Alvarez left Sunday's game against the Angels with an apparent right leg injury, Matt Kawahara of the Houston Chronicle reports.

Alvarez doubled in the bottom of the third inning, but he came up favoring his right leg after sliding into the second-base bag. He left the game after a visit from the trainer, and with Houston thinking big picture, the team could opt to rest the slugger for a game or two even if this turns out to be minor.

Manzardo is not in Sunday's lineup against the Cardinals.

The lefty-hitting designated hitter will head to the bench, even with righty Andre Pallante on the hill for St. Louis. Manzardo went 0-for-5 with a walk and two strikeouts in the first two games of the series. Jose Ramirez is starting at DH while Angel Martinez gets the nod at third base.

Stanton went 2-for-4 with a three-run home run, an additional run and a walk in Saturday's 10-0 win against Oakland.

Stanton came into Saturday having gone 12 games without a long ball and batting .122 with a 36.2 percent strikeout rate over that stretch. The veteran slugger shook the slump with a 441-foot, three-run blast in the third inning and reached two other times in the rout, notching his first multi-hit game since Sept. 1. Stanton is up to 26 home runs and 67 RBI on the season with a .234/.297/.476 slash line over 435 plate appearances.

Alvarez went 4-for-5 with a home run, a double and two total runs in Saturday's 10-4 win against the Angels.

Alvarez's most productive hit was a solo shot to center field in the seventh inning. That was his 35th long ball of the season, 10th most in the majors. The four-hit performance snapped an uncharacteristic cold streak for Alvarez, who came into Saturday having gone 2-for-22 over his previous six games.

O'Hearn isn't in Baltimore's lineup Friday against the Tigers.

With southpaw Tyler Holton set to open Friday's contest for Detroit, the lefty-hitting O'Hearn will take a seat on the bench. While he rests, Coby Mayo will pick up a start at first base and bat seventh.

Yoshida is absent from the lineup for Friday's game against the Twins.

The Twins are starting a right-hander in David Festa, but the left-handed-hitting Yoshida will nonetheless begin this one on the bench. After an excellent July and August, Yoshida is slashing just .231/.286/.365 so far in September. Tyler O'Neill will be Boston's designated hitter Friday.

Manzardo went 3-for-3 with a solo home run in Thursday's 3-2 win over Minnesota.

Manzardo opened the scoring in the bottom of the first inning with a solo shot off Simeon Woods Richardson. The 24-year-old Manzardo has swung the bat well since he was recalled on Sep. 1, going 15-for-42 (.357) with four homers in 16 games after batting just .207 with a .571 OPS across 30 contests in his first stint with the Guardians earlier this year.

Rooker went 2-for-3 with an RBI infield single, a stolen base and a walk in a win over the Cubs on Wednesday. He was also caught stealing on another attempt.

Rooker continued his torrid September run Wednesday with his eighth multi-hit effort in 17 games. The slugger got it done with some small ball in the matinee victory after having belted his 36th and 37th home runs of the season on back-to-back days to begin the week. Rooker's on-base streak now sits at 28 games as well, a stretch that dates back to Aug. 20 and has seen him generate a .357/.421/.634 slash line with 13 extra-base hits and 27 RBI across 126 plate appearances.

Stanton isn't in the Yankees' lineup Wednesday versus the Mariners.

Slashing just .171/.271/.390 with four RBI through 48 plate appearances in September, Stanton will take a seat on the bench for the second game in a row Wednesday. Aaron Judge will once again work as New York's DH while Alex Verdugo, Jasson Dominguez and Juan Soto start across the outfield.

Manzardo is out of the lineup for Wednesday's game against the Twins.

Manzardo had served as the Guardians' designated hitter in both of the team's last two matchups with righties, but he'll head to the bench Wednesday even though Minnesota is sending right-hander Bailey Ober to the hill. David Fry will fill in for Manzardo at DH and will bat fifth.