco (ribs) will "be available playoff-wise" but will be held back in practice this week, Charles Goldman of AtoZSports.com reports.

Pacheco hurt his ribs in Wednesday's Christmas Day win over Pittsburgh, and it would be a major surprise if he suits up Week 18 versus Denver with Kansas City already having locked up the No. 1 playoff seed in the AFC. The positive news on Pacheco is that he appears to be in no danger of missing any time in the postseason, and he'll have an extra week to recover from what Reid described as "tender" ribs with the Chiefs penciled in for a first-round bye. Kansas City may opt to rest starters beyond Pacheco on Sunday against the Broncos, and it wouldn't be surprising if the team gives Kareem Hunt the day off as well, which would put Samaje Perine and Carson Steele in positions to lead the backfield in the regular-season finale.

Wright did not log a carry or target during Sunday's 20-3 win over the Browns.

Wright didn't go without an offensive snap versus Cleveland as he had in Week 16 against San Francisco, but he was uninvolved in Miami's gameplan. The rookie fourth-round pick looks set to close out the regular season as an afterthought behind all of De'Von Achane, Raheem Mostert and Jeff Wilson at home against the Jets in Week 18.

Wilson rushed three times for five yards during Sunday's 20-3 win over the Browns.

Wilson again worked as the third backfield option for Miami behind De'Von Achane and Raheem Mostert, but none of the Dolphins' running backs were able to get much going on the ground versus Cleveland. The veteran is likely to continue working ahead of Jaylen Wright during Week 18's regular-season finale against the Jets, though his role isn't one that carries notable fantasy value.

Mostert rushed six times for three yards during Sunday's 20-3 win over Cleveland. He also secured both of his targets for 16 yards.

Mostert, De'Von Achane and Jeff Wilson were all inefficient out of the backfield versus the Browns, despite a game script in which Miami got out to an early lead and would have benefited from an ability to lean on the run. He'll attempt to bounce back Week 18 against the Jets, a divisional matchup in which a win could provide the Dolphins with a playoff berth.

Jones (quad) does not seem to be dealing with a major injury and has a realistic chance of playing Week 18 against Detroit, Ian Rapoport of NFL Network reports.

The Vikings pulled the running back from a Week 17 win out of caution after going up 27-10 near the end of the third quarter, although the decision nearly backfired when the Packers scored the next 15 points. It would stand to reason that Jones will suit up Sunday if he's at all able to, as the Vikings have a lot to play for. If they beat the Lions in the season finale, they'll secure the No. 1 seed in the NFC and get a first-round bye, while a loss would push them all the day down to the No. 5 seed.