Andujar is out of the lineup for Wednesday's game against the Giants.

Andujar and Nick Castellanos shared the designated-hitter spot through the first five games, but neither player will be in the lineup Wednesday. Ramon Laureano will receive a day off from playing the outfield, but he'll stay in the starting nine at DH while Bryce Johnson takes his spot on defense. Andujar has struggled out of the gate thus far, going 2-for-12 with a walk and two RBI, so he'll need to raise his production in order to gain traction in the everyday lineup.

Castellanos is out of the lineup for Wednesday's game against the Giants.

Castellanos and Miguel Andujar shared the designated-hitter spot through the first five games, but neither player will be in the lineup Wednesday. Ramon Laureano will receive a day off from playing the outfield, but he'll stay in the starting nine at DH while Bryce Johnson takes his spot on defense. Castellanos has thus far gone 2-for-12 with a double and a walk, so he'll need to raise his production before solidifying an everyday role.

Pereira was removed from Wednesday's game against the Marlins ahead of the bottom of the fifth inning due to left ankle soreness.

Pereira struck out in both of his trips to the plate and may have tweaked the ankle while batting in the top of the fifth. Derek Hill stepped in as the replacement in right field for Pereira, whom the White Sox are viewing as day-to-day heading into their three-game series with Toronto that begins Friday.

McKinstry is out of the lineup for Wednesday's game against the Diamondbacks.

McKinstry had started in three of the Tigers' last four matchups against right-handed pitchers, but he'll take a seat Wednesday against righty Zac Gallen. The final spot in Detroit's everyday lineup versus righties looks like it could come down to McKinstry and Javier Baez, but neither player has done much in the early going to take control of a regular role. McKinstry has gone 1-for-8 with three strikeouts thus far, while Baez has two hits in 11 at-bats.

Yates (knee) threw an abbreviated bullpen session Wednesday, Jeff Fletcher of the Orange County Register reports.

Yates said afterward that his knee felt healthy but that he still needs to sharpen his stuff before he's ready to pitch in a game. Sidelined by left knee inflammation, Yates is eligible for activation from the 15-day injured list April 6. It's unclear whether he'll be back on that date, but if he isn't it shouldn't be long after. Jordan Romano has seized the Angels' closer job for the time being, but Yates could work his way back into that mix.

The Pirates are "deep into negotiations" on a contract extension with Griffin, but it's unclear how close the two sides might be toward reaching agreement on a deal, Buster Olney of ESPN.com reports.

Pittsburgh has been engaged in extension talks with its top prospect since early in spring training, with Olney noting that the Pirates have offered the 19-year-old shortstop a deal in the neighborhood of the eight-year, $111 million deal that Arizona's Corbin Carroll signed in the spring of 2023. Griffin's representatives, meanwhile, have been seeking a deal more on par with the eight-year, $130 deal Roman Anthony signed with the Red Sox last August. Griffin didn't break camp with the Pirates, but after smacking four home runs over his 16 Grapefruit League games, he's continued to thrive early on at Triple-A Indianapolis. Through his first four Triple-A games, Griffin has gone 6-for-13 with three doubles, two stolen bases and a 4:4 BB:K.

O'Hoppe is out of the lineup for Wednesday's game against the Cubs.

After catching each of the first two games of the series, O'Hoppe will receive a routine breather for a day game Wednesday. Travis d'Arnaud will handle catching duties for the Angels.

Schanuel is out of the lineup for Wednesday's game against the Cubs.

The left-handed-hitting Schanuel will sit for the first time this season while the Angels face off against a lefty (Matthew Boyd) for the series finale in Chicago. Jeimer Candelario will spell Schanuel at first base and will bat seventh Wednesday.

Lowe is out of the lineup for Wednesday's game against the Cubs.

The left-handed-hitting Lowe will sit for the first time this season while the Angels face off against a lefty (Matthew Boyd) for the series finale in Chicago. Bryce Teodosio will spell Lowe in left field and will bat ninth.

McMahon is not in the lineup for Wednesday's game against the Mariners.

The Yankees are facing a righty in George Kirby, but the left-handed-hitting McMahon will nonetheless begin the game on the bench. Amed Rosario is at third base and batting seventh in Wednesday's series finale.