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Griffin Canning RP | SD
Padres' Griffin Canning: Reinstated for season debut
The Padres activated Canning (Achilles) from the 15-day injured list in advance of his scheduled start Sunday against the White Sox.
Canning is ready to make his 2026 MLB debut after completing a five-outing rehab assignment, which signaled the end of his journey back from Achilles surgery last June. The right-hander built up to five innings and 68 pitches during his final rehab appearance with Triple-A El Paso on Tuesday, so he'll likely have some workload limitations in his first outing with the Padres.
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Nick Lodolo SP | CIN
Reds' Nick Lodolo: Poised to come off IL on Friday
Lodolo (finger) is expected to return from the 15-day injured list to start Friday's home game against the Astros, Gordon Wittenmyer of The Cincinnati Enquirer reports.
Lodolo -- who has been on the shelf all season due to a blister on his left index finger -- made the third and final start of his rehab assignment Saturday, striking out six batters and allowing two earned runs on five hits and two walks over 4.1 innings for Triple-A Louisville. The left-hander built up to 79 pitches in the outing, so he should be ready to handle a fairly normal workload next weekend in what would be his 2026 debut for the Reds. Before the Reds lock Lodolo into their upcoming pitching schedule, he'll likely need to complete a bullpen session Monday or Tuesday without incident.
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Zack Littell RP | ARI
Nationals' Zack Littell: Pitching in bulk relief Sunday
Littell is expected to pitch in bulk relief behind opener PJ Poulin in Sunday's game against the Brewers, Mark Zuckerman of NatsJournal.com reports.
Poulin is expected pitch one or two innings before giving way to Littell, who will work behind an opener for the second time this season. The Nationals are hoping that the arrangement will yield better results from the veteran right-hander, who has an 8.37 ERA and 1.77 WHIP in 23.2 innings over his last five starts.
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Easton McGee RP | KC
Brewers' Easton McGee: Sent back to Triple-A
The Brewers optioned McGee to Triple-A Nashville on Sunday.
McGee will cede his spot on the 26-man active roster to right-hander Logan Henderson, who was recalled from Triple-A ahead of his start Sunday. After being called up from Triple-A on Friday, McGee tossed a scoreless inning out of the bullpen in his lone appearance with the big club.
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Logan Henderson SP | MIL
Brewers' Logan Henderson: Called up to start Sunday
The Brewers recalled Henderson from Triple-A Nashville to start Sunday's game against the Nationals, Todd Rosiak of the Milwaukee Journal Sentinel reports.
The right-hander was briefly up with the Brewers for a doubleheader in early April but has otherwise spent the first month-plus of the season at Triple-A. Henderson has been dominant for Nashville with a 1.02 ERA, 1.22 WHIP and 26:9 K:BB across 17.2 innings. The 24-year-old is now expected to get at least a couple turns through the rotation with Milwaukee after the placement of Brandon Woodruff (shoulder) on the injured list.
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Spencer Strider SP | ATL
Braves' Spencer Strider: Activated for 2026 MLB debut
Atlanta reinstated Strider (oblique) from the 15-day injured list to start Sunday's game at Colorado.
The right-hander has missed the first month-plus of the regular season while working his way back from an oblique strain, but he's ready to make his first big-league appearance of the year after a three-start rehab assignment. Strider built up to 82 pitches and five innings during his final rehab outing, so his workload shouldn't be significantly limited in his 2026 debut. In last year's return from internal brace surgery on his elbow, Strider had an up-and-down campaign with a 4.45 ERA, 1.40 WHIP and 131:51 K:BB across 125.1 innings.
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Trevor McDonald SP | SF
Giants' Trevor McDonald: Returned to Triple-A
The Giants optioned McDonald to Triple-A Sacramento on Friday.
McDonald had been up with the Giants to serve as their 27th man for Thursday's doubleheader with the Phillies. After going unused out of the bullpen in either contest, he was sent back to Sacramento, where he'll continue to work out of the rotation.
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Lucas Giolito SP | SD
Padres' Lucas Giolito: Completes second start at Single-A
Giolito struck out six and allowed three earned runs on five hits and one walk over 4.1 innings Thursday in his start for Single-A Lake Elsinore.
After remaining unsigned until reaching a one-year deal with the Padres on April 22, Giolito reported to Lake Elsinore shortly thereafter to essentially complete his own version of spring training. He's now made two starts for Lake Elsinore, and after covering 4.1 innings and tossing 70 pitches Thursday, Giolito looks to be close to fully stretched out. Giolito hasn't been especially sharp in either outing, however, so the Padres will likely have him make one or two more starts in the minors before he slots back into the big-league rotation. San Diego will have until May 16 to add him to its active roster.
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Nolan McLean SP | NYM
Mets' Nolan McLean: Early hook in no-decision
McLean did not factor into the decision in Saturday's 4-3 extra-inning loss to the Angels, allowing three runs on six hits and one walk with six strikeouts over four innings.
McLean didn't have his best stuff, inducing just six whiffs on a season-low 78 pitches and departing with a 3-1 deficit after allowing two runs in the fourth inning. It was a rare hiccup for the 24-year-old, though he's still yielded three earned runs or fewer in each of his seven outings this season. He owns a 2.97 ERA, 0.94 WHIP and 51:11 K:BB across 39.1 innings and lines up for a road matchup against the Diamondbacks next weekend.
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Ryan Feltner SP | COL
Rockies' Ryan Feltner: Nearing bullpen session
Feltner (elbow) has resumed throwing and is expected to schedule a bullpen session in the coming days, MLB.com reports.
Feltner landed on the injured list April 24 and appears to have avoided a serious injury. He is currently projected to return in mid-May, though he still has several steps remaining in his recovery.