Brissett completed 19 of 32 pass attempts for 168 yards, one touchdown and one interception while adding three rushing yards and a lost fumble on two carries in Sunday's 30-13 loss to the 49ers.

Brissett earned head coach Jerod Mayo's vote of confidence prior to Sunday's lopsided loss, but three fumbles (one lost) and a pick-six might have the veteran back on the hot seat. The two-time Patriot has provided just two touchdowns against two turnovers through four starts with the club that initially drafted him in 2016. Even if Brissett remains the starter for a 1-3 New England squad, he doesn't inspire confidence as a fantasy option against the Dolphins in Week 5.

Mahomes completed 19 of 29 passes for 245 yards, one touchdown and one interception in Sunday's 17-10 win over the Chargers.

Mahomes showed impressive efficiency by averaging 8.5 yards per attempt, though it didn't lead to a strong fantasy showing. The latter is understandable given that the Chiefs lost another key pass catcher after Rashee Rice (knee) went down, leaving Travis Kelce and rookie Xavier Worthy as Mahomes' top two targets. The highlight of his performance came late in the second quarter when he found Worthy for a 54-yard touchdown. With Rice and Hollywood Brown (shoulder) both sidelined for the long term, it may be difficult for Mahomes to turn in his typical fantasy performances on a regular basis.

Minshew completed 14 of 24 passes for 130 yards, no touchdowns and no interceptions in Sunday's 20-16 win over the Browns. He also had two rushing attempts for minus-2 yards.

Minshew held onto the starting job after the Raiders mulled replacing him with Aidan O'Connell, and Minshew justified that decision by managing Vegas to victory. While Minshew's performance wasn't impressive statistically, he avoided major mistakes while the Raiders went run-heavy in the absence of star wide receiver Davante Adams (hamstring). Minshew may not be asked to do significantly more in Week 5 against the stout Denver defense, especially if Adams remains unavailable.

Fields completed 22 of 34 passes for 312 yards, one touchdown and no interceptions in Sunday's 27-24 loss to the Colts. He added 10 rushes for 55 yards and two additional touchdowns.

Fields got off to a shaky start as the Steelers went scoreless for their first four offensive possessions, leading to a 17-3 deficit at halftime. That forced Pittsburgh into opening up the offense, leading to Fields throwing for 192 yards and rushing for 41 in the final two quarters. He did make a few key mistakes, highlighted by taking a sack that led to a lost fumble in the middle of the third quarter. On the other hand, he nearly led a substantial comeback and showed his dynamic playmaking ability as both a rusher and passer with five completions of 20 or more yards. He still has yet to officially be named the Steelers' starting quarterback, but it would come as a surprise if he isn't under center for a Week 5 matchup against the Cowboys.

Watson completed 24 of 32 pass attempts for 176 yards, one touchdown and one interception while rushing eight times for 32 yards in Sunday's 20-16 loss to the Raiders.

Watson failed to eclipse the 200-yard mark in passing in all four of his starts this season. With a mediocre 5:6 touchdown-to-turnover ratio in those four contests, the former fantasy star is looking like a shell of his former self in three seasons with Cleveland. Managers still holding out hope for the 2017 first-round pick are likely playing in deeper formats or two-QB leagues, as Watson is unlikely to garner big projections in a road matchup against Washington following a forgettable start to 2024.

Murray completed 16 of 22 passes for 142 yards and a touchdown in Sunday's 42-14 loss to the Commanders. He added one rushing attempt for three yards.

After capping the opening drive with a two-yard touchdown pass to Marvin Harrison, Murray was surprisingly quiet the rest of the way as both a passer and a runner against a beatable Washington defense as the Cardinals felt the absence of starting tight end Trey McBride (concussion). Prior to Sunday's dud as a runner, Murray had at least 45 rushing yards in every game this season and had rushed for at least 20 yards in eight consecutive starts. Murray's averaging just 194.3 passing yards per game heading into a Week 5 road game against the 49ers.

Stroud completed 27 of 40 passes for 345 yards and two touchdowns in Sunday's 24-20 win over the Jaguars. He added 17 rushing yards on three carries.

The Texans trailed for most of the fourth quarter in a back-and-forth affair, but Stroud led a game-winning drive in the final three minutes that was capped by a one-yard TD toss to Dare Ogunbowale. It's Stroud's first game this season with more than 260 passing yards, but increased volume helped, as his 40 pass attempts were also a season high. The second-year QB figures to be very busy again in Week 5 as the Texans host the Bills.

Daniels completed 26 of 30 passes for 233 yards, one touchdown and one interception in Sunday's 42-14 win over the Cardinals. He added eight rushing attempts for 47 yards and a touchdown. Daniels also threw a two-point conversion.

Daniels has completed 47 of 53 passes while leading the Commanders to 80 points over the last two weeks. The rookie second overall pick scored his fourth rushing touchdown on a nine-yard run early in the third quarter, then threw his third passing touchdown of the campaign with a 10-yard pass to Terry McLaurin in the fourth. Daniels has taken the NFL by storm with his mix of elusiveness and accuracy, and he'll look to keep rolling in Week 5, when the 3-1 Commanders host the 1-3 Browns.

Purdy (back) completed 15 of 27 pass attempts for 288 yards, one touchdown and one interception in Sunday's 30-13 win over the Patriots.

Purdy and his teammates took care of business in a favorable home matchup Sunday. The end results were modest from a fantasy perspective, with San Francisco passing for just one touchdown in the lopsided team win. Purdy was dealing with back soreness coming off of last week's three-touchdown performance, which might help explain his poor completion percentage (56.0 percent) compared to his 69 percent completion rate in two-plus years as a pro. The rising star continues to be a strong fantasy option heading into another favorable home matchup against the Cardinals on Sunday.

Lawrence completed 18 of 33 passes for 169 yards and two touchdowns in Sunday's 24-20 loss to the Texans. He also rushed three times for five yards and committed a fumble recovered by Jacksonville.

Despite another meager yardage total, Lawrence tossed multiple TDs in a game for the first time this season, hitting rookie Brian Thomas for a two-yard strike in the first quarter and Christian Kirk for an eight-yard score in the third. The latter gave the Jaguars a 20-17 lead, which looked like it might hold up until the team's defense failed to stop C.J. Stroud on the Texans' final drive. Lawrence will try to finish the job and give Jacksonville its first win of 2024 in Week 5 against Indianapolis.