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Ryan Helsley RP | BAL
Orioles' Ryan Helsley: Grabs save in Orioles' debut
Helsley earned the save in Thursday's 2-1 victory over the Twins, allowing one hit while striking out three in a scoreless ninth inning.
It was a strong showing from Helsley, who was tasked with closing out a one-run victory in his Baltimore debut. The right-hander will be the Orioles' primary closer with Felix Bautista (shoulder) expected to miss the majority of the regular season. Helsley made 58 appearances (56 innings) between the Cardinals and Mets last year, posting a 4.50 ERA with a 1.54 WHIP and 63 strikeouts while converting 21 of 30 save chances.
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Bryan Ramos 3B | BAL
Orioles' Bryan Ramos: Staying with Baltimore
The Orioles assigned Ramos to Triple-A Norfolk on Thursday, Jacob Calvin Meyer of The Baltimore Sun reports.
After failing to make the Opening Day roster and with no minor-league options left, the Orioles opted to designate Ramos for assignment Tuesday. He cleared waivers Thursday and has opted to remain in the organization with Norfolk. Ramos spent most of the 2025 season in Triple-A, but he could see some major-league action in 2026 if Baltimore requires depth at third base.
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C.J. Kayfus LF | CLE
Guardians' CJ Kayfus: Not in Thursday's lineup
Kayfus isn't in the lineup for Thursday's game against the Mariners.
Kayfus was making starts in the outfield and at first base for the Guardians toward the end of last year, but he will stay put on the bench to begin Cleveland's season opener. Steven Kwan, Daniel Schneemann and Chase DeLauter will start across the outfield Thursday, and Rhys Hoskins will get the nod at first base against Seattle righty Logan Gilbert.
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Jose Berrios SP | TOR
Blue Jays' Jose Berrios: Will throw off mound this week
Blue Jays general manager Ross Atkins said Thursday that Berrios (elbow) will throw off the mound before the end of this week, Mitch Bannon of The Athletic reports.
Berrios was diagnosed last week with a stress fracture in his right elbow, but he and the Blue Jays believe that the hurler will be able to pitch through the injury. The right-hander hasn't made a game appearance in three weeks, so even if things go smoothly with his elbow, Berrios will need time to get built up before Toronto considers him for its rotation.
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Shane Bieber SP | TOR
Blue Jays' Shane Bieber: Mound work on tap
Blue Jays GM Ross Atkins said Thursday that Bieber (elbow) will throw off a mound this week, Keegan Matheson of MLB.com reports.
The right-hander has been limited to throwing on flat ground while working his way back from shoulder fatigue, so a return to mound work is a significant development in his rehab program. Bieber still has a lengthy road ahead of him while building up to face live batters and eventually embarking on a rehab assignment, but a return in early May still appears to be on the table.
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Trey Yesavage SP | TOR
Blue Jays' Trey Yesavage: Velocity up in minor-league game
Blue Jays general manager Ross Atkins said Thursday that Yesavage's (shoulder) velocity "bumped back up" during a "very effective" appearance in a minor-league game Wednesday, Mitch Bannon of The Athletic reports.
It's an encouraging step for Yesavage, who did not make any spring training appearances while battling a right shoulder impingement. A rehab assignment for the rookie right-hander would appear imminent, and he will likely require several rehab starts before he's ready to rejoin the Blue Jays' rotation.
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Chandler Simpson LF | TB
Rays' Chandler Simpson: Taking seat Opening Day
Simpson is out of the lineup for Thursday's season opener versus the Cardinals, Marc Topkin of the Tampa Bay Times reports.
Simpson closed out spring training with a six-game hitting streak and went 3-for-3 on steal attempts during that stretch, quelling most of the concerns about the left hamstring injury that had slowed him earlier in camp. He should be a fixture in the lineup against righties, but the Rays may be more selective in exposing the left-handed-hitting Simpson to same-handed pitching in 2026 after he produced a .299/.330/.299 slash line (79 wRC+) in 113 plate appearances versus lefties as a rookie. Simpson will cede left field to the right-handed-hitting Ryan Vilade while southpaw Matthew Liberatore takes the bump for St. Louis in the opener.
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Evan Carter CF | TEX
Rangers' Evan Carter: Opening in apparent platoon
Carter is not in the lineup for Thursday's season opener against the Phillies.
Manager Skip Schumaker indicated during spring training that Carter will get some chances against left-handed pitching early in the season, but the outfielder will hit the bench Thursday with southpaw Cristopher Sanchez taking the ball for Philadelphia. Wyatt Langford shifts to center field while Sam Haggerty starts in left. Carter was limited to 63 big-league games last season and had a .728 OPS with five home runs and 14 steals.
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Red Sox's Marcelo Mayer: Sitting versus lefty
Mayer is out of the lineup for Thursday's Opening Day matchup with the Reds, Tim Healey of The Boston Globe reports.
Manager Alex Cora indicated earlier this week that Mayer would begin the season in a platoon at second base, so it's no surprise he's on the bench in favor of Isiah Kiner-Falefa with lefty Andrew Abbott on the mound for Cincinnati. Mayer had a .674 OPS over 44 regular-season games in his first taste of the majors last year and batted just .154 versus southpaws.
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Josh Hader RP | HOU
Astros' Josh Hader: Facing hitters by mid-April
Astros general manager Dana Brown said Thursday that Hader (biceps) will begin facing hitters by "mid-April," Brian McTaggart of MLB.com reports.
Working his way back from left biceps tendinitis, Hader has been throwing off the mound since early March and is slated for another bullpen session Friday. He's still a couple weeks away from facing hitters, though, and will surely need a rehab assignment before being activated, making it unlikely he'll be back before late April. Houston will use Bryan Abreu at closer while Hader is sidelined.