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Ty Johnson RB | BUF
Bills' Ty Johnson: No-go Week 1
Johnson (hamstring) is inactive Week 1 against the Texans.
Johnson was able to log only a single limited practice this week, and the 28-year-old back entered Sunday with a "questionable" tag. He'll ultimately sit against Houston, leaving a few more backfield snaps to starter James Cook and backup Ray Davis. Johnson and the Bills have a short week ahead, as they're set to take on the Lions in a Week 2 matchup Thursday night. If Johnson does end up suiting up then, he'll likely return to his role as a passing down specialist and special-teamer, similar to his last few seasons in Buffalo.
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Josh Jacobs RB | GB
Packers' Josh Jacobs: Time on exempt list could equal time served
Jacobs (personal) remains on the Commissioner's Exempt List, but the NFL may count time on the list as time served if it eventually issues a suspension to the running back, Adam Schefter of ESPN reports.
Jacobs made an appearance in court Thursday and pleaded no contest to misdemeanor charges of battery and criminal damage to property in a case stemming from a May domestic violence incident. There still are some moving parts related to the case, so it's unclear when exactly the NFL may issue a suspension, but Jacobs will continue to miss practices and games as long as he's on the Commissioner's Exempt List.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Not expected to play Week 1
Kamara (knee), who is listed as questionable for Sunday's game in Detroit, isn't in line to play in the season opener and is instead slated to make his 2026 debut Week 2 at Baltimore, Nick Underhill of NewOrleans.Football reports.
Kamara departed a joint practice with the Cowboys on Aug. 18 early and was diagnosed with an MCL sprain that was expected to sideline him for one month. While he followed up back-to-back limited sessions to begin Week 1 prep with a full practice Friday, the Saints will exercise caution with the 10th-year pro and allow him another week to get healthier. In Kamara's anticipated absence Sunday, New Orleans will roll with Travis Etienne as its lead runner, with Kendre Miller and practice-squad call-up CJ Donaldson the other candidates for backfield reps.
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Jeremiyah Love RB | ARI
Cardinals' Jeremiyah Love: Expected to make NFL debut Sunday
Love (ankle) remains listed as questionable but is expected to play in Sunday's game at the Chargers, Ian Rapoport of NFL Network reports.
Love initially suffered a high-ankle sprain during preseason Week 1, and after practicing in a limited fashion from Wednesday through Friday, he entered the weekend as questionable to suit up. Josh Weinfuss of ESPN.com reported Friday that Love was trending toward making his debut Sunday, and Rapoport's report indicates that the rookie third overall pick indeed will avoid the Cardinals' list of Week 1 inactives. Such a decision will become known about 90 minutes before a 4:25 p.m. ET kickoff, but considering his lack of activity over the last month, Love may well be eased into his first NFL action while working in tandem with fellow running back Tyler Allgeier.
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DeeJay Dallas RB | MIN
Vikings' DeeJay Dallas: Elevated for Sunday
The Vikings elevated Dallas from the practice squad to the active roster Saturday, Craig Peters of the team's official site reports.
Dallas signed with the Vikings on Sept. 2 after being released by the Jaguars during cutdown day. The running back will likely provide a special teams presence in Sunday's game against the Packers with minimal offensive usage.
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Josh Williams RB | TB
Buccaneers' Josh Williams: Elevated to active roster
The Buccaneers elevated Williams from the practice squad to the active roster Saturday.
Williams is set to suit up as a reserve running back for the Buccaneers' Sunday contest against the Bengals. The rusher will likely take reserve snaps behind Bucky Irving and Kenny Gainwell in place of Sean Tucker (hamstring), who is doubtful to play in Sunday's game.
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Frank Gore Jr. RB | BUF
Bills' Frank Gore: Elevated for Sunday
The Bills elevated Gore from the practice squad to the active roster Saturday.
Gore has been a practice squad staple for the Bills over the past two years. The running back has likely been elevated to the active roster as a depth precaution for a scenario in which Ty Johnson (hamstring) cannot suit up for Sunday's game against the Texans. If Johnson is good to go, Gore will likely be inactive on game day.
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Kene Nwangwu RB | NYJ
Jets' Kene Nwangwu: Out for Sunday
Nwangwu (back) has been ruled out ahead of Sunday's game against the Titans.
Nwangwu was designated as doubtful after Friday's practice, so the eventual ruling that he will not suit up for Sunday's contest is not surprising. The depth running back and primary kick returner for the team continues to deal with a back injury he likely suffered during a practice session earlier in the week. With Nwangwu out, wide receiver Isaiah Williams will likely add kick return duties alongside his punt return duties in Sunday's game.
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Israel Abanikanda RB | DAL
Cowboys' Israel Abanikanda: Signs with active roster
The Cowboys signed Abanikanda from the practice squad to the active roster Saturday.
Abanikanda joined up with the Cowboys' practice squad after being waived by the team Aug. 30. The running back will now get a shot at a depth role on the active roster due to the placement of Malik Davis (hip) on IR. Javonte Williams and Emari Demercado will likely see most of the offensive action, but Abanikanda could acquire a few carries alongside a moderate special teams workload.
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CJ Donaldson RB | NO
Saints' CJ Donaldson: Elevated for Sunday
The Saints have elevated Donaldson from the practice squad to the active roster ahead of Sunday's game against the Lions, Ross Jackson of WWL Louisiana reports.
Donaldson signed with the Saints' practice squad Sept. 2 after being a casualty of the team's Aug. 30 cuts. The running back will fill in for Audric Estime (thigh) as a reserve option behind Travis Etienne, Alvin Kamara (knee), and Kendre Miller while Estime recovers from his thigh issue on IR.