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Patrick Surtain II CB | DEN
Broncos' Patrick Surtain: Won't play in Week 5
Surtain (ankle) has been ruled out for Sunday's game against the Chargers, Aric DiLalla of the Broncos' official site reports.
The news doesn't come as a surprise, as Surtain is expected to miss at least two games due to an ankle injury that he sustained against the 49ers in Week 4. The good news is that the injury isn't severe enough for him to go on injured reserve. However, Denver will be without its two starting outside cornerbacks in Surtain and Riley Moss (ribs) for Sunday's AFC West contest, leaving Jahdae Barron and Kris Abrams-Draine to be the starters. The Broncos' Week 6 tilt against the Seahawks is this upcoming Thursday, so Surtain figures to be held out of that game given the short turnaround.
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Darius Slayton WR | IND
Colts' Darius Slayton: Won't play against Pittsburgh
Slayton (knee) has been downgraded to out for Sunday's game against the Steelers.
Slayton drew the questionable tag for Sunday's game after logging a limited practice Friday due to a new knee issue. The veteran wide receiver -- who signed with the Colts on Sept. 21 -- will have to wait at least one more week to make his debut with his new team, with his next chance to do so being Week 6 against the Titans on Sunday, Oct. 18. Indianapolis could also be without veteran wideout Keenan Allen (groin), which would leave Josh Downs, Laquon Treadwell and Deion Burks as the top wide receivers for Sunday's road contest.
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Marvin Harrison Jr. WR | HOU
Cardinals' Marvin Harrison: Will sit amid trade talks
A trade for Harrison will not be completed "until after Sunday's games are played," but the Cardinals "feel comfortable enough" knowing it will occur that they will deactivate him for Sunday's game against the Lions, Adam Schefter of ESPN reports.
Harrison's long-term outlook is firmly up in the air after it was announced earlier Saturday that he will be traded to an unspecified team, but per the latest report, "The one certainty is that Harrison's time in Arizona is done." Michael Wilson and Trey McBride figure to remain plenty busy in the passing game, and Harrison's absence will open up some opportunities for Kendrick Bourne and presumably Jalen Brooks.
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Marvin Harrison Jr. WR | HOU
Cardinals' Marvin Harrison: Trade being finalized
The Cardinals are "finalizing a deal to trade Harrison" to an unspecified team, Adam Schefter of ESPN reports.
Harrison's destination is unclear, but he is on the move after spending two seasons and the early portion of the current campaign in Arizona. Per the report, the Cardinals informed Harrison "that he will be inactive for Sunday's game against the Lions as details of the trade are finalized," so one way or another he will not see action in Week 5.
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Noah Fant TE | NO
Saints' Noah Fant: Cleared to play vs. Minnesota
Fant (abdomen) does not carry an injury designation into Sunday's game against the Vikings.
Fant opened the week with back-to-back limited practices before logging a full session Friday, which was enough for him to shed an injury tag and return from a one-game absence due to an abdominal injury. He has an 8-66-3 receiving line (on 12 targets) through three regular-season games while operating as the Saints' TE2 behind Juwan Johnson.
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Tez Johnson WR | TB
Buccaneers' Tez Johnson: Hauls in 64-yard pass vs. Dallas
Johnson caught his lone target for 64 yards during Thursday's 24-16 win over the Cowboys.
Johnson took advantage of the Cowboys' lapse in the secondary, with the second-year wideout on the receiving end of a deep ball from Jalon Daniels that the former turned into a 64-yard catch that led to a one-yard touchdown run by Bucky Irving three plays later. It was Johnson's second catch of 40-plus yards this season and third since entering the league in 2025 as a seventh-round draft pick. It's hard to rely on consistent production from the Bucs' pass catchers while Daniels is under center instead of Baker Mayfield (thumb), though Johnson is capable of having occasional big plays.
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Sean Tucker RB | TB
Buccaneers' Sean Tucker: Fails to score goal-line TD
Tucker turned five carries into 18 yards during the Buccaneers' 24-16 win over the Cowboys on Thursday.
Four of Tucker's five carries came during the Buccaneers' offensive drive that spanned the late third quarter and into the fourth. He was given a goal-line rushing opportunity, but he was stuffed by the Cowboys' defense before crossing the plane on fourth-and-1, which prevented him from logging a rushing touchdown in back-to-back games. Tucker is firmly entrenched as the Bucs' RB3 but would stand to benefit from an increased snap count if one or both of Bucky Irving or Kenny Gainwell were to miss time. Fresh off their first win of the season, the Buccaneers will look to make it two victories in a row in Week 6 against the Steelers on Sunday, Oct. 18.
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Robert Beal Jr. DE | MIA
Dolphins' Robert Beal: Won't play in Week 5
Beal (hamstring) has been ruled out for Sunday's game against the Bengals.
Beal will miss a third consecutive game due to a hamstring injury he sustained in Week 2 against the 49ers. The Dolphins are on a bye for Week 6, so he'll have additional time to rest before Week 7 against the Jets on Sunday, Oct. 25.
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Kalia Davis DT | CLE
Browns' Kalia Davis: Ruled out for Sunday
Davis (quadriceps) has been ruled out ahead of Sunday's game against the Jets, Kelsey Russo of the Browns' official site reports.
The Browns opened Davis' 21-day practice window Tuesday. The defensive tackle practiced throughout Week 5 prep but is not quite ready to return to the active roster after missing the first four games of the 2026 regular season.
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Rashawn Slater OT | LAC
Chargers' Rashawn Slater: Moved to IR after surgery
The Chargers placed Slater (ankle) on injured reserve Friday.
Slater underwent ankle surgery Thursday after suffering a high-ankle sprain during Sunday's loss to the Seahawks. The left tackle will now need to miss at least four games on IR before the Chargers can return him to the active roster. With Slater out, Logan Taylor will be protecting Justin Herbert's blindside in the Chargers' Week 5 matchup against the Broncos.