Pena (finger) is not in the lineup for Thursday's opener against the Angels.

Per Chandler Rome of The Athletic, Pena has progressed enough in his recovery from a fractured right ring finger to avoid the 10-day injured list, but he's not quite ready to play in major-league games. Pena is at the Astros' nearby Triple-A Sugar Land affiliate Thursday morning getting in some live at-bats, and it's unclear whether he will be available off the bench Thursday or if Houston will play a man short. Consider him day-to-day for the time being. With Pena out, Carlos Correa will slide over to shortstop and Isaac Paredes will start at third base.

Hamilton is starting at third base and batting seventh Opening Day against the White Sox on Thursday.

The lefty-hitting Hamilton will end up getting the Opening Day nod at the hot corner over switch-hitting veteran Luis Rengifo, who inked a one-year $3.5 million deal with Milwaukee in February. Hamilton played in 91 regular-season games with Boston last year and finished the campaign with six homers, 22 steals and a .198/.257/.333 slash line in 177 plate appearances.

Mateo claimed a spot on Atlanta's Opening Day roster, Chad Bishop of The Atlanta Journal-Constitution reports.

The veteran utility player will provide some extra depth at shortstop behind Mauricio Dubon while Ha-Seong Kim (finger) is on the IL. Mateo has stolen double-digit bases in each of the last five seasons despite inconsistent playing time -- he went 15-for-17 on the basepaths in 2025 despite seeing just 83 plate appearances for the Orioles.

Jackson is out of the lineup for Thursday's game against the Twins.

Though Jackson beat out a number of competitors for the final position-player spot on the Orioles' Opening Day roster, he looks like he'll have to settle for a part-time role to begin the season, even while Jackson Holliday (hand) and Jordan Westburg (elbow) are on the injured list. Coby Mayo is expected to be Westburg's primary replacement at third base, while the Orioles could opt for a more of a timeshare between Jackson and Blaze Alexander at the keystone in Holliday's absence. The Orioles will turn to Alexander at second base for the opener.

The Nationals released Alcantara on Tuesday.

Alcantara was unable to win a utility job with the Nationals coming out of spring training, and rather than sticking around in the organization at Triple-A Rochester, he'll hit the open market in pursuit of an opportunity elsewhere. The 29-year-old switch-hitter saw action in one game at the big-league level with the Giants in 2025, going 0-for-4 with two strikeouts.

Shaw is starting in right field and batting ninth in Thursday's season opener against the Nationals.

Michael Conforto was expected to step in as the Cubs' primary right fielder versus right-handed pitching with Seiya Suzuki (knee) on the injured list, but Shaw will instead get the call Opening Day against Washington righty Cade Cavalli. Shaw almost exclusively played third base as rookie last season, but he prepared to fill a super-utility role during the offseason and will immediately get a look at one of his new positions Thursday. The 24-year-old struggled to a .689 OPS in 126 regular-season games last year in his first taste of the majors but is coming off a strong spring training, during which he batted .320/.417/.500 in 60 plate appearances.

Winn is starting at shortstop and batting cleanup in Thursday's opener versus the Rays.

Winn is an atypical cleanup hitter -- this will be just his fourth career start in the slot -- but the rebuilding Cardinals don't have many middle-of-the-order options. It's a boost for Winn's RBI outlook, as he should have chances to drive in runs with JJ Wetherholt, Ivan Herrera and Alec Burleson batting ahead of him.

Holliday (hand) is set to begin a rehab assignment Friday at Triple-A Norfolk.

Holliday didn't see any game action in spring training after undergoing surgery Feb. 12 to remove the fractured hook of the hamate bone in his right hand, but he resumed taking batting practice before the end of camp and was spotted taking part in fielding drills at Camden Yards on Wednesday, per Jake Rill of MLB.com. The 22-year-old evidently checked out fine following Wednesday's workout and is expected to be in the lineup when Norfolk opens its season Friday. Holliday will be eligible to return from the 10-day injured list next Wednesday, but because he missed all of spring training, the Orioles may want to keep him on assignment with Norfolk for a longer period prior to activating him. Until Holliday is deemed ready to rejoin the big club, the Orioles will likely turn to Blaze Alexander and Jeremiah Jackson to handle most of the reps at the keystone.

Lindor (hand) is starting at shortstop and batting leadoff in Thursday's opener against the Pirates.

Lindor is just six weeks removed from hamate bone surgery but is ready to roll for Opening Day after playing five Grapefruit League games. Power can sometimes be slow to come back after this type of procedure, but fantasy managers will nonetheless want to have Lindor locked and loaded into their lineups.

The Orioles reassigned Barrero to Triple-A Norfolk on Wednesday, Andy Kostka of TheBaltimoreBanner.com reports.

Barrero appeared in 22 games at the big-league level with St. Louis in 2025, but he finished last season in the Orioles organization as a member of the Norfolk roster and will return to the affiliate to begin the 2026 campaign. The 27-year-old came up short in his bid for a utility spot on the Orioles' Opening Day roster after slashing just .105/.150/.289 over 40 plate appearances during the Grapefruit League.