NFL Player News

The Bills placed Samuel (elbow) on injured reserve Friday.

Samuel will now need to miss at least four games while on IR before being eligible to return to the active roster. The move was coupled with the signing of wide receiver Gabe Davis from the practice squad. The Tuesday signing of Brandin Cooks likely also plays a role in the team's decision to move Samuel to IR. The wide receiver participated in six regular-season games this season where he totaled seven receptions for 81 yards and one receiving touchdown.

Holani (hamstring) has been ruled out for Sunday's game against the Vikings, Bob Condotta of The Seattle Times reports.

Holani didn't practice this week and is a candidate for injured reserve after he was hurt against Tennessee last Sunday. Rashid Shaheed and Cody White will likely continue to handle kickoff-return duties for the Seahawks.

Ayomanor (hamstring) is questionable for Sunday's game against the Jaguars, Jim Wyatt of the Titans' official site reports.

The rookie wideout got in a trio of limited practices this week after missing last Sunday's loss to the Seahawks. Ayomanor has a 28-334-2 receiving line on 59 rookie-year targets through 10 contests. He's yet to reach 60 receiving yards in a single game and is only a fantasy option in the deepest of leagues.

Okonkwo (foot) is questionable for Sunday's game against the Jaguars, Jim Wyatt of the Titans' official site reports.

Okonkwo got in a limited practice Friday following Thursday's DNP, giving the tight end a chance to suit up against Jacksonville. If Okonkwo is unable to play, rookie Gunnar Helm would seem to be in line for more snaps on offense. Okonkwo has a scoreless 35-377-0 receiving line on 46 targets through 11 contests this season.

Demercado (ankle) has been ruled out for Sunday's game in Tampa Bay, Bo Brack of GoPHNX.com reports.

Demercado has yet to practice since sustaining a high-ankle sprain Week 11, but he was spotted working on the side with the rehab group at Friday's session, per Theo Mackie of The Arizona Republic. Demercado's next chance for game action is Sunday, Dec. 7 against the Rams, but at least for Week 13, Bam Knight (knee, questionable) and Michael Carter are the likely candidates for reps in the Cardinals backfield with Trey Benson (knee, IR) also ruled out.

Irving (shoulder/foot) is listed as questionable for Sunday's game against Arizona, with the expectation that he'll return to action after logging full practices all week, Jenna Laine of ESPN.com reports.

Irving won't necessarily return to his pre-injury role but should at least be back in the mix as a significant part of Tampa Bay's offense. His impressive fantasy production late last season and into this September makes him a viable lineup option in nearly any format despite workload uncertainty in the first game back from a two-month absence. Sean Tucker supplanted Rachaad White as the lead back during that time, potentially setting up a three-headed backfield now that Irving is expected to be active ahead of the 1:00 p.m. ET kickoff Sunday.

Knight (knee) is listed as questionable for Sunday's game at Tampa Bay, Bo Brack of GoPHNX.com reports.

With Trey Benson (knee) and Emari Demercado (ankle) ruled out for Week 13, Knight now is the only question mark among the Cardinals' running backs that are dealing with injuries. Knight's knee issue limited him in all three practices this week, and his status will be clarified about 90 minutes before Sunday's 1:00 p.m. ET kickoff. Assuming he's able to suit up this weekend, he and Michael Carter likely will split the backfield reps in some fashion, but Jermar Jefferson also may be on hand for his first touch of the season.

Mayfield (shoulder) is listed as questionable for Sunday's game against Arizona after upgrading to full practice participation Friday, Jenna Laine of ESPN.com reports.

The combination of a full practice and optimistic comments from coach Todd Bowles has Mayfield looking highly likely to play. Bowles told reporters that Mayfield "looked good" during Friday's practice and is "trending to play," per Rob Maaddi of the Associated Press. Mayfield's fantasy managers should nonetheless check back in before a 1:00 p.m. ET kickoff Sunday to make sure he's avoided late setbacks and is getting the nod.

Harrison (appendix) is listed as questionable for Sunday's game against the Buccaneers, Bo Brack of GoPHNX.com reports.

Harrison returned to practice Wednesday, two weeks after undergoing an appendectomy. He was a limited participant all week, including Friday, when he told reporters after practice that "some things feel uncomfortable" while others "feel kind of normal," per Tyler Drake of ArizonaSports.com. Cardinals head coach Jonathan Gannon told Brack that Harrison "moved around well" during practice, but Gannon didn't comment on expectations for the wideout's availability this Sunday for the 1:00 p.m. ET kickoff.

Waller (pectoral) is listed as questionable for Sunday's game against the Saints, Travis Wingfield of the Dolphins' official site reports.

Miami designated Waller for return from injured reserve Wednesday, after which he cobbled together three straight limited practices. Per David Furones of the South Florida Sun Sentinel, coach Mike McDaniel said Friday regarding Waller's chances to suit up this weekend that "if there's not a setback, I'm feeling optimistic." The Dolphins will need to activate Waller from IR by Saturday afternoon for him to have a chance to be active for Sunday's 1:00 p.m. ET kickoff.