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Trey Lance QB | LAC
49ers' Trey Lance: Uneven in first start
Lance completed 15-of-29 passes for 192 yards and an interception against Arizona on Sunday, adding 89 yards on 16 carries.
Coach Kyle Shanahan said after the game that Jimmy Garoppolo (calf) remains the starting quarterback when healthy, so whenever his health allows a return to the field, the 49ers appear intent to get him back into the starting lineup. San Francisco is 2-3 and any further losses in the short term could really harm their odds of making the playoffs. The 49ers have a bye in Week 6 before facing the Colts in Week 7, but it's not clear where Garoppolo will be in his recovery by then.
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Justin Fields QB | KC
Bears' Justin Fields: Leads team to victory
Fields completed 12 of 20 passes for 111 yards and a touchdown and registered four yards on three rushing attempts in the Bears' 20-9 win over the Raiders on Sunday.
With the Bears leading this game from the second quarter on, the team leaned on their defense and running backs to protect their lead. Even when Fields was throwing the ball, the majority of play calls were conservative, keeping Fields from using his big arm to stretch the defense. For fantasy, he'll be a matchup-dependent option who could have significant downside in games Chicago controls.
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Jared Goff QB | DET
Lions' Jared Goff: Struggles in losing effort
Goff completed 21 of 35 pass attempts for 203 yards, no touchdowns and one interception in Sunday's 19-17 loss to Minnesota.
Goff turned in the worst performance since joining the Lions this season, finishing with new lows in passing yards, completion percentage and yards per attempt. The former first-overall pick has seen his share of ups and downs through five contests, turning in three positive outings while failing to score a touchdown in the other two. Goff isn't currently an option to rely on in most standard fantasy formats heading into a matchup against the Bengals next Sunday.
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Davis Mills QB | HOU
Texans' Davis Mills: Shows promise in loss
Mills completed 21 of 29 passes for 312 yards, three touchdowns and no interceptions in Week 5 against the Patriots.
Mills combined to throw for 357 yards, two touchdowns and five interceptions across his first three professional starts. However, he delivered an impressive performance against the Patriots by both taking care of the ball and taking shots deep down the field. He connected with Chris Moore and Chris Conley to combine for four completions of 20 yards or more and also delivered his first multiple touchdown performance, tossing scores from 67, 37 and 11 yards. This lone performance may not change Mills' long-term outlook, though it does give the Texans' offense some life heading into a Week 6 matchup against the Colts.
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Kirk Cousins QB | LV
Vikings' Kirk Cousins: Solid, yet unspectacular in win
Cousins completed 25 of 34 pass attempts for 275 yards, a touchdown and an interception in Sunday's 19-17 win over Detroit.
Cousins turned in a fantasy performance that can't be complained about, nor celebrated, as it was spectacularly average across the board. It was a step in the right direction for the veteran arm, who turned in a dud against the Browns last game. Cousins will enter next week's tilt against the Cowboys with a solid 10:2 TD:INT ratio through five games.
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Taylor Heinicke QB | LAC
Football Team's Taylor Heinicke: Struggles against Saints
Heinicke completed 20 of 41 passes for 248 yards with zero touchdowns and two interceptions in Sunday's 33-22 loss to the Saints. He added 40 yards on five carries.
For the first time this season, Heinicke failed to produce a touchdown, and his 6.0 yards per attempt was by far a season low. The 28-year-old has a shaky 7:5 TD:INT through four starts, but he'll face a more generous defense in Week 6 when Washington hosts Kansas City.
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Mac Jones QB | SF
Patriots' Mac Jones: Works efficiently in win
Jones completed 23 of 30 passes for 231 yards, one touchdown and one interception in Sunday's 25-22 win over the Texans.
Jones didn't have a massive game from a stats perspective, but he methodically led the Patriots' offense to a victory. He spread targets around, as seven different receivers recorded multiple receptions. His longest completion went for 24 yards to Jakobi Meyers, and he delivered a 13-yard touchdown to Hunter Henry. Despite impressing five games into his rookie season, Jones' success on the field hasn't led to much fantasy value as he has only five total touchdowns and has yet to top 300 passing yards in a game.
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Jameis Winston QB | NYG
Saints' Jameis Winston: Tosses four TDs in win
Winston completed 15 of 30 passes for 279 yards and four touchdowns with one interception in Sunday's 33-22 win over Washington. He also gained 26 yards on six carries.
The quarterback was far from efficient and was somewhat lucky to have been picked off only once, but Winston connected on enough of his deep throws to put together his most productive performance of the year. Despite a lack of consistent passing yards week to week, he'll take a strong 12:3 TD:INT into the Saints' Week 6 bye.
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Daniel Jones QB | IND
Giants' Daniel Jones: Sustains concussion Sunday
Jones won't return to Sunday's contest at Dallas after suffering a concussion.
The diagnosis comes as no surprise after Jones took not only a helmet-to-helmet hit from a Dallas defender, but his helmet also hit the turf as he went to the ground. Afterward, he had trouble getting to and staying on his feet until Giants trainers got to him, and he required a cart to get to the locker room, where the concussion was confirmed. Now subject to league protocols for head injuries, Jones will yield quarterback duties for New York to Mike Glennon.
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Daniel Jones QB | IND
Giants' Daniel Jones: Requires cart to leave field
Jones (undisclosed) needed to be carted off the field near the end of the second quarter of Sunday's game in Dallas, Pat Leonard of the New York Daily News reports.
Jones took a quarterback keeper to the left and was met just before the goal line by two Cowboys defenders. His helmet took hits from both of those players and the turf, and he had difficulty getting to and staying on his feet before the Giants' training staff got to him. He likely is undergoing concussion testing and may soon be in the league's protocol for head injuries. As long as Jones is sidelined, Mike Glennon will direct the offense.