Beeter struck out one and walked two in a scoreless eighth inning during Thursday's 10-4 win over the Cubs.

The Nationals held an 8-4 lead when Beeter took the mound to face the bottom half of Chicago's batting order -- not exactly a high-leverage spot for the 2026 debut of a pitcher generally projected to lead the team in saves this season. Washington doesn't have any established options at the back of its bullpen, however, so as long as Beeter remains effective, he should be in the mix to protect close ninth-inning leads. The 27-year-old right-hander will need to display more control than he did Opening Day to stay in the saves picture, as he tossed just 12 of 24 pitches for strikes against the Cubs. Cole Henry and potentially Cionel Perez, who worked the ninth Thursday, could also get save chances while new manager Blake Butera sorts out his bullpen.

Pivetta (0-1) took the loss Thursday versus Detroit, allowing six runs on seven hits and three walks while striking out four batters over three innings.

On the heels of his career-best 2025 campaign, Pivetta was awarded his first MLB Opening Day start. However, things didn't go well for the right-hander, as he gave up more earned runs Thursday than he did in all but one outing last year. Pivetta struggled from the get-go, giving up four runs in the first frame. His control was largely to blame -- Pivetta served up three free passes in that opening inning. He'll try to turn things around in his second start, which is tentatively slated to come at home against San Francisco next week.

Duran picked up the save Thursday against the Rangers, allowing one hit and no walks in two-thirds of an inning. He struck out one.

A three-run ninth inning for Texas opened the door for a save situation, allowing the hard-throwing right-hander to enter the game and shut the door for his first save of the season. Duran is set up as Philadelphia's primary closer to open the campaign, after he dazzled a year ago with a 2.18 ERA, 0.92 WHIP and 27:1 K:BB across 20.2 regular-season frames after being acquired by the Phillies at the trade deadline.

Chapman picked up the save Thursday against the Reds, retiring all three batters he faced in the ninth inning.

Although Chapman failed to record a strikeout, he managed to keep the ball in the yard via three flyouts to nail down a save in his first appearance of the campaign. After posting a career-best 1.17 ERA and 0.70 WHIP over 67 regular-season appearances in 2025, the hard-throwing left-hander is locked in as Boston's top closer to begin the season.

Crochet (1-0) picked up the win Thursday against the Reds, allowing no runs on three hits and two walks in six innings. He struck out eight.

The All-Star southpaw found himself in midseason form in his season debut, firing six shutout frames and also notably escaping a bases-loaded jam to close his final frame. Crochet was also able to throw 80 pitches Thursday, and his final start during spring training saw him hurl 89 pitches. He should build up to closer to a full workload in his next start, which is slated to come in Houston next week.

Smith (0-1) took the loss Thursday against the Brewers, allowing four runs (three earned) on three hits and two walks while striking out two over 1.2 innings.

Smith cruised through a scoreless first inning before unraveling in the second, with the damage highlighted by a bases-clearing double from William Contreras. After laboring through 54 pitches and only recording five outs, Thursday marked the shortest outing of the right-hander's young career. After an All-Star rookie campaign in 2025 that saw him hold a 3.81 ERA with 145 strikeouts in 146.1 innings, Smith will look to move past this disastrous performance and return to his previous form in his next scheduled start, which tentatively lines up to come in Miami.

Stanek picked up the save Thursday against the Rays, allowing no hits and three walks in a scoreless ninth inning. He struck out one.

The right-hander drew St. Louis' first save opportunity of the year in his team debut, suggesting he's firmly in the mix for ninth-inning work. It's perhaps too early to tell if he'll get the bulk of the save chances in 2026, but Stanek could be worth a speculative pickup in fantasy leagues as this situation shakes out. JoJo Romero and Riley O'Brien worked the seventh and eighth innings respectively Thursday.

Rogers allowed one hit while striking out one over a scoreless inning in Thursday's 2-1 loss against Baltimore.

Rogers was used in the eighth inning in a game the Twins were trailing 2-1. It was a high-leverage situation, but Cole Sands was warming up in case the Twins tied the game or took the lead. Rogers may still figure into the closer mix, but manager Derek Shelton has said he's still figuring out his bullpen and roles will be determined by performance early in the season.

Jax blew the save Thursday against the Cardinals, allowing one run on one hit in two-thirds of an inning.

The Rays had mounted a 7-1 lead in the sixth inning before St. Louis came roaring back in the second half of the frame, and Jax was unable to put out the fire. The right-hander entered the year as one of Tampa Bay's favorites for saves, with Edwin Uceta (shoulder) on the injured list, but Thursday's effort won't do him many favors. That said, Garrett Cleavinger gave up two runs in one-third of an inning, so this closer committee appears to be very much unsettled.

Topa allowed one run on two hits with no walks or strikeouts over one inning in Thursday's 2-1 loss against the Orioles.

Topa was used in the seventh inning in a tied game in his first appearance. While he could be used in late-inning save situations at some point, his first usage of the season wouldn't seem to indicate he's at the top of the mix for save opportunities.