Manzardo went 3-for-4 with a two-run homer, a double, a triple and four total RBI in Thursday's 7-4 win over Kansas City.

Manzardo starred in Cleveland's Opening Day win, ultimately winding up a single shy of a cycle. The left-hander put the Guardians ahead 4-3 with a two-run homer off Angel Zerpa in the fourth inning before driving in two more runs with a triple in the 10th, the first of his MLB career. Manzardo already came into the season as a popular sleeper candidate after a strong showing in Spring Training. He slashed .234/.282/.421 with five homers and 15 RBI in 156 plate appearances as a rookie last year.

Smith isn't in the lineup for Thursday's game against the Cubs, Aaron Hughes of SI.com reports.

Smith is expected to receive the bulk of starts at DH while working in a platoon with Randal Grichuk. However, a matchup against lefty Justin Steele on Thursday will keep Smith in the dugout while Grichuk enters the lineup and bats seventh.

Tellez will start at first base and bat seventh in Thursday's opener against the Athletics, Daniel Kramer of MLB.com reports.

The 30-year-old had appeared in line to handled designated hitter duties, but he will play first base instead while Luke Raley occupies the DH spot. Tellez is looking for a bounce-back 2025 season after he slashed only .243/.299/.392 in 131 games last year for the Pirates.

The Brewers selected Bauers' contract from Triple-A Nashville on Thursday.

After producing a .199/.301/.361 slash line with 12 home runs and 13 stolen bases over 346 plate appearances for the Brewers in 2024, Bauers elected free agency following the season and re-signed with Milwaukee on a minor-league deal. He emerged from spring training with a roster spot after producing a .939 OPS in Cactus League play, but Bauers could struggle to see the extended playing time he received with the Brewers in 2024 unless injuries test Milwaukee's depth at first base and in the outfield. Bauers is on the bench for Thursday's season opener versus the Yankees.

Casas (hand) will start at first base and bat cleanup in Thursday's season opener in Texas.

Casas took a ball off his bare hand in the field earlier this week, but X-rays were negative, and he'll be good to go for the start of the season. The first baseman was limited to only 63 games in 2024 due to injury but heads into the 2025 campaign with a clean bill of health.

Walker (oblique) will start at first base and bat cleanup in Thursday's season opener versus the Mets, Matt Kawahara of the Houston Chronicle reports.

Walker didn't make any Grapefruit League appearances after March 2 due to left oblique soreness, but he resumed taking swings in batting practice nearly two weeks ago and was able to get in some competitive at-bats in minor-league games this past weekend. The first baseman also played the field in a simulated game Monday, clearing up most of the concern about his health heading into Opening Day. The Astros are counting on Walker providing some thump in the middle of the order after Houston traded away Kyle Tucker and let Alex Bregman walk in free agency this offseason.

The Pirates placed Horwitz (wrist) on the 10-day injured list Thursday, Kevin Gorman of TribLive.com reports.

Horwitz had right wrist surgery in early February and was given a 6-to-8-week estimated recovery timetable. According to MLB.com, Horwitz has began a throwing progression and is taking swings with the bat, but he's still a few weeks away from game action. Horwitz is expected to serve as the Pirates' primary first baseman once healthy.

Pasquantino (hamstring) will start at designated hitter and bat third in Thursday's season opener versus the Guardians.

Pasquantino suffered a Grade 1-plus right hamstring strain just five days ago, but he made enough improvement that the Royals are comfortable with him at least playing in a non-defensive role on Opening Day. Cavan Biggio will occupy Pasquantino's usual position at first base.

Casas (hand) is expected to be ready to play Thursday against the Rangers, Ian Browne of MLB.com reports.

X-rays were negative after Casas attempted to field a bad hop with his bare hand Monday. Manager Alex Cora noted after Tuesday's exhibition that Casas was sore but feeling "a lot better," while the decision to hold him out Tuesday was described as precautionary. With that, Casas appears to be in line to bat cleanup against right-hander Nathan Eovaldi on Opening Day, though fantasy managers may want to confirm his status before first pitch.

The Angels optioned Noda to Triple-A Salt Lake on Wednesday.

Noda batted .182 this spring, but 15 walks in 49 plate appearances helped him finish the Cactus League with an .813 OPS. Despite his display of plate discipline and ability to play first base and the corner outfield, he'll have to work his way back into the majors by maintaining success at the Triple-A level.