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Tyjae Spears RB | TEN
Titans' Tyjae Spears: Inactive for Sunday's game
Spears (knee) is listed as inactive Sunday against the Browns.
Beginning during Week 3 prep, Spears has experienced practice restrictions most weeks due to first an ankle injury and currently a knee issue. He's been able to suit up for each of the last four games but played second fiddle to Tony Pollard out of the Titans backfield, turning eight carries and 11 catches (on as many targets) into 47 yards from scrimmage. Now that Spears is confirmed to be unavailable, though, the active RBs behind Pollard on Sunday are Julius Chestnut, Michael Carter and Kalel Mullings.
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Baker Mayfield QB | TB
Buccaneers' Baker Mayfield: Cleared to start Week 7
Mayfield (thumb) is active for Sunday's game against the Panthers.
Following a three-game absence, Mayfield returned to practice this week as a full participant from Wednesday through Friday. Tampa Bay still elected to list him as questionable heading into Sunday, but Mayfield's availability was never in any peril after he experienced no setbacks with his dislocated right thumb throughout the week. Though he'll be back under center for the first time since Week 3, Mayfield will be wearing a specialized glove on his right hand that offers added support to the injured joint in his thumb, per Scott Smith of the Buccaneers' official site. Mayfield will be returning to the lineup without his top target at his disposal, as wideout Emeka Egbuka (concussion/foot) has been ruled out.
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Elijah Sarratt WR | BAL
Ravens' Elijah Sarratt: Won't play against Cincinnati
Sarratt (coach's decision) is inactive for Sunday's game against the Bengals.
Saratt will be sidelined for six of the Ravens' first seven games of the regular season. His next chance to play is Week 8 against the Bills on Nov. 1, but it looks like the rookie fourth-rounder won't have a role in the offense unless another receiver were to miss time.
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Justin Reid S | NO
Saints' Justin Reid: Ruled out with concussion
Reid (concussion) has been ruled out for the remainder of Sunday's game against the Steelers in Paris.
Reid sustained a concussion in Sunday's international game and will not return to the contest. The safety has entered the NFL's five-step concussion protocol and will need to be cleared by an independent neurologist for every step of his return journey.
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Josh Jacobs RB | GB
Packers' Josh Jacobs: May not get full workload Sunday
Jacobs is expected to start in his season debut Sunday against the Lions, but the extent of his role is likely to be decided upon as the game unfolds, according to Jay Glazer of Fox Sports.
While he spent the first six weeks of the season on the commissioner's exempt list, Jacobs was still allowed at the Green Bay facility and was able to stay on top of his conditioning, but he wasn't cleared to resume practicing with the team until Wednesday. After a full week of drills, the Packers were comfortable enough with activating Jacobs for Sunday, but the team plans to "keep an eye on him" and may not be ready to hand him his normal workload right off the bat. In the weeks to come, Jacobs shouldn't have much trouble reclaiming a three-down workhorse role, given the struggles of Green Bay's other running backs in generating production over the first six games of the season.
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CJ Donaldson RB | NO
Saints' CJ Donaldson: Won't return in Paris
Donaldson (shoulder) has been ruled out for the rest of Sunday's game against the Steelers in Paris, Jeff Nowak of The Big 870 New Orleans reports.
Donaldson sustained a shoulder injury during the first quarter of Sunday's game, and the injury is severe enough for him to be sidelined for the rest of the contest. Alvin Kamara and Kendre Miller will be the Saints' two remaining running backs the rest of the way in Donaldson's absence.
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Jaylon Moore OT | KC
Chiefs' Jaylon Moore: Won't play against Seattle
Moore (concussion) has been ruled out for Sunday's game against the Seahawks.
Moore entered the league's concussion protocol during the Chiefs' Week 6 against the Chargers. He was not cleared to practice during Week 7 prep and will be sidelined for Sunday's contest, so Joshua Ezeudu will likely draw the start at right tackle. Moore's next opportunity to play is Week 8 against the Broncos on Nov. 1.
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Nick Emmanwori SAF | SEA
Seahawks' Nick Emmanwori: Optimism for Sunday Night Football
The Seahawks expect that Emmanwori (hip) will play against the Chiefs on Sunday, Ian Rapoport of NFL Network reports.
Emmanwori popped up on Friday's report as a limited practice participant due to a new hip injury. Despite the new health concern, the second-year defensive back is trending toward being available for Sunday's contest. Emmanwori has accumulated 20 tackles (15 solo), including 2.0 sacks, and one pass defense over his last three games.
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Uchenna Nwosu LB | SEA
Seahawks' Uchenna Nwosu: Expected to suit up against Kansas City
Ian Rapoport of NFL Network reports that Nwosu (hip) is expected to be cleared to play against the Chiefs on Sunday.
Nwosu popped up on Thursday's injury report as a limited practice participant due to a hip injury. His practice reps were restricted again Friday, but it looks like the veteran linebacker will be a go for Sunday night's contest. Nwosu has accumulated 15 tackles (nine solo), including 1.0 sacks, three pass defenses and one forced fumble through six regular-season games.
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Budda Baker S | ARI
Cardinals' Budda Baker: Should play Week 7
Baker (groin) is listed as questionable but expected to play against the Broncos on Sunday, Ian Rapoport of NFL Network reports.
Baker missed the first two practices of the week due to both an illness and groin injury before logging a limited session Friday. That was enough for him to draw the questionable tag for Week 7, and it appears the veteran safety will suit up against Denver.