Ryan (0-1) allowed five runs on nine hits and struck out three without walking a batter over four innings to take the loss Wednesday versus the Royals.

Ryan didn't give up a ton of hard contact, but the Royals strung together a three-run tally in the second inning and added an additional run in each of the third and fourth frames. The right-hander exited at 77 pitches (49 strikes) in a disappointing follow-up to his 5.1 scoreless innings versus the Orioles on Opening Day. Ryan is keeping the walks down with a 10:2 K:BB over 9.1 innings so far, but he will need to avoid putting traffic on the bases, which can bite him if an opponent can generate some power against the flyball pitcher. Ryan is tentatively lined up to make his next start at home in a tough matchup versus the Tigers early next week, which could be the first outing of a two-start week for the Twins' ace.

Williams (1-1) allowed two hits and three walks while striking out 10 over seven scoreless innings to earn the win over the Dodgers on Wednesday.

Williams looks to have corrected the mechanical issue that led to him walking six batters in his season debut versus the Mariners. The right-hander was excellent in this contest, though he's unlikely to ever be an elite control pitcher. That didn't get in his way in 2025, and he's now given up a modest three runs over 12 innings while posting a 17:9 K:BB through his first two starts of 2026. Williams is projected to make his next start at home versus the Royals next week.

Kirby (1-1) took the loss Wednesday against the Yankees, allowing four runs on five hits and three walks in six innings. He struck out six.

The right-hander gave up just one run through five frames, but Paul Goldschmidt's three-run homer in sixth inning left a big mark on Kirby's ledger. Kirby has now gone at least six innings in each of his first two starts of the year, but he's now been taken deep twice already. The right-hander will try to keep the ball in the yard the next time he takes the mound, which is set come in Texas versus the division-rival Rangers next week.

Schlittler (2-0) notched the win Wednesday against the Mariners, allowing no runs on two hits and no walks in 6.1 innings. He struck out seven.

After giving up just one hit in his season debut against the Giants, Schlitter was nearly unhittable again Wednesday. The Mariners offered very little resistance against the right-hander, who pounded the zone for 58 strikes out of his 79 pitches while posting a strong 13 swings-and-misses. Schlittler has a shiny 15:0 K:BB through his first 11.2 frames of 2026, and he'll be looking to touch the 80-pitch marker for the first time this year in his next scheduled outing against the Athletics.

Skubal (0-1) took the loss Wednesday against the Diamondbacks, allowing one run on six hits and no walks in seven innings. He struck out three.

The All-Star left-hander certainly wasn't deserving of the loss, but the Tigers were shut out Wednesday. Skubal had the Arizona bats off balance throughout the outing, inducing 10 groundouts while pouring in 60 of his 87 pitches for strikes, but Corbin Carroll managed to take Skubal deep in the first innings for the game's lone run. Skubal has permitted a single run on the campaign to go with a pristine 9:0 K:BB through 13 innings so far, and he'll look to keep dealing his next time out versus the Twins in Minnesota.

Burrows (1-1) earned the win Wednesday over the Red Sox, allowing two runs on five hits and three walks over five innings. He struck out six.

Burrows had to contend with traffic Wednesday, though he managed to hold Boston to a pair of runs en route to his first win with the Astros. It was a nice rebound effort overall from Burrows after he gave up five runs on nine hits in his first start against the Angels. The right-hander is currently slated to face the Rockies at Coors Field his next time out.

Rasmussen allowed two runs (one earned) on two hits and a walk across five innings Wednesday against the Brewers. He struck out eight.

Rasmussen matched his 2025 season high with eight strikeouts Wednesday. The right-hander has been sharp in two starts to open the 2026 campaign, allowing just two earned runs on six hits across 10 innings. Rasmussen will look to keep it going in his next outing, tentatively scheduled to come next week at home against the Cubs.

Kikuchi (0-1) took the loss Wednesday against the Cubs, allowing five runs on six hits and four walks in 5.1 innings. He struck out five.

Although Kikuchi managed to keep the ball in the yard, the four free passes he piled up came back to haunt him a bit. Two of which came in the third inning, when the Cubs strung together five hits and tagged the left-hander for each of his five runs allowed. Kikuchi's next start is scheduled for next week at home against Atlanta, and he'll be aiming to get back on track after yielding seven runs across his first 9.2 innings of 2026.

Rogers (2-0) picked up the win Wednesday. allowing two runs on six hits and a walk over six innings in an 8-3 victory over the Rangers. He struck out three.

Baltimore's offense jumped on Nathan Eovaldi early, and Rogers already had a 4-0 lead before Texas got to the southpaw for a couple runs in the fourth inning. Rogers has delivered back-to-back quality starts to begin the season, posting a 1.38 ERA, 1.08 WHIP and 8:5 K:BB through 13 innings. He'll look to extend his win streak in his next start, which lines up to come on the road early next week against the White Sox.

Eovaldi (0-2) took the loss Wednesday, surrendering six runs on eight hits and three walks over four-plus innings as the Rangers fell 8-3 to the Orioles. He struck out five.

The right-hander dealt with runners in scoring position in each of the first three innings, but after he seemed to settle down with a 1-2-3 fourth, Samuel Basallo led off the fifth with a solo shot. Eovaldi's had a rough start to 2026, getting tagged for 11 runs in 8.2 innings despite a 12:3 K:BB, and he's having trouble keeping the ball in the yard. After serving up just 10 homers in 22 starts as part of his career year in 2025, Eovaldi has already coughed up three homers in two starts to kick off the current campaign. He'll look to regain his focus in his next outing, which is set to come at home early next week against the Mariners.