Prysock suffered a shoulder injury and will not return to Thursday's preseason matchup with the Raiders, Noah Furtado of the San Francisco Chronicle reports.
The cornerback recorded one solo tackle before exiting. Prysock was selected by the 49ers in the fourth round of April's draft and is competing for a depth role on defense.
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49ers' Ephesians Prysock: Scooped by San Francisco
Rotowire
The 49ers selected Prysock in the fourth round of the 2026 NFL Draft, 139th overall.
In a lot of ways, Prysock is similar to former Washington teammate Tacario Davis, who was selected in the third round (72nd overall) by the Bengals. Prysock (6-foot-3, 196 pounds) is also an unusually tall corner, and he was only trivially slower than Davis in the 40 (4.41 versus Prysock's 4.45). Also like Davis, Prysock's tall frame dictates that he focus at the boundary corner position, and ideally in press man coverage or Cover-3 principles to best capitalize on his height, reach and speed. With guys this tall they usually struggle against quicker, smaller receivers or/and with zone transitions, though.