The Bengals activated Burrow (toe) from injured reserve Wednesday.

Reports a few weeks ago said Burrow was targeting the Thanksgiving Day game at Baltimore for his return to action. It's now playing out that way, with Burrow having been officially activated after being listed as a full practice participant Monday and Tuesday. He may not have his usual mobility, and definitely won't have Tee Higgins (concussion), but Burrow nonetheless remains a weekly candidate to lead the league in pass attempts and yardage. He said Tuesday that he plans to continue playing down the stretch this season even if it becomes clear that Cincinnati's slim playoff hopes have dwindled to nothing, ESPN's Ben Baby reports.

Coach Kevin O'Connell said McCarthy has made enough progress through the concussion protocol to practice in a limited capacity Wednesday, Dane Mizutani of the St. Paul Pioneer Press reports.

McCarthy reported symptoms of a head injury on the flight back to Minnesota from Green Bay on Sunday, which spurred the Vikings to place him in the concussion protocol. His ability to log at least individual drills at Wednesday's practice would seem to give him a chance to be available for Sunday's game at Seattle, but backup Max Brosmer is handling all the first-team reps at the beginning of Week 13 prep.

Stroud (concussion) participated in practice Wednesday, Aaron Wilson of KPRC 2 Houston reports.

The Texans' upcoming injury report will reveal Stroud's official participation level, but Wilson indicates that the QB is expected to clear the NFL's concussion protocol at some point this week. Stroud has missed three straight games, but in the event that he is cleared for Week 13 action, Davis Mills -- who has gone 3-0 while filling in -- would be in line to return to working as Houston's No. 2 signal caller.

Buccaneers head coach Todd Bowles said Wednesday that Bridgewater will get most of the starting reps at practice in preparation for Sunday's contest against the Cardinals, but that Baker Mayfield (AC joint) has not yet been ruled out, Scott Smith of the team's official site reports.

Bridgewater replaced Mayfield at halftime during Tampa Bay's 34-7 loss to the Rams in Week 12, at which point the game was already well out of contention. As a result Bridgewater completed just eight of 15 passes for 62 yards versus a dominant Los Angeles defense, but the veteran signal-caller will carry more preparation into Sunday's home game against Arizona if he's called upon to start. Mayfield is dealing with a low-grade AC joint sprain in his left shoulder and will be re-evaluated closer to the end of the practice week, per Mike Garafolo of NFL Network.

Giants interim coach Mike Kafka said Dart will practice in full Wednesday but is still officially in the NFL's concussion protocol, Evan Barnes of Newsday reports.

Dart has missed two consecutive games while progressing through the concussion protocol, and though beginning his preparation for Week 13 as a full participant is a good sign that he'll gain clearance in time to play Monday versus the Patriots, Kafka declined Wednesday to commit to the rookie signal-caller's availability, per Pat Leonard of the New York Daily News. Top backup Jameis Winston and Dart will split first-team reps at practice Wednesday, Jordan Raanan of ESPN.com reports. Dart will need to gain full clearance from the concussion protocol, including from an independent neurologist, in order to be eligible to play Monday.

Falcons head coach Raheem Morris said that Penix (knee) underwent full reconstructive surgery to address the partially torn ACL in his left knee on Tuesday and experienced no complications with the procedure, D. Orlando Ledbetter of The Atlanta Journal-Constitution reports.

Penix faces a nine-month recovery timetable as a result of the procedure. The 25-year-old quarterback has now undergone ACL reconstructive surgeries three times in his career, as he previously had procedures on his right knee in 2018 and 2020 while in college. He also suffered season-ending injuries to each shoulder in 2019 and 2021. Morris has said that the severe nature of Penix's injury will "100 percent" influence Atlanta to "make some different plans" at quarterback this offseason, per Adam Schefter of ESPN, though that could just as easily refer to the team prioritizing a reliable backup rather than bringing in actual competition for the starting role. Kirk Cousins will start the remainder of the season under center for the Falcons, but this offseason the team can exercise a potential 'out' for the final two season of his four-year, $180 million contract at the cost of a $35 million dead-cap hit. Atlanta doesn't currently hold any first-round picks in the 2026 NFL Draft, which will limit the team's ability to maneuver in pursuit of a high-upside alternative at quarterback.

Coach Shane Steichen said that Jones (fibula) will be listed as limited on Wednesday's practice estimate, but added that the QB will "be good to go this week," James Boyd of The Athletic reports.

Jones popped up on the Colts' Week 12 injury report when he was limited last Thursday before working fully Friday and suiting up for the team's 23-20 overtime loss to the Chiefs on Sunday. While he continues to manage a fibula injury, Jones remains on track to be available this weekend against the Texans, a notion that would be supported by the QB being listed as a full practice participant by Friday.

Mayfield (shoulder) is dealing with a low-grade AC joint sprain and has a chance to be available Sunday versus the Cardinals, Ian Rapoport of NFL Network reports.

Mayfield's availability for Week 13, or lack thereof, will largely come down to pain management, per Rick Stroud of the Tampa Bay Times, so it will be encouraging if he's able to show up as at least a limited participant on Wednesday's practice report. Per Stroud, Mayfield is participating in the early portion of Wednesday's walkthrough. Overall, though, it's a relief for the Buccaneers' offense that Mayfield's MRI on Monday didn't reveal worse than a low grade sprain. Teddy Bridgewater remains on hand to start versus Arizona in the event that Mayfield isn't cleared to play.

Flacco (shoulder/finger) was a full participant in Tuesday's practice.

Flacco was considered limited on Monday's estimated injury report while managing a pair of injuries, but he's now on track to be available for Thursday's matchup with the Ravens. With Joe Burrow (toe) expected to return from injured reserve following a nine-game absence, Flacco will be in line for No. 2 quarterback duties against Baltimore.

Burrow (toe) was a full participant at practice Tuesday.

Burrow has now been listed as a full participant on four of the Bengals' last five practice reports. The quarterback remains on injured reserve for the time being, but assuming his surgically repaired toe holds up well coming out of Tuesday's session, the Bengals could confirm Wednesday that he'll return to action Thursday against the Ravens. Burrow has sat out Cincinnati's last nine games following surgery.