Manager Craig Albernaz said after Tuesday's loss to the Rangers that he expects Eflin (elbow) to be placed on the injured list, Andy Kostka of TheBaltimoreBanner.com reports.

Eflin made an early exit from Tuesday's contest after 3.2 innings of one-run ball due to elbow discomfort. He's scheduled to receive an MRI on his elbow Wednesday, but the Orioles don't seem to be very optimistic about what the results will show. A clearer timeline for the right-hander's return will emerge once the team knows the extent of the damage done.

Rodon (elbow) reported tightness in his right hamstring Tuesday, Bryan Hoch of MLB.com reports.

Rodon has been working his way back from a procedure he underwent in the offseason to remove a bone spur from his left elbow. However, he now appears to be battling a hamstring injury he suffered while running. Manager Aaron Boone said the left-hander still threw Tuesday despite his new injury, and it remains unknown whether his season debut -- tentatively scheduled for late April -- will be delayed.

Eflin was removed from Tuesday's game against the Rangers due to right elbow discomfort, Roch Kubatko of MASNSports.com reports.

Eflin had allowed one earned run on four hits and two walks while striking out seven batters before one of the Orioles' trainers made the call to pull him with two outs in the fourth inning. It's unclear whether the 31-year-old righty is dealing with any structural damage, but the team should provide an update on his status in the near future.

Sloan is opening the season with Double-A Arkansas, Daniel Kramer of MLB.com reports.

Few prospects generated more rave reviews this spring than Sloan, whose already plus fastball jumped a couple ticks and now sits around 97 mph. Sloan, who could be the game's top pitching prospect in a couple months, only made three starts at High-A last year, so this is a big vote of confidence. Per the report, the initial plan was to assign Sloan to High-A Everett, but the calculus changed after he made such a strong impression this spring. The less volatile weather conditions in Arkansas compared to the Pacific Northwest in April also factored into the decision. What makes the assignment even more notable is that the Mariners have a track record of jumping their best pitching prospects from Double-A to the majors, bypassing the Pacific Coast League. Kade Anderson, the Mariners' other premium pitching prospect, is also opening the year at Double-A.

Anderson is opening the season with Double-A Arkansas, Daniel Kramer of MLB.com reports.

Most of the top college arms get assigned to High-A for their first full season, so while this assignment may not be a big surprise, it is notable. Per the report, the initial plan was to assign Anderson to High-A Everett, but the calculus changed after Anderson made such a strong impression this spring. The less volatile weather conditions in Arkansas compared to the Pacific Northwest in April also factored into the decision. What makes the assignment even more notable is that the Mariners have a track record of jumping their best pitching prospects from Double-A to the majors, bypassing the Pacific Coast League. Ryan Sloan, the Mariners other premium pitching prospect, is also opening the year at Double-A.

Varland (0-1) took the loss Monday as the Blue Jays fell 14-5 to the Rockies, allowing an unearned run on two hits over 1.1 innings of relief. He struck out three without walking a batter.

The right-hander pitched well in a tough spot, as Varland was called in when Cody Ponce (knee) was removed from the game in the third inning, but the unearned run he gave up in the fourth wound up being the one that put Colorado in the lead for good. Varland's seen a heavy workload early, appearing in three of the Jays' first four games and posting a 0.00 ERA, 1.80 WHIP and 5:2 K:BB over 3.1 innings with a hold.

Weiss delivered two hitless innings in relief in Monday's win over the Red Sox, striking out three while walking one.

Weiss failed to crack Houston's rotation out of spring training, though he did make the team as a bullpen option. The right-hander looked sharp Monday, as he set down six straight Red Sox after issuing a leadoff walk in the eighth. It was an encouraging performance for Weiss, after he gave up a home run to Zach Neto in his major league debut Friday. While Weiss could work his way into the high-leverage picture, he's more likely to serve as a swingman or long-relief option this year.

DeGrom (neck) has been cleared to start Tuesday's game in Baltimore.

DeGrom had to be scratched from his first scheduled start of the season Saturday in Philadelphia due to neck stiffness, but he's improved enough in the days since then to take the ball Tuesday. With deGrom ready to go, Jacob Latz -- who tossed four scoreless frames in a spot start in deGrom's stead versus the Phillies -- will head back to the bullpen.

Bassitt (0-1) took the loss Monday against the Rangers, allowing four runs on six hits and four walks while striking out three in 4.1 innings pitched.

All of the damage done against Bassitt came in the first two innings of his Orioles tenure. He allowed one run in the first inning on a fielder's choice, but the crushing inning was the second. Three hits, two walks and a sacrifice fly contributed to the Rangers plating three runs in the frame and jumping out to a 4-0 lead that the Orioles would not be able to recover from. The 37-year-old will look to find better success in his next outing, scheduled for Sunday against the Pirates.

Castillo did not factor into the decision Monday against the Yankees, allowing two hits and two walks while striking out seven over six scoreless innings.

Castillo was in complete control, holding the Yankees hitless until the fourth inning and limiting them to just two hits overall. The right-hander generated 17 whiffs and leaned heavily on his primary arsenal, throwing 87 of his 95 pitches as either a fastball or slider. Castillo had hitters fooled all night, but his final strikeout was a milestone moment, as he got Aaron Judge to swing through an inside breaking ball for his 1,500th career strikeout before exiting after the sixth inning. The 33-year-old will look to replicate Monday's success in his next scheduled start against the Angels.