Seymour will start at first base and bat eighth in Wednesday's game against the Blue Jays, Marc Topkin of the Tampa Bay Times reports.

Seymour appears to have re-emerged as the Rays' preferred option at first base, as he'll pick up his fourth start in Tampa Bay's last five matchups with right-handed pitchers. The rookie is still slashing a lowly .208/.236/.321 over 55 plate appearances in the majors this season and will be at risk of losing out on his strong-side platoon role if Jonathan Aranda (wrist) returns from the injured list next week.

Burger is absent from the lineup for Wednesday's game in Houston.

Burger has swung a hot bat since coming off the injured list earlier this month, but he went 0-for-7 with five strikeouts in the first two games of the series and will now get a day off to regroup. Rowdy Tellez will play first base and bat cleanup as the Rangers try to avoid the sweep.

Sogard is absent from the lineup for Wednesday's game versus the Athletics.

Sogard had started five of the last seven tilts, seeing action at both second base and right field. He'll take a seat Wednesday, as Romy Gonzalez will occupy the keystone and Rob Refsnyder will patrol right field.

Clemens is absent from the lineup for Wednesday's game against the Yankees.

The Yankees are sending righty Luis Gil to the bump, marking the first time over the last six contests versus righties that Clemens has been out of the lineup. Edouard Julien will handle first base and bat eighth in the series finale.

Mountcastle is out of the lineup for Wednesday's game against the White Sox.

Mountcastle is on the bench for the fourth time in five games and looks like he'll be limited to a part-time role down the stretch. Since returning from the injured list Aug. 8, Mountcastle has posted a .702 OPS, nearly 100 points above Coby Mayo's mark during that same stretch (.612 OPS). However, because Mayo is seen as a core building block for the Orioles, he'll continue to be prioritized as the team's everyday first baseman ahead of Mountcastle, who is entering his final year of arbitration in 2026 and could be a possible trade or non-tender candidate this offseason.

The Cardinals placed Contreras on the 10-day injured list Wednesday with a right shoulder strain.

The injury had previously been labeled as a biceps strain, but either way, it will end Contreras' season. He slashed .257/.344/.447 with 20 home runs and 80 RBI over 135 games in his first season as a full-time first baseman. Alec Burleson will take over at first base for the Cardinals down the stretch, which should lead to more playing time in the outfield for Jordan Walker.

Yorke will start in right field and bat seventh in Wednesday's game against the Cubs.

Yorke will stick in the lineup for the fifth straight contest and for the seventh time in eight games. He's yet to take advantage of receiving ample playing time in September, as he's slashing just .167/.189/.222 with no home runs, one stolen base, five RBI and one run in 37 plate appearances since being recalled from Triple-A Indianapolis at the start of the month.

Horwitz is out of the lineup for Wednesday's game against the Cubs.

The left-handed-hitting Horwitz will hit the bench for the series finale while the Cubs send southpaw Matthew Boyd to the bump. Rafael Flores will step in for Horwitz on Wednesday to make his first MLB start.

Steer (neck) will start at first base and bat seventh in Wednesday's game versus the Cardinals.

Steer had been scheduled to start Monday's game but was scratched due to neck spasms. However, he had a chiropractic adjustment Tuesday and is ready to play in Wednesday's series finale. Steer has been losing reps to Sal Stewart at first base, but Stewart will handle third base in Wednesday's contest.

The Cardinals will place Contreras (biceps) on the 10-day injured list Wednesday with a right biceps strain, Katie Woo of The Athletic reports.

The strain is considered mild, but it is bad enough to end the first baseman's season with less than two weeks remaining. Contreras will finish 2025 with a .257/.344/.447 batting line, 20 home runs and 80 RBI over 135 games. Alec Burleson will take over as the team's everyday first baseman down the stretch, opening up more playing time in the outfield for Jordan Walker and others.