Cannon (4-9) allowed seven runs on four hits and three walks over 1.2 innings to take the loss against Seattle on Wednesday. He struck out three batters.

Cannon fell behind quickly, giving up a two-run home run to Josh Naylor in the first inning. Things got even worse for the hurler in the second, as the Mariners put five more runs on the board, the final three of which came on a Julio Rodriguez three-run homer. The seven total runs Cannon allowed were his most so far this season, and he's now given up a total of 19 runs (18 earned) across 12 innings over his past three starts. The rough stretch has ballooned his season ERA from 4.18 to 5.34.

May (6-8) took the loss Wednesday against the Royals, allowing three runs on six hits and one walk in 3.2 innings. He struck out four.

Kansas City made May work, as the hurler was unable to make it through four innings despite throwing 91 pitches. Wednesday represented the shortest outing of the season for May, who has worked at least five frames on just two occasions over his last six starts. The 27-year-old right-hander holds a lackluster 4.93 ERA, 1.37 WHIP and 101:44 K:BB across a career-high 107.2 innings, and he'll likely remain a volatile fantasy option in Houston against the first-place Astros his next time out.

Wacha (6-9) recorded the win Wednesday against the Red Sox, allowing two runs on five hits and no walks in six innings. He struck out three.

It was Wacha's fifth start in a row with at least five innings while conceding two runs or fewer. While the veteran right-hander has exceeded five strikeouts on just four occasions out of his 23 starts on the year, he's now up to 11 quality starts in 2025. Wacha has a steady 3.36 ERA, 1.15 WHIP and 98:35 K:BB over 131.1 frames, and his next appearance projects for a soft matchup at home versus the Nationals.

Kirby (7-5) earned the win over the White Sox on Wednesday, allowing two runs on five hits and two walks while striking out nine batters over six innings.

Kirby had his swing-and-miss stuff working, as he racked up a hearty 19 whiffs and nine punchouts. The right-hander didn't give up any extra-base hits among the five knocks he allowed and fired a first-pitch strike to 17 of the 25 batters he faced. Kirby also recorded his third straight quality start and has posted six such outings over his past eight appearances. His 4.04 ERA is still well below his career norm, but Kirby has yielded two or fewer earned runs in nine of his 14 starts on the season.

Flaherty (6-11) took the loss against the Twins on Wednesday, allowing six runs (five earned) on eight hits and one walk with three strikeouts over 4.2 innings.

Flaherty allowed runs in four separate innings and struggled to locate, throwing just 49 of 82 pitches for strikes while generating only four whiffs. The 29-year-old entered the contest with back-to-back quality starts and a 2.40 ERA over three outings since the All-Star break, but Wednesday marked the fifth time he's allowed five or more runs this season. He owns a 4.56 ERA, 1.28 WHIP and 147:48 K:BB across 120.1 innings and will look to rebound in a road matchup with the White Sox early next week.

Springs didn't factor into the decision Wednesday against the Nationals, allowing one run on one hit and no walks in six innings. He struck out five.

Springs brought a bid for a perfect game into the sixth inning, but he was taken deep by Riley Adams to end those hopes. The left-hander hurled at least six innings for the fifth time in his last six starts, and he's become a fairly consistent fantasy play following a sluggish start to the year that saw him post a 6.04 ERA through April 26. Springs owns a 3.30 ERA, 0.98 WHIP and 80:24 K:BB over 103.2 innings since the start of May, and he's next lined up for a favorable home matchup versus a Rays team with a .591 OPS against left-handed pitching since the beginning of July.

Leiter came away with a no-decision in Wednesday's 3-2 loss to the Yankees, giving up two runs (one earned) on three hits and four walks over 3.1 innings. He struck out three.

The young righty threw only 33 of 68 pitches for strikes before getting the hook, as Leiter failed to complete at least five innings for the third time in six starts since the beginning of July. Despite those struggles, he's still managed to post a respectable 3.45 ERA and 35 strikeouts in 28.2 innings over that stretch, albeit with a 1.46 WHIP and 20 walks. Leiter will look to improve his efficiency in his next trip to the mound, which is scheduled to come at home early next week against the Diamondbacks.

Rodon came away with a no-decision in Wednesday's 3-2 win over the Rangers, giving up two runs on six hits and four walks over five-plus innings. He struck out three.

The veteran lefty once again struggled to get the ball over the plate consistently, issuing at least three free passes for the fifth time in his last seven starts. Over that stretch, Rodon has produced a 4.50 ERA, 1.42 WHIP and 40:22 K:BB in 38 innings. He'll try to tighten things up in his next outing, which lines up to come at home early next week against the Twins.

Arrighetti (1-2) took the loss Wednesday against the Marlins, allowing five runs on 11 hits and one walk in 3.2 innings. He struck out five.

Arrighetti showed plenty of rust and a lack of command on his pitch locations in his first major-league start since April 5 in Minnesota, surrendering a career-high 11 hits Wednesday in his first game back from a thumb fracture. The 25-year-old right-hander did produce 16 whiffs during his abbreviated outing, which was perhaps an encouraging takeaway, but he may have been a bit too aggressive in attacking the strike zone overall. Arrighetti has a rough 7.43 ERA, 1.58 WHIP and 13:6 K:BB over his first 12.2 innings this year, so he'll try to right the ship during a scheduled home tilt versus the Red Sox his next time out.

Anderson did not factor into the decision Wednesday against the Rays, allowing four runs on five hits and a walk over four innings. He struck out five.

Anderson was done in by the home-run ball again Wednesday -- all four of Tampa's runs off the left-hander came via the long ball, including two off the bat of Junior Caminero. Anderson's given up eight homers across 14.2 innings in his last three starts. He remains without a win since April 18 and sports a 4.63 ERA with a 1.40 WHIP and 97:47 K:BB through 23 starts (122.1 innings) this season. He's currently lined up for a tough home matchup with the Dodgers in his next outing.