Goff completed 19 of 23 passes for 258 yards, three touchdowns and zero interceptions in Sunday's 37-24 win over the Bengals. He also had two rushes for minus-2 yards while losing a fumble.

Goff took advantage of a favorable matchup to turn in an extremely efficient performance. He completed four passes of 20 or more yards and averaged over 10 yards per attempt for the second time this season. Goff also delivered touchdowns from 10, 20 and 12 yards to account for his second performance with at least three scores. He'll face a stiffer Week 6 challenge against the Chiefs.

Herbert completed 22 of 29 pass attempts for 166 yards, one touchdown and one interception while taking four carries for 60 yards in Sunday's 27-10 loss to the Commanders.

Herbert did not look comfortable in the pocket without starting left tackle Joe Alt (ankle) on Sunday, finishing below 200 yards passing for the first time this season. The 27-year-old was sacked four times while throwing his fourth interception of the season, all of which have come during his current three-game skid. Things got so bad that head coach Jim Harbaugh turned to backup QB Trey Lance in garbage time of Sunday's loss. Herbert did salvage his fantasy day a bit by providing managers with a season high of 60 yards on the ground. The talented signal-caller will attempt to get his season back on track against the fledgling Dolphins next Sunday.

Fields completed 32 of 46 passes for 283 yards and two touchdowns in Sunday's 37-22 loss to the Cowboys. he added 26 rushing yards on seven carries.

His final numbers look good, but both TDs came in the fourth quarter after the game was well out of reach, and the Dallas pass rush gave Fields fits all afternoon as he got sacked five times and took another nine QB hits. Fields has produced multiple scores in back-to-back games since returning from a concussion, but he'll remain a volatile fantasy option in Week 6 against a tough Broncos defense.

Rattler completed 21 of 31 passes for 225 yards and a touchdown in Sunday's 26-14 win over the Giants. He added 21 rushing yards on six carries.

The second-year QB led the Saints to their first win of the season with another relatively quiet, but turnover-free, performance. Rattler was able to pick his spots against a poor Giants secondary, connecting with Rashid Shaheed on an 87-yard catch-and-run TD in the second quarter. Rattler doesn't appear to be in much danger of losing his starting job to rookie Tyler Shough despite the team's 1-4 record, posting a 6:1 TD:INT and 67.2 percent completion rate, albeit with a poor 5.6 YPA. He'll look to build on this performance in Week 6 against the Patriots.

Darnold completed 28 of 34 pass attempts for 341 yards, four touchdowns and one interception in Sunday's 38-35 loss to the Buccaneers.

Darnold's untimely interception in the closing moments of Sunday's narrow loss could not erase the gaudy passing numbers he provided fantasy managers Sunday. It was the 28-year-old's first start this season eclipsing the 300-yard mark in passing, and the most comfortable he has looked running Seattle's offense through five starts. Darnold will attempt to combine strong results with a Seahawks win in a road matchup against the Jaguars next Sunday.

Smith completed 25 of 36 passes for 228 yards with no touchdowns and two interceptions while adding three carries for eight yards in the Raiders' 40-6 loss to the Colts on Sunday.

The left half of Smith's stat line looked perfectly acceptable, but the two picks, four sacks and quarterback rating of 18.9 that comprise the rest of his numbers all underscore how difficult the afternoon was. The Raiders' day actually started off in encouraging fashion via a marathon 16-play, 80-yard drive that consumed 9:50 of the first quarter, but that ultimately culminated in a field goal. The next five possessions would feature a blocked punt, both of Smith's interceptions, a punt and a missed field goal, helping dig Las Vegas into a hole it couldn't recover from. Smith has now thrown nine interceptions over his first five games at the helm of the Raiders' offense, including three contests in which he's tossed multiple picks. Nevertheless, Smith will continue under center, potentially without Brock Bowers (knee) once again, when the Raiders welcome in the Titans for a favorable Week 6 home clash.

Daniels completed 15 of 26 pass attempts for 231 yards and a touchdown while rushing for 39 yards on eight attempts in Sunday's 27-10 win over the Chargers.

Daniels returned from a two-week absence due to a knee injury in order to lead his team to its third win of the season. The 24-year-old was sporting a brace on his left knee, but it did not appear to limit the quarterback's mobility on any of his eight carries Sunday. Daniels is averaging 221.3 passing yards and 41.3 rushing yards with four touchdowns to no interceptions in three 2025 starts. The dual-threat sophomore could be primed for his finest fantasy outing under the bright lights of Monday Night Football in Week 6 when the Commanders host a Bears defense that is surrendering 389.0 yards of offense to opponents this season.

Young completed 19 of 30 passes for 198 yards with two touchdowns and one interception while adding three carries for one yard in the Panthers' 27-24 win over the Dolphins on Sunday. He also lost a fumble.

Carolina managed to pull off a comeback from a 17-0 deficit, but Young had an uneven day that included three sacks in addition to his two turnovers. Rico Dowdle also helped carry the offense with his 206-yard, one-touchdown effort, but Young played a key part with a seven-yard touchdown pass to Xavier Legette that kickstarted the rally late in the first half, and he added a four-yard toss to Mitchell Evans that proved to be the game-winning score. Young has thrown for under 200 yards in all but one game this season, so even with the encouraging team result for the Panthers on Sunday, he remains a somewhat shaky fantasy option even in a favorable Week 6 home matchup against the Cowboys.

Nix completed 24 of 39 passes for 242 yards with a touchdown and no interceptions while adding three rushes for 22 yards in the Broncos' 21-17 win over the Eagles on Sunday. He also threw a two-point conversion pass.

Nix had his fair share of struggles against the Eagles' talented defense, but he helped lead Denver back from a 17-3 second-half deficit. Nix led a trio of fourth-quarter scoring drives, capping one of them with an 11-yard touchdown pass to Evan Engram and following it up with a two-point conversion toss to Troy Franklin. Nix has at least one touchdown pass in every game thus far this season and has posted his two highest passing yardage totals of the campaign in the last pair of contests heading into a Week 6 trip across the pond to face the Jets in London.

Tagovailoa completed 27 of 36 passes for 256 yards with three touchdowns and no interceptions and added one rush for five yards in the Dolphins' 27-24 loss to the Panthers on Sunday.

Tagovailoa managed well in his first game without Tyreek Hill (IR, knee), focusing a majority of his attention, as expected, on the trio of Jaylen Waddle, Darren Waller and De'Von Achane. The three pass catchers were responsible for Tagovailoa's three TD tosses and 17 of his completions overall. The 2020 first-round pick has multiple touchdown passes in four straight games -- and Sunday's tally was a season high -- but with Miami at 1-4, the overall long-term outlook for the Dolphins is bleak. A Week 6 home matchup against the Chargers could be an uphill battle for the short-handed offensive unit as well, even when factoring in Los Angeles' struggles against the Commanders in Week 5.