Wacha (illness) will be forced to miss his scheduled start Friday against the Brewers, Jaylon T. Thompson of The Kansas City Star reports.

Wacha is dealing with an apparent illness and as a result will now have his turn skipped in the Royals' rotation. The 34-year-old will shift his sights on being ready to go for his next tentative turn on the mound in Cleveland next week. In the meantime, Kansas City recalled Luinder Avila from Triple-A Omaha on Thursday, and he's expected to toe the rubber in the team's series opener against Milwaukee at home Friday.

Lodolo (blister) exited his minor-league rehab start with Single-A Daytona on Thursday in the third inning, Pat Brennan of The Cincinnati Enquirer reports.

Lodolo was looking to move past the blister on his left index finger by making one start with Single-A Daytona, but the blister reared its ugly head with two outs in the top of the third, forcing the southpaw out of the contest. The hope was that the 28-year-old would be able to return to the Reds in the coming days, but that now appears to be unlikely. Lodolo retired all eight batters he faced in order Thursday, striking out four in the process, and he finished having thrown just 40 pitches when he was scheduled to throw between 60 and 65.

Bailey isn't in the lineup for Thursday's game against the Mets, John Shea of the San Francisco Chronicle reports.

Bailey will take a seat Thursday after going just 2-for-18 (.111) with six strikeouts through his first six games of the year. Daniel Susac will catch instead for left-handed starter Robbie Ray, batting eighth.

The Marlins traded Acton to the Twins on Thursday in exchange for minor-league pitcher Logan Whitaker.

The 27-year-old righty was DFA'd by the Marlins on Sunday to make room on the 40-man roster for Leo Jimenez. Acton has pitched 2.1 scoreless innings in Triple-A to begin the season, and moving into a Twins organization that doesn't have much bullpen depth should help his chances of returning to the big leagues at some point.

The Giants recalled Tidwell from Triple-A Sacramento on Thursday, Alex Pavlovic of NBC Sports Bay Area reports.

After being sent down to Triple-A to begin the regular season, Tidwell will quickly receive a call-up to the majors to replace the injured Jose Butto (forearm). Tidwell, 24, gave up 15 earned runs over 15 innings with the Mets last year, but he kicked off the 2026 campaign by striking out three batters over 2.2 scoreless innings with Sacramento.

The Giants placed Butto on the 15-day injured list Thursday with right forearm fatigue, Alex Pavlovic of NBC Sports Bay Area reports.

Butto made an early exit from his appearance against the Padres on Wednesday due to a forearm issue, and he'll now spend at least the next couple of weeks on the injured list getting his forearm back to full strength. Blade Tidwell will come up from Triple-A Sacramento to take Butto's place in the bullpen.

The Rockies optioned Ritter to Triple-A Albuquerque on Thursday.

Ritter claimed a spot at the end of Colorado's bench to begin the regular season, but he'll now head back to Triple-A after beginning the season 1-for-7 with a run scored and three strikeouts. His demotion frees up a spot on the Rockies' active roster a day before Mickey Moniak (finger) is eligible to return from the injured list.

The Rockies recalled Bellozo from Triple-A Albuquerque on Thursday.

With Jose Quintana (hamstring) headed for the injured list, the Rockies will call upon Bellozo to fill the void in their starting rotation. The 26-year-old failed to make the Opening Day roster after posting a 6.32 ERA in the Cactus League, and he got off to a poor start in Triple-A by allowing three runs in three innings during his first outing with the Isotopes. It appears Bellozo will work out of the bullpen with Chase Dollander expected to start or work as a primary pitcher in place of Quintana on Saturday.

The Rockies placed Quintana on the 15-day injured list Thursday due to a right hamstring strain, retroactive to Monday.

Quintana allowed two earned runs over 4.1 innings during his Rockies debut on Sunday, but he appears to have come away from his start with a hamstring injury. He'll miss his next couple of turns through the rotation as a result, though it remains unknown if he'll need more than a minimum-length stay on the IL. Valente Bellozo was recalled from Triple-A Albuquerque in a corresponding move and figures to take Quintana's place in the rotation.

The Pirates optioned Cook to Triple-A Indianapolis on Thursday.

Cook will move to the minors in order to clear a spot on the active roster for top prospect Konnor Griffin, who is slated to make his MLB debut against the Orioles on Friday. The 27-year-old Cook slashed .245/.321/.379 across 380 plate appearances at Indianapolis last year, and he'd be a candidate to return to Pittsburgh if one of the big club's outfielders go down with an injury.